Heavy Metals: Source, Toxicity Mechanisms, Health Effects, Nanotoxicology and Their Bioremediation

Siddiqa, Ayesha; Faisal, Muhammad

doi:10.1007/978-3-030-41552-5_6

Cited by 4 publications

(3 citation statements)

References 213 publications

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“…In parallel with the recent increasing world population growth, industrial developments and heavy traffic in cities, heavy metal release into the biosphere caused pollution, and this problem is dramatically increasing day by day [5,6]. The main factors causing the spread of heavy metals to the environment could be by natural and/or anthropogenic sources such as volcanic activities, industrial activities, motor vehicle exhausts, paints, mineral deposits and mining sites, fertilizers and chemicals used in agriculture [2,7,8].…”

Section: Introductionmentioning

confidence: 99%

The effects of cadmium on growth, some anatomical and physiological parameters of wheat (Triticum aestivum L.)

Özyiğit

Baktibekova

Hocaoğlu-Özyiğit

et al. 2021

International Journal of Life Sciences and Biotechnology

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Nowadays, increased population and traffic density, together with the development of industry, caused increasing levels of heavy metals releasing to the environment, and environmental pollution has reached its highest level worldwide. Chemical products, fertilizers, industrial dyes, construction materials, silver dental fillings and vaccines are some of the well-known sources of heavy metals exposed the environment. Toxic heavy metals can normally be present in body parts of living things at very low levels, but at higher concentrations they can show toxic effects depending on species and duration. Among heavy metals, cadmium is one of the most harmful ones to the environment, humans, animals and plants, and can be toxic even at low concentrations. Thus in this study, Cd was applied to the wheat (Triticum aestivum L.) plants grown in Kyrgyzstan in different concentrations (0, 50, 100, 200 and 400 μM for experimental groups) and in addition to accumulations in different plant parts, some growth, development, physiological and anatomic parameters were measured. As a result, it was observed that wheat plants were affected by all Cd concentrations, although they were able to manage lower stress in terms of some parameters. It was also seen that plants were negatively affected by higher levels of Cd stress, although remained alive throughout the experimental period.

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Section: Introductionmentioning

confidence: 99%

The effects of cadmium on growth, some anatomical and physiological parameters of wheat (Triticum aestivum L.)

Özyiğit

Baktibekova

Hocaoğlu-Özyiğit

et al. 2021

International Journal of Life Sciences and Biotechnology

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“…Pollution is considered a serious challenge facing the whole world, particularly in developing countries (Verma, 2020). Due to intensive anthropogenic activities, several deleterious effects on the environment, including aquatic systems, and its resources have occurred (Siddiqa and Faisal, 2020). The freshwater ecosystem includes aquatic habitats that are highly prone to pollution due to the intensive interactions between these habitats and humans (Verma, 2020).…”

Section: Introductionmentioning

confidence: 99%

New Pollution Challenges in Groundwater and Wastewater Due to COVID-19

El-Ramady

Eid

Brevik

2020

Journal of Sustainable Agricultural Sciences

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“…Global environmental pollution and contamination with heavy metals have been on the increase since the 18 th century industrial revolution. This has continued to be a major health problem across the globe (Siddiqa and Faisal, 2020). More so, with recent enormous advancement in technological development and industrialization, heavy metals are now ubiquitously present in the environment with consequent negative impact on all biological systems both plants and animals (Hussain et al, 2020;Wallace and Djordjevic, 2020;Shen et al, 2020;Hareram et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

Ethanol leaf extract of Psychotria microphylla rich in quercetin restores heavy metal induced redox imbalance in rats

Orji

Awoke

Harbor

et al. 2020

Heliyon

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Psychotria microphylla is a plant found in Africa and many parts of the world where the leaves are locally used in folk medicine for the treatment of toxicity related liver diseases. We investigated the antioxidant potentials of ethanol leaf extract of Psychotria microphylla (ELE-PM) in restoring hepatic redox dysregulations in rats exposed to heavy metals. HPLC was used in quantifying the bioactive compounds in ELE-PM. DPPH (1,1-diphenyl-2 picrylhydrazyl), FRAP (Ferric reducing antioxidant power) and NO (Nitric Oxide) assays were used for in vitro studies. The in vivo studies involved 30 rats randomly divided into 5 groups ( n = 6). Group 1 received normal saline (2 mg/kg), group 2, 3, 4 and 5 received a combined solution of Pb(NO 3 ) 2 (11.25 mg/kg) and HgCl 2 (0.4 mg/kg) respectively. After 7 days of heavy metal exposure, groups 3, 4 and 5 received a daily bolus administration of 200, 400 and 600 mg/kg body weight of EE-PM respectively through oral intubation for 28 days. HPLC quantification revealed a high amount of quercetin (27.43 ± 0.04 mg/100g), lower amounts of gallic acid (7.60 ± 0.06 mg/100g) and rutin (0.38 ± 0.009 mg/100g). Additionally, ELE-PM demonstrated strong inhibitory potentials against free radical scavenging activity generated in vitro . More interestingly, administration of ELE-PM significantly ameliorated hepatic redox dysregulations elicited by the exposure of the rats to heavy metals in a dose dependent pattern. ELE-PM is highly rich in flavonoid compound quercetin and perhaps this may be responsible for the strong antioxidant potentials exhibited in this investigation.

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Heavy Metals: Source, Toxicity Mechanisms, Health Effects, Nanotoxicology and Their Bioremediation

Cited by 4 publications

References 213 publications

The effects of cadmium on growth, some anatomical and physiological parameters of wheat (Triticum aestivum L.)

The effects of cadmium on growth, some anatomical and physiological parameters of wheat (Triticum aestivum L.)

New Pollution Challenges in Groundwater and Wastewater Due to COVID-19

Ethanol leaf extract of Psychotria microphylla rich in quercetin restores heavy metal induced redox imbalance in rats

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