Helicobacter pylori in immigrants: a “foreign” bacterium?

Zullo, Angelo; Cristofari, Francesca; Bragazzi, Maria Consiglia; Hassan, Cesare

doi:10.1007/s11739-010-0477-3

Cited by 4 publications

(1 citation statement)

References 10 publications

(15 reference statements)

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“…In adults, a study conducted in Toronto, Ontario, found a prevalence of 23.1% (5), whereas rates as high as 95% have been reported in some Aboriginal communities (9). The largest emigrations to Canada in the most recent Statistics Canada census were from China, India, the Philippines and Pakistan (10), all of which have high endemic rates of H pylori infection that would be expected to be represented in these immigrants (11).…”

Section: L'helicobacter Pylori Au Sein Des Populations Des Premières mentioning

confidence: 99%

Helicobacter pyloriin First Nations and Recent Immigrant Populations in Canada

Jones

Chiba

Fallone

et al. 2012

Canadian Journal of Gastroenterology

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The diminishing prevalence of Helicobacter pylori infection among most segments of the Canadian population has led to changes in the etiologies and patterns of associated upper gastrointestinal diseases, including fewer peptic ulcers and their complications. Canadian Aboriginals and recent immigrants are among populations in which the prevalence of H pylori infection remains high and, therefore, the health risks imposed by H pylori remain a significant concern. Population-based strategies for H pylori eradication in groups with a low prevalence of infection are unlikely to be cost effective, but such measures are attractive in groups in which the prevalence rates of infection remain substantial. In addition to a lower prevalence of peptic ulcers and dyspepsia, the public health value of eradication may be particularly important if this leads to a reduction in the prevalence of gastric cancer in high prevalence groups. Therefore The Canadian Helicobacter Study Group held a conference that brought together experts in the field to address these issues, the results of which are reviewed in the present article. Canadians with the highest prevalence of H pylori infection are an appropriate focus for considering the health advantages of eradicating persistent infection. In Canadian communities with a high prevalence of both H pylori and gastric cancer, there remains an opportunity to test the hypothesis that H pylori infection is a treatable risk factor for malignancy.

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Section: L'helicobacter Pylori Au Sein Des Populations Des Premières mentioning

confidence: 99%

Helicobacter pyloriin First Nations and Recent Immigrant Populations in Canada

Jones

Chiba

Fallone

et al. 2012

Canadian Journal of Gastroenterology

View full text Add to dashboard Cite

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Role of gastritis pattern on Helicobacter pylori eradication

Zullo

Severi

Vannella³

et al. 2011

Intern Emerg Med

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Helicobacter pylori eradication rate following standard triple therapy is decreasing. Identification of predictive factors of therapy success would be useful for H. pylori management in clinical practice. This study aimed to evaluate the role of different gastritis patterns on the efficacy of the currently suggested 14-day triple therapy regimen. One-hundred and seventeen, consecutive, non-ulcer dyspeptic patients, with H. pylori infection diagnosed at endoscopy, were enrolled. All patients received a 14-day, triple therapy with lansoprazole 30 mg, clarithromycin 500 mg and amoxicillin 1 g, all given twice daily. Bacterial eradication was assessed with (13)C-urea breath test 4-6 weeks after completion of therapy. H. pylori infection was cured in 70.1% at ITT analysis and 83.7% at PP analysis. The eradication rate tended to be lower in patients with corpus-predominant gastritis as compared to those with antral-predominant gastritis at both ITT (66.1 vs 74.5%) and PP (80.4 vs 87.2%) analyses. The multivariate analysis failed to identify factors associated with therapy success. However, 14-day triple therapy does not achieve acceptable H. pylori cure rate in Italy, and should be not recommended in clinical practice.

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