Heavy Metals Interactions with Neuroglia and Gut Microbiota: Implications for Huntington’s Disease
Yousef Tizabi,
Samia Bennani,
Nacer El Kouhen
et al.
Abstract:Huntington’s disease (HD) is a rare but progressive and devastating neurodegenerative disease characterized by involuntary movements, cognitive decline, executive dysfunction, and neuropsychiatric conditions such as anxiety and depression. It follows an autosomal dominant inheritance pattern. Thus, a child who has a parent with the mutated huntingtin (mHTT) gene has a 50% chance of developing the disease. Since HTT protein is involved in many critical cellular processes including neurogenesis, brain developmen… Show more
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