1996
DOI: 10.1097/00005176-199602000-00004
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Helicobacter pylori and Recurrent Abdominal Pain in Children

Abstract: Recurrent abdominal pain is one of the most common presentations to pediatricians; yet an organic etiology can be found in only 10% of cases. Because infection with Helicobacter pylori in adults and children results in gastritis, a causative role for the organism has been postulated. To investigate this theory, we conducted a prospective case-control study in children with recurrent abdominal pain using serum H. pylori IgG antibodies measured by an enzyme immunoabsorbent assay. Age, sex, ethnicity, and socioec… Show more

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Cited by 53 publications
(37 citation statements)
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“…Also, the control group included children with concurrent gastrointestinal disease. Other community based case-control studies have found no association between H pylori infection and recurrent abdominal pain 4 5…”
Section: Commentmentioning
confidence: 92%
“…Also, the control group included children with concurrent gastrointestinal disease. Other community based case-control studies have found no association between H pylori infection and recurrent abdominal pain 4 5…”
Section: Commentmentioning
confidence: 92%
“…The lack of such a tool is a major limitation in the interpretations that can be drawn from the large number of singlecenter studies performed in H. pylori-infected children with abdominal pain. Six studies have been performed in North America, Europe, and Australia, with 2715 children evaluated by esophagogastroduodenoscopy and biopsy, serology, or urea breath test [12••,72••, [73][74][75][76][77]. These studies were limited by differing entry assessment criteria and the lack of validated symptom assessment instruments.…”
Section: Abdominal Painmentioning
confidence: 99%
“…Cependant certains auteurs ont suggéré que la présence de douleurs abdominales réveillant l'enfant, de douleurs calmées par l'ingestion d'aliments, de douleurs associées aux repas, de douleurs post-prandiales, ou de mauvaise haleine matinale (halitose) permet de distinguer les enfants ayant un ulcère de ceux présentant une infection à H. pylori sans ulcère [24]. Plusieurs auteurs n'ont trouvé aucune relation entre infection à H. pylori et présence de douleurs abdominales récurrentes ou vomissements en comparaison à une population contrôle asymptomatique [25][26][27][28] [31]). Enfin, une méta-analyse incluant 45 études pédiatriques montre chez des enfants ayant eu une endoscopie digestive pour douleurs abdominales récurrentes que la prévalence de l'infection à H. pylori chez les enfants est en moyenne de 22 % (variant de 0 à 81 %) et qu'elle n'est pas corrélée avec la présence de douleurs abdominales récurrentes (seuls 6 % des enfants avaient une infection à H. pylori) [17].…”
Section: Arguments Contre L'association Entre H Pylori Et Douleurs Aunclassified