Helicobacter pylori eradication in the treatment of gastric hyperplastic polyps: beyond National Health Insurance

Koh, Jin Sung; Joo, Moon Kyung

doi:10.3904/kjim.2018.122

Cited by 6 publications

(6 citation statements)

References 9 publications

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“…A total of 88 polyploid wound lesions were detected in these patients. Histopathological examination of polyps showed that HPs accounted for 80.7%, inflammatory polyps 17%, and APs 2.3% [33] . FGP was not detected.…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of gastric polyps in patients with upper gastrointestinal endoscopy

Zheng

Wen

Dai

et al. 2019

Preprint

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BACKGROUNDAccording to the study population, incidence of gastric polyps (GP) varies from 0.33% to 6.7% in various studies. Most GPs consist of proliferative polyps (HP), gastric fundus polyps (FGP) and adenomatous polyps (APs). Despite the high malignant AP potential, sporadic FGP has no malignant potential. On the contrary, HP has a lower risk of potential harm. It is not sufficient to perform biopsies to determine the presence of polyp types and displacements, therefore, some polyps may require extensive biopsy or complete resection. METHODS This retrospective study included GP patients or polyphenic lesions with polyps or malignant histologyfound in polyps or gastroscopy at the Department of Gastroenterology, Shaanxi Hospital of Traditional Chinese Medicine from 2017 to 2019. RESULTSIn a series of 10.000 upper gastrointestinal endoscopy, 384 patients (0.38%) were found to have GPs.Of these patients, 98 (25.5) were male and 286(74.5) were female. The average age of the patients

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Section: Discussionmentioning

confidence: 99%

“…These polyps are not always diagnosed as endoscopic biopsies because they are local [33] . Because our case was not diagnosed by endoscopic biopsy, it was diagnosed after surgical removal [34] .…”

Section: Discussionmentioning

confidence: 99%

Evaluation of gastric polyps in patients with upper gastrointestinal endoscopy

Zheng

Wen

Dai

et al. 2019

Preprint

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“…In the atrophy area, there may be a large amount of infiltration of lymphocytes and plasma cells, often spreading to the entire layer of the mucosa, forming lymphoid follicles. IM is a common pathological change in atrophic gastritis[ 12 - 15 ]. It is not comprehensive to report only mild, moderate, and severe CAG in clinical pathologic diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Histopathological classification and follow-up analysis of chronic atrophic gastritis

Wang¹,

Shen²,

Tian³

et al. 2021

WJCC

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BACKGROUND The pathological diagnosis and follow-up analysis of gastric mucosal biopsy have been paid much attention, and some scholars have proposed the pathological diagnosis of 12 kinds of lesions and accompanying pathological diagnosis, which is of great significance for the treatment of precision gastric diseases, the improvement of the early diagnosis rate of gastric cancer, and the reduction of missed diagnosis rate and misdiagnosis rate. AIM To perform a histopathological classification and follow-up analysis of chronic atrophic gastritis (CAG). METHODS A total of 2248 CAG tissue samples were collected, and data of their clinical characteristics were also gathered. Based on these samples, the expression levels of Mucin 1 (MUC1), MUC2, MUC5AC, and MUC6 in CAG tissue were tested by immunohistochemical assay. Moreover, we followed these patients for up to four years. The difference between different stages of gastroscopic biopsy was observed. RESULTS Through observation, it is believed that CAG should be divided into four types, simple type, hyperplasia type, intestinal metaplasia (IM) type, and intraepithelial neoplasia (IEN) type. Simple CAG accounted for 9.1% (205/2248), which was more common in elderly people over 60 years old. The main change was that the lamina propria glands were reduced in size and number. Hyperplastic CAG accounted for 29.1% (654/2248), mostly occurring between 40 and 60 years old. The main change was that the lamina propria glands were atrophy accompanied by glandular hyperplasia and slight expansion of the glands. IM CAG accounted for 50.4% (1132/2248), most of which increased with age, and were more common in those over 50 years. The atrophy of the lamina propria glands was accompanied by significant IM, and the mucus containing sialic acid or sulfate was distinguished according to the nature of the mucus. The IEN type CAG accounted for 11.4% (257/2248), which developed from the previous types, with severe gland atrophy and reduced mucus secretion, and is an important precancerous lesion. CONCLUSION The histological typing of CAG is convenient to understand the property of lesion, determine the follow-up time, and guide the clinical treatment.

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“…Animal experiments have revealed that gastrin can promote the growth of parietal cells by increasing their height and size [32] . When the parietal cells in the neck of gland are enlarged, they may block the opening of the gland and increase the pressure inside the gland, leading to the development of cystic changes and eventually the forming of polyps [33] .…”

Section: Discussionmentioning

confidence: 99%

“…In addition, IFP was detected in one patient in our study. These polyps are not always diagnosed as endoscopic biopsies because they are local [33] . Because our case was not diagnosed by endoscopic biopsy, it was diagnosed after surgical removal [34] .…”

Section: Discussionmentioning

confidence: 99%

Evaluation of gastric polyps in patients with upper gastrointestinal endoscopy

zheng¹,

wen²,

Dai³

et al. 2020

Preprint

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Background:According to the study population, incidence of gastric polyps (GPs) varies from 0.33% to 6.7% in various studies. Most GPs consist of hyperplastic polyps (HPs), fundic gland polyps (FGPs), and adenomatous polyps (APs). Despite the high malignant APs potential, sporadic FGPs has no malignant potential. On the contrary, HPs has a lower risk of potential harm. It is not sufficient to perform biopsies to determine the presence of polyp types and displacements, therefore, some polyps may require extensive biopsy or complete resection. MethodsThis retrospective study included GPs patients or polyphenic lesions with polyps or malignant histology found in polyps or gastroscopy at the Department of Gastroenterology, Shaanxi Hospital of Traditional Chinese Medicine from 2017 to 2019.ResultsIn a series of 10.000 upper gastrointestinal endoscopy, 384 patients (3.84%) were found to have GPs. Of these patients, 98 (25.5) were male and 286(74.5) were female. The average age of the patients was 62.8±10.4 (36-75) years. HPs, APs and FGPs frequencies were 88.5%, 5.2% and 2.1%, respectively. The polyp size of 274 (71.3%) patients was ≤ 1 cm. Polyp was identified in 262 (68.2%) patients. The most common polyps are the antrum and the corpus. Endoscopic mucosal resection was performed on 128 patients. Bleeding events have been observed and endoscopic treatment is required after ESP.Conclusion: In current study, GPs frequency was low (3.84%), and HP frequency may be high due to high frequency of Helicobacter pylori (HPy) infection in China. Due to the high frequency of HPy infection and the short-term use of proton pump use, FGP frequency may be low.

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Helicobacter pylori eradication in the treatment of gastric hyperplastic polyps: beyond National Health Insurance

Cited by 6 publications

References 9 publications

Evaluation of gastric polyps in patients with upper gastrointestinal endoscopy

Evaluation of gastric polyps in patients with upper gastrointestinal endoscopy

Histopathological classification and follow-up analysis of chronic atrophic gastritis

Evaluation of gastric polyps in patients with upper gastrointestinal endoscopy

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