Helicobacter pylori infection in HIV-positive patients with digestive complaints

Abstract

Background. Patients infected with human immunodeficiency virus (HIV), especially at advanced stages of HIV infection and low CD4+ T-lymphocytes levels, were reported to be less frequently co-infected with Helico-bacter pylori than general population, according to literature data.

Effect of H.pylori Infection on CD4+T Cell Count and Hiv Viral Load Among Art and Naïve Art Hiv Patients in Mekelle City, Tigray, Northern Ethiopia

“…ART exposure decreased participants' viral load level with H pylori patients, but not signi cantly, compared to patients without H pylori, with a median(IQR) of 2.17(1.87-3.53) versus 2.45(1.97-4.26) log10 copies/ml, P=0.056), consistent with the studies Ghana [41] with a median(IQR) of 1.59(1.59-2.19) and Romania [9] with a median of undetectable. In the current nding participants' viral load level with H. pylori patients among ART exposed was found tend to be lowered, however, it does not reach signi cant difference compared to without H. pylori control patients with a median(IQR) of 2.17(1.87-3.53) versus 2.45(1.97-4.26) log10 copies/ml, p=0.056) which was parallel with study at Ghana [41] with median(IQR) of 1.59(1.59-2.19) and Romania [9]with median of undetectable. However, a study conducted in Belgium [40] reported a lowered effective signi cant difference of viral load level with a median(IQR) of 50(50-50) versus 50(50-13800) compared to the controls.…”

“…Chronic infections are commonly associated with advanced HIV disease [9]. The study reported H. pylori exists in HIV infected patients [10][11].…”