Heat stress combined with lipopolysaccharide induces pulmonary microvascular endothelial cell glycocalyx inflammatory damage in vitro
Jiadi Chen,
Ding Chengjia,
Cao Jingjing
et al.
Abstract:Heat stroke is a life-threatening disease with high mortality rate and
unexpected complications. Vascular endothelial glycocalyx is essential
for maintaining endothelial cell structure and function as well as
preventing adhesion of inflammatory cells. Potential relationship that
underlays the imbalance in inflammation and coagulation remains elusive.
Moreover, the role of endothelial glycocalyx in heat stroke-induced
organ injury remained unclear. Heat stress and lipopolysaccharide (LPS)
are employed to constr… Show more
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