Heart Transplantation During Active Infective Endocarditis: Case Report and Review of the Literature

Durante‐Mangoni, Emanuele; Casillo, Roberta; Pinto, Daniela Di; Caianiello, C.; Albisinni, Rosina; Caprioli, V.; Maiello, Ciro; Utili, Riccardo

doi:10.1016/j.transproceed.2010.09.095

Cited by 12 publications

(14 citation statements)

References 14 publications

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“…If heart transplantation is considered as a curative approach in patients who failed medical or surgical treatment, SOT can be considered as soon as cultures are sterile…”

Section: Resultsmentioning

confidence: 99%

“…In the case of bacterial endocarditis, 64% of panel members recommended an intermediate delay and 36% a prolonged delay (C; 2) (Table ) . Respondents indicated the importance of the urgency of transplant, patient stability, and microorganism virulence.…”

Section: Resultsmentioning

confidence: 99%

“…( Table 3). [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17] Respondents indicated the importance of the urgency of transplant, patient stability, and microorganism virulence. In the case of VAD infection, there was no consensus among the panel members and answers were equally distributed between brief, intermediate, and prolonged delay (A/B/C; 3).…”

Section: Ta B L E 3 (Continued)mentioning

confidence: 99%

“…With respect to Candida bloodstream infections, the panel's opinions were equally divided between brief and intermediate delay (B/C; 3) (Table 3). 3,6,9,[17][18][19][20][21][22][23][24] . Respondents suggested that the urgency…”

Section: Invasive Candidiasismentioning

confidence: 99%

“…Recommendations and percentage agreement for other bacterial and fungal infections Some centers postpone SOT for >2 wk after documentation of negative blood cultures when possible. If SOT is urgent, SOT can occur as soon as blood culturesare sterileIf heart transplantation is considered as a curative approach in patients who failed medical or surgical treatment,3 SOT can be considered as soon as cultures are The European Association of Urology recommends treating the UTI and resolving predisposing factors such as obstruction, reflux, or infection focus before kidney There is debate about contraindication for lung transplant in cases of MDR bacteria such as B cenocepacia 9,10. The AST-IDCOP recommends documenting microbiological (at least negative AFB stains) and radiographic resolution before SOT unless risks outweigh benefits, especially because of challenges of TB treatment after SOT such as potential disease severity and interactions between immunosuppressants and antibacterials 11,12.…”

mentioning

confidence: 99%

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Infections among pediatric transplant candidates: An approach to decision‐making

L’Huillier

Green

Danziger‐Isakov

et al. 2019

Pediatric Transplantation

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Introduction The presence of infections in the immediate pretransplant period poses challenges in decision‐making. Delaying transplantation because of these infections may be required, but is associated with a risk to the potential recipient. The aim of this project was to develop a structured framework based on expert opinion to guide decision‐making regarding the safety of transplantation for candidates with infection immediately before transplant, and to show how this framework can be applied to clinical scenarios. Methods Categories were created as follows: Category A: no delay; Category B: brief delay (≤1 week); Category C: intermediate delay (>1 week); and Category D: more prolonged or indefinite delay. A survey containing 59 clinical scenarios was sent to members of the IPTA ID CARE committee. Answers were reviewed, and the level of agreement was characterized as follows: Level 1: ≥75% agreement; Level 2:51%‐74% agreement; and Level 3: ≤50% agreement. 95% CIs were calculated for the mean overall agreement across 59 scenarios. Results Among the panel, the agreement level ranged from 33% to 92% with the mean overall agreement across the 59 scenarios being 61%. For 7/59 scenarios, the lower bound of 95% CI was greater than 50%, indicating a difference at the 5% level of significance between the observed proportion and the chance level of 0.5. Summary The document provides expert opinion regarding the need to delay transplantation in the setting of different infections. The most important points in the decision to proceed to SOT included the urgency of transplantation and the severity of infection.

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“…If heart transplantation is considered as a curative approach in patients who failed medical or surgical treatment, SOT can be considered as soon as cultures are sterile…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%