Heart transplantation: echocardiographic assessment of morphology and function after more than 10 years of follow-up

Wilhelmi, Michaela; Pethig, Klaus; Wilhelmi, Mathias; Nguyen, Hien; Strüber, Martin; Haverich, Axel

doi:10.1016/s0003-4975(02)03833-x

Cited by 31 publications

(28 citation statements)

References 19 publications

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“…The effect was also significant in the subgroup of HTx patients, but again, due to the limited N, this hypothesis could not be tested in the subgroup of LuTx. Observational studies suggest that normal LVEF is preserved in the majority of long-term HTx survivors [22,23] . There have been conflicting reports on the predictive value of LVEF in HTX patients without ESRD [24][25][26][27] .…”

Section: Discussionmentioning

confidence: 99%

Risk Stratification for Renal Transplantation after Cardiac or Lung Transplantation: Single-Center Experience and Review of the Literature

Rosenberger¹,

Stein²,

Jürgensen³

et al. 2007

Kidney Blood Press Res

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Background: Long-term survival after heart (HTx) or lung (LuTx) transplantation increases the risk for end-stage renal disease (ESRD). After HTx ESRD was reported to enhance mortality, and kidney transplantation (KTx) was shown to improve survival. However, prognostic factors in ESRD after HTx or LuTx are largely unknown. Methods: Single-center observational study in HTx and LuTx patients who accessed the KTx waiting list; baseline characteristics were correlated with mortality. Results: KTx was performed in 15 of 65 study patients. Survival was comparable on the KTx waiting list and in reference patients from the same center without ESRD. KTx significantly improved survival (5 years’ survival 84.6% with KTx vs. 56.5% on the KTx waiting list, p = 0.030). None of the baseline parameters predicted mortality in the KTx group. Only on the KTx waiting list BMI (median 24.7 vs. 20.7; p < 0.05) and left ventricular ejection fraction (LVEF, median 63 vs. 53%, p < 0.008) significantly correlated with survival. Conclusions: The risk for mortality after HTx or LuTx is not increased by ESRD, provided that patients meet access criteria for the KTx waiting list. KTx improves survival in ESRD after HTx or LuTx. BMI and LVEF may predict outcome in HTx/LuTx patients on the KTx waiting list.

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Section: Discussionmentioning

confidence: 99%

Risk Stratification for Renal Transplantation after Cardiac or Lung Transplantation: Single-Center Experience and Review of the Literature

Rosenberger¹,

Stein²,

Jürgensen³

et al. 2007

Kidney Blood Press Res

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show abstract

“…The overall prevalence ranges from 47 to 98% in echocardiographic series. But severe TR occurs rarely and is refractory to medical management [1,8,10,24]. DeSimone reports that TR can occur immediately after transplantation and can be caused in turn by a reduction in systolic annulus shortening.…”

Section: Significance Of Tricuspid Regurgitationmentioning

confidence: 99%

“…In almost all patients undergoing tricuspid valve replacement reported ruptured or torn chordae were identified at the time of operation, further supporting the theory that severe TR is biopsy induced. The chordae tendineae usually arise from the papillary muscles but also from the septal wall and thus are subject to trauma by the biotome each time it traverses the tricuspid valve [8,24]. The influence of number and degree of rejection episodes on the incidence of TR is discussed controversely [2,8].…”

Section: Explanation Of Trmentioning

confidence: 99%

“…Apart from a distortion of the tricuspid annulus due to disturbed geometry of the right atrial anastomosis, there might be an influence of ischemic injury to the papillary muscles at the time of transplantation [1,24,25].…”

Section: Explanation Of Trmentioning

confidence: 99%

“…Increased late diastolic tricuspid flow in the patient with bicaval technique indicated more rigorous RA contraction following by better atrial relaxation. RA contraction may be less vigorous in recipients of the standard technique as a result of atrial sutures and greater size [3,24].…”

Section: Right Atrial Functionmentioning

confidence: 99%

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