2023
DOI: 10.21203/rs.3.rs-3146304/v1
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Heat shock Complicated by Acinetobacter baumannii Pneumonia

yaqian zhu

Abstract: Heat shock can disrupt the respiratory mucosal barrier, which further results in bacterial colonization and dissemination, subsequently leading to systemic endotoxemia. Acinetobacter baumannii is a conditional pathogenic bacterium in the respiratory tract and a common causative agent of bacterial pneumonia. During heat shock, exposure to elevated temperatures disrupts the integrity of pulmonary endothelial cells and the air-blood barrier, allowing for the colonization and extensive proliferation of Acinetobact… Show more

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