volume 285, issue 21, P15985-15993 2010
DOI: 10.1074/jbc.m110.113605
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Abstract: Heat shock proteins (HSPs) have been implicated in the activation and survival of macrophages. This study examined the role of HSP70B, a poorly characterized member of the HSP70 family, in response to oxidatively modified LDL (oxLDL) and immune complexes prepared with human oxLDL and purified human antibodies to oxLDL (oxLDL-IC) in monocytic and macrophage cell lines. Immunoblot analysis of cell lysates and conditioned medium from U937 cells treated with oxLDL alone revealed an increase in intracellular HSP70…

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