Heart Transplantation Outcomes in Adults with Postpartum Cardiomyopathy

Genyk, P.A.; Liu, G.S.; Nattiv, J.; Banankhah, P.; Kingsford, P.; Li, J.P.; Wolfson, A.M.; Vucicevic, D.; DePasquale, E.C.; Vaidya, A.S.

doi:10.1016/j.healun.2020.01.868

Cited by 3 publications

(2 citation statements)

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“…The overall post-transplant survival was slightly lower in the PPCM group than other etiologies. 119…”

Section: Specific Cardiomyopathiesmentioning

confidence: 99%

“…The overall post-transplant survival was slightly lower in the PPCM group than other etiologies. 119 Subsequent pregnancy in women with a history of PPCM can lead to deterioration of LV function and symptoms. 120 The risk of relapse is higher in women with persistent LV dysfunction compared with those with recovered function and can be associated with significant decline in LVEF, clinical deterioration, and death.…”

Section: Peripartum Cardiomyopathymentioning

confidence: 99%

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Heart Failure Subtypes and Cardiomyopathies in Women

DeFilippis

Beale

Martin

et al. 2022

Circulation Research

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Heart failure affects over 2.6 million women and 3.4 million men in the United States with known sex differences in epidemiology, management, response to treatment, and outcomes across a wide spectrum of cardiomyopathies that include peripartum cardiomyopathy, hypertrophic cardiomyopathy, stress cardiomyopathy, cardiac amyloidosis, and sarcoidosis. Some of these sex-specific considerations are driven by the cellular effects of sex hormones on the renin-angiotensin-aldosterone system, endothelial response to injury, vascular aging, and left ventricular remodeling. Other sex differences are perpetuated by implicit bias leading to undertreatment and underrepresentation in clinical trials. The goal of this narrative review is to comprehensively examine the existing literature over the last decade regarding sex differences in various heart failure syndromes from pathophysiological insights to clinical practice.

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“…The overall post-transplant survival was slightly lower in the PPCM group than other etiologies. 119…”

Section: Specific Cardiomyopathiesmentioning

confidence: 99%

Section: Peripartum Cardiomyopathymentioning

confidence: 99%

Heart Failure Subtypes and Cardiomyopathies in Women

DeFilippis

Beale

Martin

et al. 2022

Circulation Research

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Reproductive health after thoracic transplantation: An ISHLT expert consensus statement

Kittleson

DeFilippis

Bhagra

et al. 2023

The Journal of Heart and Lung Transplantation

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Preparing the Heart for a New Baby: Management of Pregnancy in Heart Transplant Recipients

Hussien,

Lorente-Ros,

Lam

et al. 2024

Cardiology in Review

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Heart transplant (HT) recipients are more frequently reaching childbearing age given improvement in median survival and outcomes after HT. Although most pregnancies in HT recipients have favorable outcomes, poor fetal outcomes and maternal complications such as hypertensive disorders of pregnancy are more common in HT recipients than in the general population. In this review, we summarize the current evidence to guide the management of pregnancy in HT recipients. Preconception counseling, focused on risk stratification and optimal timing of conception, is the first important step to optimize pregnancy outcomes. During pregnancy and in the postpartum period, frequent monitoring of graft function and immunosuppressive levels is recommended. Calcineurin inhibitors and corticosteroids should be the mainstay of treatment for both prevention and treatment of graft rejection. Delivery planning should follow usual obstetric indications, preferably with vaginal delivery at term using regional anesthesia. A multidisciplinary care team should be involved in management through all stages of pregnancy to ensure success.

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Heart Transplantation Outcomes in Adults with Postpartum Cardiomyopathy

Cited by 3 publications

References 0 publications

Heart Failure Subtypes and Cardiomyopathies in Women

Heart Failure Subtypes and Cardiomyopathies in Women

Reproductive health after thoracic transplantation: An ISHLT expert consensus statement

Preparing the Heart for a New Baby: Management of Pregnancy in Heart Transplant Recipients

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