Heart Regeneration

Seliktar, Dror; Berdichevski, Alexandra; Mironi‐Harpaz, Iris; Shapira-Schweitzer, Keren

doi:10.1016/b978-0-12-398523-1.00030-6

Cited by 2 publications

(1 citation statement)

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“…Biomaterial-based cardiac cell therapy has been developed to enhance cell survival and contractility of the infarcted myocardium. This includes the use of tissue-engineered cardiac patches and injectable biomaterial/cell grafts [ 21 ]. Furthermore, research exploring PRP therapy has demonstrated a reduction in infarct size and the prevention of scar tissue formation.…”

Section: Reviewmentioning

confidence: 99%

Platelet-Rich Plasma for Heart Cell Regeneration Post-myocardial Infarction: A Propitious Therapeutic Approach

Navab,

Haward,

Chacko

et al. 2024

Cureus

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Globally, one of the primary factors leading to death is cardiovascular disorders, specifically coronary artery disease, which leads to myocardial infarction (MI). This article investigates the potential of platelet-rich plasma (PRP) therapy for regenerating cardiac cells following MI. We look into the pathophysiology of MI, current treatment methods, and the heart's limited ability to heal itself. This is done to see if PRP could help the heart heal faster, reduce the size of the infarct, and stop scar tissue from forming. We analyze the production procedure of PRP, its composition of growth factors, and its utilization in many medical domains. The ways that PRP helps the heart heal are also being looked into. This includes how it affects inflammation, oxidative stress, angiogenesis, and cell proliferation. Although we recognize the existing constraints, we meticulously take into account issues such as standardization, therapeutic variance, and potential harmful effects. This study highlights the importance of comprehensive guidelines, continuous research, and enhanced clinical applications to fully harness the potential of platelet-rich plasma in the regeneration of cardiac cells after a heart attack.

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Section: Reviewmentioning

confidence: 99%