Heavy and Light/Moderate Smoking Among Building Trades Construction Workers

Chin, Dal Lae; Hong, OiSaeng; Gillen, Marion; Bates, Michael; Okechukwu, Cassandra A.

doi:10.1111/j.1525-1446.2012.01041.x

Cited by 18 publications

(17 citation statements)

References 63 publications

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“…M0 macrophages were reported to be inversely associated with patients' outcomes in various, such as adrenal cortical carcinoma and lung cancer [46,47]. Nowadays, majority studies evaluated the degree of smoking based on the frequency of tobacco use to define heavy smokers and light smokers without uniform quantifying standards [48][49][50]. Moreover, these cut-offs cannot accurately identify the true degree of smoking because they do not comprehensively consider the DNA damage and microenvironment alteration.…”

Section: Discussionmentioning

confidence: 99%

The benefits of smoking cessation on survival in cancer patients by integrative analysis of multi‐omics data

2020

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Few studies have examined the association between smoking status (including former smokers) at diagnosis and overall survival among cancer patients. We aimed to assess the benefits of quitting smoking on cancer prognosis in cohorts of cancer patient smokers obtained from the Cancer Genome Atlas (TCGA) database. Hazard ratios (HR) were calculated to evaluate smoking behavior at cancer diagnosis (reformed smokers vs. current smokers) in association with overall survival using multivariate‐adjusted Cox regressions analysis. According to our analyses, quitting smoking was the independent protective factor for overall survival in lung squamous cell carcinoma (LUSC) (HR = 0.67, 95% CI = 0.48–0.94). Comprehensive analysis of multicomponent data across reformed and current smokers identified a total of 85 differential expressed genes (DEGs) affected by different modes of genetic and epigenetic regulation, potentially representing cancer drivers in smokers. Moreover, we provided a smoking‐associated gene expression signature, which could evaluate the true effect on prognosis with high power (HR = 1.70, 95% CI = 1.19–2.43, AUC = 0.65, 0.67, and 0.70 for 2‐, 3‐, and 5‐year survival, respectively). This signature was also applicable in other smoking‐related cancers, including bladder urothelial carcinoma (HR = 1.70, 95% CI = 1.01–2.88), cervical carcinoma (HR = 5.69, 95% CI = 1.37–23.69), head and neck squamous cell carcinoma (HR = 1.97, 95% CI = 1.41–2.76), lung adenocarcinoma (HR = 1.73, 95% CI = 1.16–2.57), and pancreatic adenocarcinoma (HR = 4.28, 95% CI = 1.47–12.47). In conclusion, this study demonstrates that quitting smoking at diagnosis decreases risk of death in cancer patients. We also provide a smoking‐associated gene expression signature to evaluate the effect of smoking on survival. Lastly, we suggest that smoking cessation could comprise a part of cancer treatment to improve survival rates of cancer patients.

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Section: Discussionmentioning

confidence: 99%

The benefits of smoking cessation on survival in cancer patients by integrative analysis of multi‐omics data

2020

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“…[172829] These findings supports previously conducted studies involving multiple interventions in the workplace seetings. [3031]…”

Section: Discussionmentioning

confidence: 99%

Outcome of tobacco cessation in workplace and clinic settings: A comparative study

Ransing

Patil

Desai

et al. 2016

J Int Soc Prevent Communit Dent

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Aims and Objectives:Several biological, social, and cultural factors contribute to the poor outcome of tobacco cessation interventions. Inability to engage large number of participants is one of the major identifiable factors. The objective of this study was to compare the outcome of tobacco cessation interventions in the clinical and workplace settings.Materials and Methods:In the present study, we recruited 100 participants in tobacco cessation clinic (TCC) group and workplace group (50 participants in each). Both the groups were regularly intervened and were followed up regularly at 2 weeks, 4 weeks, 3 months, and 6 months. Active interventions in the form of awareness lectures, focused group discussions, and if needed, pharmacotherapy (nicotine/non-nicotine replacement therapy) was carried out for all participants. The outcome was assessed as no change, harm reduction (>50% reduction), complete cessation, and drop out. Statistical analysis of the data was done using the Statistical Package for the Social Sciences version 21.0.Results:At the end of 1 month, there was higher tobacco cessation rate in the workplace group versus TCC group (n = 22, 44% vs n = 9, 18%; P < 0.0001). The tobacco cessation rate was maintained even after 6 months of intervention (n = 30, 60% vs n = 12, 24%; P = 0.002) and dropout rate was also lower among the workplace group than the TCC group (n = 14, 28% vs n = 27, 54%; P < 0.0001).Conclusions:Our study findings suggest that the workplace setting has superior outcome in tobacco cessation and harm reduction than clinical setting. In addition, it is associated with low dropout rate and the cessation effect is maintained over a period of 6 months.

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“…Yet whilst Papadopoulos et al's (2010) work focused on the changing work environment within all industries, more focused research also lends support to the argument that construction work has considerable negative impacts on its workers' health, beyond the more tangible hazards it demands they regularly face on sites. For example, research in the US (Chin et al 2012) found that construction workers are almost twice as likely as the general working population to smoke, and they smoke more. Although this was also associated with sociodemographic characteristics such as age, male gender, lower levels of education and income, it was found to link to social pressures and stressful work, and higher exposure to occupational hazards.…”

Section: Public Health: the Symptomsmentioning

confidence: 99%

Shaping the discourse of worker health in the UK construction industry

Sherratt

2017

Construction Management and Economics

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The UK construction industry is in poor health, statistics show rates of occupational illness significantly higher than for workers in any other industry. Recently, the scope of occupational health management on large sites has increased as public health has become included within the organisational remit. Concerns have been raised around the consequences of this development, its close relationships to Corporate Social Responsibility, and how this is now shaping the wider discourse. To explore this phenomenon, a critical discourse analysis of UK 'construction worker health' has been carried out, using the publicfacing data of ten large UK contractors. Findings show that 'public' has now overtaken 'occupational', the latter restricted to legal compliance presented as corporate citizenship, the former championed as evidence of benevolent organisational values. Yet public health concerns are limited to those of lifestyle and individual responsibility, whilst more complex issues around the social determinants of health as associated with work are missing from the discourse, separating organisations from the impacts of their work on their workers. A contemporary mapping of 'construction worker health' is developed for consideration by industry and academics to support future health initiatives and research.

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Heavy and Light/Moderate Smoking Among Building Trades Construction Workers

Abstract: Addressing the influence of these factors on heavy smoking could lead to the development of targeted, multiple components in comprehensive cessation strategies for blue-collar smokers.

Cited by 18 publications

References 63 publications

The benefits of smoking cessation on survival in cancer patients by integrative analysis of multi‐omics data

The benefits of smoking cessation on survival in cancer patients by integrative analysis of multi‐omics data

Outcome of tobacco cessation in workplace and clinic settings: A comparative study

Shaping the discourse of worker health in the UK construction industry

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