Heat-Stress Influences on Antibody Production in Chicken Lines Selected for High and Low Immune Responsiveness

Donker, R. A.; Neeuwland, M. G. B.; Zijpp, A.J. van der

doi:10.3382/ps.0690599

Cited by 48 publications

(34 citation statements)

References 21 publications

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“…Both primary and secondary antibody responses were significantly decreased when birds were reared under HS conditions. This response was similar to previous observations (Thaxton and Siegel, 1970;Donker et al, 1990;Bartlett and Smith, 2003). However, this is not always the case.…”

Section: Discussionsupporting

confidence: 92%

Dietary vitamin A can improve immune function in heat-stressed broilers

Niu

Wei

Liu

et al. 2009

Animal

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This experiment was undertaken to evaluate the effect of dietary vitamin A on the performance and immune competence of broilers under heat stress (HS). A total of 180 birds, at 22 days of age, were randomly assigned to be reared either at 248C (thermoneutral, TN, 248C, constant) or 248C to 388C (heat stress, HS, cycling) until the age of 42 days. Birds were then supplemented with vitamin A at 750, 1500, 15 000 IU/kg. Each of the 2 3 3 factorially arranged treatments were replicated in six cages, each containing five birds. Humoral immunity was assessed by intravenous injection of 7% sheep red blood cells (SRBC) followed by evaluation of serum for antibody titers in primary and secondary responses. Cell-mediated immunity was assessed by using a Sephadax stimulation method to recruit abdominal exudate cells (AEC) to evaluate macrophage phagocytic ability. Body weight (BW) and feed conversion were significantly affected by dietary vitamin A ( P , 0.05). HS significantly reduced BW, feed intake and feed conversion ( P , 0.05). Numbers of AEC, percentage of macrophages in AEC, phagocytic macrophages, internalized opsonized and unopsonized SRBC were increased by dietary vitamin A ( P , 0.05). Both primary and secondary antibody responses were characterized by increasing titers of antibody to SRBC by dietary vitamin A when birds were exposed to HS ( P , 0.05). Lymphoid organ weights, antibody responses, incidence of macrophages in AEC and phagocytic ability of macrophages were all significantly reduced under HS. These results indicated that HS severely reduced performance and immunocompetence of broilers, whereas the immune response of broilers improved by dietary vitamin A supplementation under HS.

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Section: Discussionsupporting

confidence: 92%

Dietary vitamin A can improve immune function in heat-stressed broilers

Niu

Wei

Liu

et al. 2009

Animal

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“…Hai et al (2000) reported that the activities of digestive enzymes trypsin, chymotrypsin and amylase were significantly reduced when animals were kept at high temperature (32°C) conditions. Heat stress also decreases the serum and liver concentrations of vitamins (C, E and A) and minerals (Fe, Zn, Se and Cr) and also influence the immune response of poultry (Donker et al, 1990). There will be an increased rate of free radical production in the body due to an increase in body temperature (Altan et al, 2000(Altan et al, , 2003 and also by increase in whole body oxygen consumption (Sen, 1995).…”

Section: Introductionmentioning

confidence: 99%

Influence of Coenzyme Q10 Supplementation in High Energy Broiler Diets on Production Performance, Hematological and Slaughter Parameters under Higher Environmental Temperature

Gopi¹,

Purushothaman²,

Purushotha³

et al. 2015

Asian J. of Animal and Veterinary Advances

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An experiment was carried out to study the effect of CoQ10 supplementation at 20 and 40 mg kgG 1 in high energy diets under higher environmental temperature. The trial was carried out with 216 days old Cobb 400 broiler chicks divided into four treatments with nine replicates containing six birds in each. The treatments include normal energy diet (NE) (G1) (as per breeder's specifications) and high energy (HE, Normal energy plus 100 kcal) diet without (G2) and with CoQ10 supplementation at 20 (G3) and 40 (G4) mg kgG 1 . The Temperature Humidity Index (THI) during the study ranged from 24.46-33.05°C. The bird's growth performance, feed intake, feed efficiency, its serum lipid, mineral profile, serum antioxidant activity, muscle lipid and CoQ10 content, slaughter parameters cost of live weight gain were studied. There was no significant difference in the body weight gain, feed intake, feed efficiency in the growth periods and slaughter parameters among the treatment groups, whereas the production score, higher intestinal length and better feed cost per kg of live weight gain was observed in NE fed groups than the other three groups. The serum and muscle lipid content was reduced and serum antioxidant activity was increased with on CoQ10 supplementation at 20 and 40 mg kgG 1 in the diet.

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“…These differences were attributed to genetic variation among the different chicken lines in terms of their immunoglobulin production and catabolic rates (Regnier et al, 1980), immune system development rate (Parmentier et al, 1996) and blood corticostemne response during heat treatment (Siegel, 1987;Hester et al, 1996). Studies dealing with sex related differences in the immune response of chickens, on the other hand, are limited, and some workers reported either non-significant (Dunnington et al, 1987) or inconsistent (Donker et al, 1990) differences between male and female birds in their response to SFU3C. However, there are also indications from other studies that female chickens were capable of producing a higher antibody response to SRBC than male chickens (Van der Zjipp and Leenstra, 1980;Leitner et al, 1989).…”

Section: Reauita and Discussionmentioning

confidence: 88%