Helicobacter bilis Contributes to the Occurrence of Inflammatory Bowel Disease by Inducing Host Immune Disorders

Peng, Wei; Zhao, Xinhua; Li, Xiaoan

doi:10.1155/2022/1837850

Cited by 3 publications

(1 citation statement)

References 83 publications

(104 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Clinical manifestations of IBD include abdominal pain, diarrhea, mucopurulent stools, and varying degrees of systemic and extraintestinal symptoms, such as weakness, weight loss, fever, and vomiting[ 18 , 19 ]. Although UC pathogenesis is unknown, disturbances in immune function and systemic immune homeostasis within the intestinal mucosa are believed to be key contributing factors to IBD development[ 20 ].…”

Section: Introductionmentioning

confidence: 99%

Curcumin alleviated dextran sulfate sodium-induced colitis by recovering memory Th/Tfh subset balance

Zheng,

Guo,

Huang

et al. 2023

World J Gastroenterol

View full text Add to dashboard Cite

The liver is one of the organs most commonly involved in metastatic disease, especially due to its unique vascularization. It’s well known that liver metastases represent the most common hepatic malignant tumors. From a practical point of view, it’s of utmost importance to evaluate the presence of liver metastases when staging oncologic patients, to select the best treatment possible, and finally to predict the overall prognosis. In the past few years, imaging techniques have gained a central role in identifying liver metastases, thanks to ultrasonography, contrast-enhanced computed tomography (CT), and magnetic resonance imaging (MRI). All these techniques, especially CT and MRI, can be considered the non-invasive reference standard techniques for the assessment of liver involvement by metastases. On the other hand, the liver can be affected by different focal lesions, sometimes benign, and sometimes malignant. On these bases, radiologists should face the differential diagnosis between benign and secondary lesions to correctly allocate patients to the best management. Considering the above-mentioned principles, it’s extremely important to underline and refresh the broad spectrum of liver metastases features that can occur in everyday clinical practice. This review aims to summarize the most common imaging features of liver metastases, with a special focus on typical and atypical appearance, by using MRI.

show abstract

Section: Introductionmentioning

confidence: 99%

Curcumin alleviated dextran sulfate sodium-induced colitis by recovering memory Th/Tfh subset balance

Zheng,

Guo,

Huang

et al. 2023

World J Gastroenterol

View full text Add to dashboard Cite

show abstract

Phylogenetic analysis of pathogenic genes in Helicobacter species

Xu,

Liu,

et al. 2024

WCJD

View full text Add to dashboard Cite

Bowel inflammatory presentations on computed tomography in adult patients with severe aplastic anemia during flared inflammatory episodes

Zhao¹,

Xue²,

Song³

et al. 2023

World J Clin Cases

View full text Add to dashboard Cite

BACKGROUND Patients with severe aplastic anemia (SAA) frequently present with inflammatory episodes, and during flared inflammatory episodes, hematopoietic function is further exacerbated. The gastrointestinal tract is the most common site for infectious and inflammatory diseases, and its structural and functional features confer on it the most potent capacity to affect hematopoietic and immune functions. Computed tomography (CT) is a readily accessible approach to provide highly useful information in detecting morphological changes and guiding further work-ups. AIM To explore CT imaging presentations of gut inflammatory damage in adult SAA patients during inflammatory episodes. METHODS We retrospectively evaluated the abdominal CT imaging presentations of 17 hospitalized adult patients with SAA in search of the inflammatory niche when they presented with systemic inflammatory stress and exacerbated hematopoietic function. In this descriptive manuscript, the characteristic images that suggested the presence of gastrointestinal inflammatory damage and related imaging presentations of individual patients were enumerated, analyzed and described. RESULTS All eligible patients with SAA had CT imaging abnormalities that suggested the presence of an impaired intestinal barrier and increased epithelial permeability. The inflammatory damages were concurrently present in the small intestine, the ileocecal region and the large intestines. Some readily identified imaging signs, such as bowel wall thickening with mural stratification (“water holo sign”, “fat holo sign”, intramural gas and subserosal pneumatosis) and mesenteric fat proliferation (fat stranding and “creeping fat sign”), fibrotic bowel wall thickening, “balloon sign”, rugged colonic configuration, heterogeneity in the bowel wall texture, and adhered and clustered small bowel loop (including various patterns of “abdominal cocoon”), occurred at a high incidence, which suggested that the damaged gastrointestinal tract is a common inflammatory niche responsible for the systemic inflammatory stresses and the exacerbated hematopoietic failure in patients with SAA. Particularly, the “fat holo sign” was present in 7 patients, a rugged colonic configuration was present in 10 patients, the adhesive bowel loop was present in 15 patients, and extraintestinal manifestations suggestive of tuberculosis infections were present in 5 patients. According to the imaging features, a suggestive diagnosis of Crohn’s disease was made in 5 patients, ulcerative colitis in 1 patient, chronic periappendiceal abscess in 1 patient, and tuberculosis infection in 5 patients. Other patients were diagnosed with chronic enteroclolitis with acutely aggravated inflammatory damage. CONCLUSION Patients with SAA had CT imaging patterns that suggested the presence of active chronic inflammatory conditions and aggravated inflammatory damage during flared inflammatory episo...

show abstract

Helicobacter bilis Contributes to the Occurrence of Inflammatory Bowel Disease by Inducing Host Immune Disorders

Cited by 3 publications

References 83 publications

Curcumin alleviated dextran sulfate sodium-induced colitis by recovering memory Th/Tfh subset balance

Curcumin alleviated dextran sulfate sodium-induced colitis by recovering memory Th/Tfh subset balance

Phylogenetic analysis of pathogenic genes in Helicobacter species

Bowel inflammatory presentations on computed tomography in adult patients with severe aplastic anemia during flared inflammatory episodes

Contact Info

Product

Resources

About