The present research provides a numerical investigation of two dimensional nanofluid flow over an inverted cone inside a porous medium. The model is developed to incorporate non-spherical shapes of CdTe-nanoparticles in water based fluid. Simultaneous effects of pertinent parameters like volume fraction, Reynold number, Hartmann number, porosity, Grashof number, radiation parameter and Peclet number on temperature distribution and velocity profile are studied and illustrated graphically. In addition, the corresponding computational results of Nusselt number and skin frication for regulating parameters are also presented in graphs and tables. The highest Nusselt number is observed for blade-shaped CdTe particles. Furthermore, the thermal conductivity and viscosity are also calculated for non-spherical shapes of CdTe nanoparticles. The result showed that the thermal conductivity of nanofluid with blade-shaped particles is 0.94% and 1.93% greater than platelet and brick type particles. The computational results for the special case are validated by comparisons with the presented results in previous studies and the results are in perfect agreement.