Heat-sensitive moxibustion for lumbar disc herniation: a meta-analysis of randomized controlled trials

Chen, Rixin; Xiong, Jun; Chi, Zhenhai; Zhang, Bo

doi:10.1016/s0254-6272(13)60032-1

Cited by 29 publications

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“…1 2 In our clinical practice, we have discovered and reported a heat-sensitisation phenomenon during suspended moxibustion. [1][2][3][4][5][6] Patients with a wide range of diseases may become sensitised to suspended moxibustion stimulation at certain locations on the body. Unlike healthy subjects, who usually perceive only local warmth upon moxibustion, patients with heat sensitisation experience strong warmth or heat spreading around the stimulating site or penetrating into the body, which is quite frequently accompanied with pleasant feelings.…”

Section: Heat Sensitisation In Suspended Moxibustion: Featuresmentioning

confidence: 99%

Heat Sensitisation in Suspended Moxibustion: Features and Clinical Relevance

Xie¹,

Liu²,

Hou³

et al. 2013

Acupunct Med

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We have observed a ‘heat-sensitisation’ phenomenon in a large proportion of patients receiving suspended moxibustion treatment. Patients become thermally sensitised to moxibustion stimulation at certain locations on the body, indicated by sensations of strong warmth or heat penetrating into the body (heat penetration), warmth spreading around the stimulation site (heat expansion), warmth conducting in certain directions and reaching some body regions or even internal organs remote from stimulation sites (heat transmission), or other non-thermal sensations such as aching, heaviness, pressure etc. These heat-sensitised locations are not fixed, but may, during the progression of disease, dynamically change within a certain range centred on acupuncture points. Each condition seems to have its specific set of such sensitised acupuncture points and such phenomena are not commonly observed in other body regions or in healthy subjects. A number of clinical trials have shown that the appearance of heat sensitisation is correlated with better therapeutic effects in various diseases, indicating the clinical significance of such responses. Further investigation is required to elucidate the epidemiological characteristics and biological mechanisms of the heat sensitisation in suspended moxibustion.

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Section: Heat Sensitisation In Suspended Moxibustion: Featuresmentioning

confidence: 99%

Heat Sensitisation in Suspended Moxibustion: Features and Clinical Relevance

Xie¹,

Liu²,

Hou³

et al. 2013

Acupunct Med

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“…Suspended moxibustion is commonly used, and it refers to application of the burning moxa stick on the acupuncture points at a distance. The results of a recent meta-analysis of six randomized controlled trials (RCTs) on moxibustion for LDH manifested that moxibustion presented a favorable effect on LDH symptom scores compared with that of the drug [RR = 1.91, 95% CI (1.01, 3.60)] [9]. …”

Section: Introductionmentioning

confidence: 99%

Influence of the Deqi Sensation by Suspended Moxibustion Stimulation in Lumbar Disc Herniation: Study for a Multicenter Prospective Two Arms Cohort Study

Chen

Xiong

et al. 2013

Evidence-Based Complementary and Alternative Medicine

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Moxibustion stimulates the Deqi (Qi arrival) phenomenon. Many clinical observations have documented that the character of the Deqi was a composite heat-sensitive moxibustion sensation. In this prospective multicentre comparative observational nonrandomized study, 92 patients with moderate to severe LDH were included. This study consisted of two parallel arms (A: heat-sensitive moxibustion sensation group; B: nonheat-sensitive moxibustion sensation group). Moxibustion was applied in the following three acupuncture points simultaneously: Da Changshu (BL25), Wei Zhong (BL40), and A-Shi acupuncture point (tenderness). The adjusted mean total Modified-JOA score showed significant differences between the groups in the first week (10.32 ± 4.27 95% CI [9.23 ~ 11.40] versus control group 12.42 ± 5.02 [11.62 ~ 13.69], P = 0.03). The outcome in the second week also presented significant differences in both groups (7.62 ± 4.80 [6.46 ~ 8.77] versus 10.56 ± 4.75 [9.35 ~ 11.76], P = 0.005). Significant differences were also manifested in the follow-up period (P = 0.007). It can be inferred that the existence of the Deqi (heat-sensitive moxibustion sensation) phenomenon in the process of suspended moxibustion is closely related to the curative effect, and arrival of heat-sensitive moxibustion sensation could improve the clinical curative effect of moxibustion.

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“…A systematic review has also been published regarding the effectiveness of heat sensitive moxibustion for lumbar disc herniation. 23 However, this review is not concerned with non-specific back pain, but rather, lower back pain that is secondary to lumbar disc herniation. Therefore, the protocol described here is for the first systematic review and meta-analysis on the effectiveness and safety of any type of moxibustion treatment in non-specific lower back pain patients.…”

Section: Discussionmentioning

confidence: 99%

“…A systematic review of studies on the effectiveness of heat sensitive moxibustion treatment for a lumbar disc herniation has also been published. 23 However, as the prevalence of lower back pain that is secondary to a lumbar disc herniation (LDH) is low, it is not our target condition. Only 3-4% of patients with lower back pain who came to a primary clinic suffered from spinal stenosis or a lumbar disc herniation.…”

Section: Introductionmentioning

confidence: 99%

Effectiveness and safety of moxibustion treatment for non-specific lower back pain: protocol for a systematic review

et al. 2017

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IntroductionMany patients experience acute lower back pain that becomes chronic pain. The proportion of patients using complementary and alternative medicine to treat lower back is increasing. Even though several moxibustion clinical trials for lower back pain have been conducted, the effectiveness and safety of moxibustion intervention is controversial. The purpose of this study protocol for a systematic review is to evaluate the effectiveness and safety of moxibustion treatment for non-specific lower back pain patients.Methods and analysisWe will conduct an electronic search of several databases from their inception to May 2017, including Embase, PubMed, Cochrane Central Register of Controlled Trial, Allied and Complementary Medicine Database, Wanfang Database, Chongqing VIP Chinese Science and Technology Periodical Database, China National Knowledge Infrastructure Database, Korean Medical Database, Korean Studies Information Service System, National Discovery for Science Leaders, Oriental Medicine Advanced Searching Integrated System, the Korea Institute of Science and Technology, and KoreaMed. Randomised controlled trials investigating any type of moxibustion treatment will be included. The primary outcome will be pain intensity and functional status/disability due to lower back pain. The secondary outcome will be a global measurement of recovery or improvement, work-related outcomes, radiographic improvement of structure, quality of life, and adverse events (presence or absence). Risk ratio or mean differences with a 95% confidence interval will be used to show the effect of moxibustion therapy when it is possible to conduct a meta-analysis.Ethics and disseminationThis review will be published in a peer-reviewed journal and will be presented at an international academic conference for dissemination. Our results will provide current evidence of the effectiveness and safety of moxibustion treatment in non-specific lower back pain patients, and thus will be beneficial to patients, practitioners, and policymakers.Trial registration numberCRD42016047468 in PROSPERO 2016

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Heat-sensitive moxibustion for lumbar disc herniation: a meta-analysis of randomized controlled trials

Cited by 29 publications

References 0 publications

Heat Sensitisation in Suspended Moxibustion: Features and Clinical Relevance

Heat Sensitisation in Suspended Moxibustion: Features and Clinical Relevance

Influence of the Deqi Sensation by Suspended Moxibustion Stimulation in Lumbar Disc Herniation: Study for a Multicenter Prospective Two Arms Cohort Study

Effectiveness and safety of moxibustion treatment for non-specific lower back pain: protocol for a systematic review

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