Heart Rate Variability in Women with Systemic Lupus Erythematosus: Association with Health-Related Parameters and Effects of Aerobic Exercise

Abstract

Abnormal heart rate variability (HRV) has been observed in patients with systemic lupus erythematosus (SLE). In a combined cross-sectional and interventional study approach, we investigated the association of HRV with inflammation and oxidative stress markers, patient-reported outcomes, and the effect of 12 weeks of aerobic exercise in HRV. Fifty-five women with SLE (mean age 43.5 ± 14.0 years) were assigned to either aerobic exercise (n = 26) or usual care (n = 29) in a non-randomized trial. HRV was assessed using a heart rate monitor during 10 min, inflammatory and oxidative stress markers were obtained, psychological stress (Perceived Stress Scale), sleep quality (Pittsburg Sleep Quality Index), fatigue (Multidimensional Fatigue Inventory), depressive symptoms (Beck Depression Inventory), and quality of life (36-item Short-Form Health Survey) were also assessed. Low frequency to high frequency power (LFHF) ratio was associated with physical fatigue (p = 0.019). Sample entropy was inversely associated with high-sensitivity C-reactive protein (p = 0.014) and myeloperoxidase (p = 0.007). There were no significant between-group differences in the changes in HRV derived parameters after the exercise intervention. High-sensitivity C-reactive protein and myeloperoxidase were negatively related to sample entropy and physical fatigue was positively related to LFHF ratio. However, an exercise intervention of 12 weeks of aerobic training did not produce any changes in HRV derived parameters in women with SLE in comparison to a control group.

Oxidative and antioxidative stress markers in dry eye disease: A systematic review and meta‐analysis

“…However, evidence data showed that systemic auto-immune disease as Sj€ ogren syndrome increase the levels of oxidative stress markers with severe repercussions on organs and organism (i.e. lipid metabolism, cardiovascular system, osteoarticular dysfunctions and exocrine functions) (Smallwood et al 2018;Charras et al 2019;Hu et al 2020;Mart ınez-Rosales et al 2020). Even if ageing decreases the antioxidative defences on ocular surface (Choy, Cho & Benzie 2011), we did not show any influence of age in oxidative stress homeostasis.…”

“…2020; Martínez‐Rosales et al. 2020). Even if ageing decreases the antioxidative defences on ocular surface (Choy, Cho & Benzie 2011), we did not show any influence of age in oxidative stress homeostasis.…”

Effects on Heart Rate Variability of Stress Level Responses to the Properties of Indoor Environmental Colors: A Preliminary Study

“…They were asked to abstain from consuming alcohol and take a >6 h nap before the experiment. Additionally, caffeine consumption was restricted 3 h before the test [38], and the Ishihara test was administered to the participants for testing color blindness or color weakness [3]. Before the experiment, the subjects were directed to conduct a self-diagnosis of their health, and they were found to have a good health condition without any particular health problems.…”

Determination of heart rate variability as an indicator of the influence of the tone of the autonomic nervous system in goats

“…Під її дією зменшується активність серцевосудинної системи, переважають процеси травлення та синтезу поживних речовин. У зв'язку з тим, що кожна тварина має індивідуальні особливості організму, вплив вищенаведених відділів може різнитися (Quevedo et al, 2019;Martínez-Rosales et al, 2020).…”

“…Для діагностики стану тварини часто використовували аналіз частоти серцевих скорочень під час доїння або дії больового фактору. З часом постало питання кращого аналізу серцевосудинної системи для дослідження впливу стресу на кіз (Kovács et al, 2019;Martínez-Rosales et al, 2020). Варіабельність серцевого ритму відображує активність автономної нервової системи в організмі.…”