Heavy silicone oil tamponade: a multicentre experience

Abstract

ObjectiveTo report multicentred use of the heavy silicone oil Densiron 68 for anatomical reattachment following rhegmatogenous retinal detachment (RRD) repair and its associated complications.Methods and analysisPatients from seven vitreoretinal units within the UK that underwent RRD repair with Densiron 68 between January 2015 and December 2019 were identified. Primary outcome measures were primary and final reattachment rate, retained Densiron and failure rate. Secondary outcome measures were duration of tamponade, final visual acuity (VA) and complications of heavy silicone oil.Results134 eyes of 134 patients were involved in the study. Primary surgical success was achieved in 48.5%, while a final reattachment rate of 73.4% was observed. The mean duration of Densiron 68 tamponade was 139.5 days. Mean final VA was 1.01 (range 0–2.9). 8 eyes (6.0%) required long-term topical steroids for anterior uveitis, whereas none of the eyes required long-term pressure-lowering treatment. Emulsification rate was 10.7% (6 eyes).ConclusionThis is the largest real-world study on Densiron 68 in the UK. Densiron 68 facilitates tamponade of inferior retinal pathology and may be considered as an option for tamponade of inferior retinal pathologies.

Refinements in the use of silicone oil as an intraocular tamponade

“…Developments in IOT technology over the last decade include the development of new tamponade materials, particularly silicone oil-based mixtures which are denser than water (e.g. Densiron 68, [ 4 ]) and hydrogel-based intravitreal tamponades [ 5 , 6 ] with the objective of effectively tamponading inferior retinal breaks (on the lower part of the eyeball) as an alternative to the combination of PDMS IOTs and a scleral buckle. More recently, foldable capsular vitreous bodies (FCVBs) [ 7 , 8 ] have been described to function as an intraocular balloon, inserted after pars planar vitrectomy then filled with liquid, providing a sterile and immobile tamponade.…”

Investigation of Differences in the Techniques of Experimental Vitreo-retinal Operations on Laboratory Animals

“…Однако силиконовая тампонада сопряжена с серьезными осложнениями: повышением внутриглазного давления (ВГД), помутнением хрусталика, миграцией и эмульгированием силиконового масла и др. [3][4][5][6][7][8].…”