Heart Rate Variability Reproducibility and Stability Using Commercially Available Equipment in Coronary Artery Disease With Daily Life Myocardial Ischemia**This work was supported in part by grants from the Division of Cardiology, Department of Medicine, Cedars-Sinai Medical Center, the John D. and Catherine T. MacArthur Foundation, Grant HL47337 from the National Institutes of Health, and Marquette Electronics Inc.

Pardo, Y; Merz, C. Noel Bairey; Paul-Labrador, Maura; Velasquez, Ivan; Gottdiener, John S.; Kop, Willem J.; Krantz, David S.; Rozanski, Alan; Klein, Jacob; Peter, Thomas

doi:10.1016/s0002-9149(96)00458-4

Cited by 37 publications

(5 citation statements)

References 29 publications

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“…A growing exploration of patterns of variation or fluctuations in physiologic time series, particularly heart rate variability (HRV) analysis, has been shown to provide clinically useful and otherwise 'hidden' information about the health of the system producing the dynamics. For example, Fourier spectral analysis of heart rate (HR) data has shown that frequency profiles characterizing HRV are altered during illness and that the degree of alteration of these frequency profiles correlates with illness severity in conditions ranging from hypovolaemia [25] to heart failure [26-28], from hypertension [29,30] to coronary artery disease [31,32] and from angina [33] to myocardial infarction [34]. These studies demonstrate that HRV is consistently and reproducibly altered in illness, and the degree of HRV alteration is prognostic of illness severity.…”

Section: Introductionmentioning

confidence: 99%

Clinical review: A review and analysis of heart rate variability and the diagnosis and prognosis of infection

et al. 2009

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Bacterial infection leading to organ failure is the most common cause of death in critically ill patients. Early diagnosis and expeditious treatment is a cornerstone of therapy. Evaluating the systemic host response to infection as a complex system provides novel insights: however, bedside application with clinical value remains wanting. Providing an integrative measure of an altered host response, the patterns and character of heart rate fluctuations measured over intervals-in-time may be analysed with a panel of mathematical techniques that quantify overall fluctuation, spectral composition, scale-free variation, and degree of irregularity or complexity. Using these techniques, heart rate variability (HRV) has been documented to be both altered in the presence of systemic infection, and correlated with its severity. In this review and analysis, we evaluate the use of HRV monitoring to provide early diagnosis of infection, document the prognostic implications of altered HRV in infection, identify current limitations, highlight future research challenges, and propose improvement strategies. Given existing evidence and potential for further technological advances, we believe that longitudinal, individualized, and comprehensive HRV monitoring in critically ill patients at risk for or with existing infection offers a means to harness the clinical potential of this bedside application of complex systems science.

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Section: Introductionmentioning

confidence: 99%

Clinical review: A review and analysis of heart rate variability and the diagnosis and prognosis of infection

et al. 2009

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“…Earlier reproducibility studies have focused on healthy subjects and other kinds of patient populations (Carrasco et al 2003;Marks and Lightfoot 1999;Pardo et al 1996;Sandercock et al 2004;Schroeder et al 2004;Sinnreich et al 1998;Tarkiainen et al 2005). This study is a sequel to an earlier study that used the same device to measure HRV and RR in healthy subjects (Guijt et al 2007).…”

Section: Discussionmentioning

confidence: 97%

Reproducibility and validity of heart rate variability and respiration rate measurements in participants with prolonged fatigue complaints

Sluiter

Guijt

Frings‐Dresen

2008

Int Arch Occup Environ Health

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“…Participation in the cardiac rehabilitation exercise program was assessed by enrollment. The blood pressure protocol included 5 minutes of sitting quietly followed by three blood pressure measurements at one-minute intervals using a mercury sphygmomanometer, and then averaged for screening, entry and exit visits [12, 13]. Body weight and height were measured to the nearest 0.1 kg and 0.1 cm, and body mass index (BMI) calculated (kg/m 2 ).…”

Section: Methodsmentioning

confidence: 99%

“…Holter monitoring was recorded and analyzed during a 24-hour period and during provocative testing using our previously validated and published methods [13]. A 24-hour recording was considered eligible for this study if it had more than 12 hours of analyzable data, had half of the nighttime and daytime periods analyzable, and if more than 50% of the recording revealed sinus rhythm.…”

Section: Methodsmentioning

confidence: 99%

A randomized controlled trial of acupuncture in stable ischemic heart disease patients

Mehta

Polk

Xiao

et al. 2014

International Journal of Cardiology

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Background Heart rate variability (HRV) is reduced in stable ischemic heart disease (SIHD) patients and is associated with sudden cardiac death (SCD). We evaluated the impact of traditional acupuncture (TA) on cardiac autonomic function measured by HRV in SIHD patients. Methods We conducted a randomized controlled study of TA, sham acupuncture (SA), and waiting control (WC) in 151 SIHD subjects. TA group received needle insertion at acupuncture sites, SA group received a sham at non-acupuncture sites, while WC received nothing. TA and SA received 3 treatments/week for 12 wks. 24-hour, mental arithmetic stress, and cold pressor (COP) HRV was collected at entry and exit, along with BP, lipids, insulin resistance, hs-CRP, salivary cortisol, peripheral endothelial function by tonometry(PAT), and psychosocial variables. Results Mean age was 63±10; 50% had prior myocardial infarction. Comparison of WC and SA groups demonstrated differences consistent with the unblinded WC status; therefore by design, the control groups were not merged. Exit mental stress HRV was higher in TA vs. SA for markers of parasympathetic tone (p≤0.025), including a 17% higher vagal activity (p=0.008). There were no differences in exit 24-hour or COP HRV, BP, lipids, insulin resistance, hs-CRP, salivary cortisol, PAT, or psychosocial variables. Conclusions TA results in intermediate effects on autonomic function in SIHD patients. TA effect on HRV may be clinically relevant and should be explored further. These data document feasibility and provide sample size estimation for a clinical trial of TA in SIHD patients for prevention of SCD.

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Cited by 37 publications

References 29 publications

Clinical review: A review and analysis of heart rate variability and the diagnosis and prognosis of infection

Clinical review: A review and analysis of heart rate variability and the diagnosis and prognosis of infection

Reproducibility and validity of heart rate variability and respiration rate measurements in participants with prolonged fatigue complaints

A randomized controlled trial of acupuncture in stable ischemic heart disease patients

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