Height Restoration and Preservation in Osteoporotic Vertebral Compression Fractures

Oberkircher, Ludwig; Struewer, Johannes; Bliemel, Christopher; Buecking, Benjamin; Eschbach, Daphne-Asimenia; Ruchholtz, Steffen; Krueger, Antonio

doi:10.1097/bsd.0b013e3182aab205

Cited by 8 publications

(2 citation statements)

References 21 publications

(28 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…After duplication removal and review of title and abstract, 18 full-texts were achieved. Later, 8 studies were extracted because the similar investigated population, [12–19] 3 were extracted because they studied the vertebral samples, not clinical studies, [20–22] and 1 was extracted because the fracture located in sacrum. [23] At last, 6 studies with 833 subjects were included in quantitative synthesis.…”

Section: Resultsmentioning

confidence: 99%

Comparison of radiofrequency kyphoplasty (RFK) and balloon kyphoplasty (BKP) in the treatment of vertebral compression fractures

Feng

Shen²,

Feng³

et al. 2017

Medicine

View full text Add to dashboard Cite

Background:Balloon kyphoplasty (BKP) is a widely adopted minimally invasive treatment for vertebral compression fractures (VCFs), but leakage of cement is a main complication of BKP. A novel vertebral augmentation technique radiofrequency kyphoplasty (RFK) with high viscosity cement was developed in 2009. Here, we aim to evaluate whether RFK can relieve symptoms efficiently and reduce cement leakage.Methods:A literature search was performed using Pubmed, Embase, and Cochrane CENTRAL until September 30, 2016. Both randomized controlled trial (RCT) and non-RCT studies comparing RFK and BKP were included. The main outcomes included pain relief (VAS), functionality improvement (ODI), operation time, reduction of deformity (vertebral height and kyphosis angle), and incidence of cement leakage. The origin of heterogeneity was further explored by subgroup stratification.Results:A total of 6 studies involving 833 patients with VCFs were included. The reduction of VAS score in the RFK group was 3.96 points more than that in the BKP group (P = .0007) postoperatively, and the improvement persisted until 12 months after the surgery (P < .00001). The operation time was shorter in RFK group than that in BKP group (P = .01). The increase of anterior vertebral height shortly after the operation was 0.53 mm greater in RFK group (P = .01). The decrease of kyphotic angle after RFK was 0.63° and 0.92° greater than that after BKP, both immediately and 6 months after operation (P = .002 and P < .00001, respectively). There was no significant difference between the incidence of cement leakage after RFK and BKP (P = .06). Further subgroup analysis stratified by study design indicated that the incidence of leakage decreased 15% in RFK than BPK (P < .00001) in non-RCT subgroup, but RFK and BKP treatments were equivalent in the RCT studies (P = .86).Conclusion:RFK appears to be more effective and safer than BKP in the present meta-analysis. The incidence of cement leakage diverges in RCT and non-RCT studies, so large-sample multicentered RCT studies are required to validate this new surgery system.

show abstract

Section: Resultsmentioning

confidence: 99%

Comparison of radiofrequency kyphoplasty (RFK) and balloon kyphoplasty (BKP) in the treatment of vertebral compression fractures

Feng

Shen²,

Feng³

et al. 2017

Medicine

View full text Add to dashboard Cite

show abstract

“…Compared to traditional balloon kyphoplasty, RF-TVA offers a significantly shortened operation time with comparable clinical results and equal, or even reduced, cement leakage rates [ 5 – 7 ]. Recent studies have demonstrated that RF-TVA represents a promising alternative approach in the treatment of compression fractures [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

Radiofrequency-Targeted Vertebral Augmentation: Case Report of a Patient with 7 Osteoporotic Vertebral Fractures in a Variant of Osteogenesis Imperfecta

Westermann

Eysel

Simons

et al. 2017

Case Reports in Orthopedics

View full text Add to dashboard Cite

Introduction Radiofrequency-targeted vertebral augmentation (RF-TVA) is a recognized treatment for painful compression fractures. RF-TVA in a patient with multiple compression fractures due to type I osteogenesis imperfecta (OI) has not been previously reported. Case Presentation A 54-year-old patient with type I OI is presented with a segmental thoracic hyperkyphosis and 7 recent vertebral compression fractures. Because of persistent severe thoracolumbar back pain despite conservative therapy, RF-TVA was indicated. Nocturnal back pain was almost completely relieved at all postoperative time points evaluated. However, overall pain relief dropped only slightly from 7 to 5 on the numerical rating scale (NRS) at the 6-week follow-up, and there was only a small decrease in the Oswestry Disability Index (ODI) from 72% to 63%. An MRI at the 3-month follow-up revealed hyperintensity at levels T11 and T12, indicating slight recollapsing. At the 6-month follow-up, the ODI improved to 55%, although overall pain had worsened to 6 on the NRS. Pain at rest remained at a very low level. Conclusion Despite the remaining lumbago, RF-TVA may be a good option for patients with OI who have multiple fractures. However, fractures at multiple levels and segmental thoracic hyperkyphosis may increase the risk for recollapsing and ongoing pain.

show abstract

Percutaneous kyphoplasty: Risk Factors for Recollapse of Cemented Vertebrae

et al. 2019

View full text Add to dashboard Cite

Height Restoration and Preservation in Osteoporotic Vertebral Compression Fractures

Abstract: On the basis of our results, the unipedicular RFK in osteoporotic compression fractures might represent a promising alternative for the clinical setting.

Cited by 8 publications

References 21 publications

Comparison of radiofrequency kyphoplasty (RFK) and balloon kyphoplasty (BKP) in the treatment of vertebral compression fractures

Comparison of radiofrequency kyphoplasty (RFK) and balloon kyphoplasty (BKP) in the treatment of vertebral compression fractures

Radiofrequency-Targeted Vertebral Augmentation: Case Report of a Patient with 7 Osteoporotic Vertebral Fractures in a Variant of Osteogenesis Imperfecta

Percutaneous kyphoplasty: Risk Factors for Recollapse of Cemented Vertebrae

Contact Info

Product

Resources

About