Heart rate recovery post 6-minute walking test in obstructive sleep apnea

Cholidou, Kyriaki; Manali, Effrosyni D.; Kapsimalis, Fotis; Kostakis, Ioannis D.; Vougas, Konstantinos; Simoes, Davina Camargo Madeira; Markozannes, Evangelos; Vogiatzis, Ioannis; Bakakos, Petros; Koulouris, Nikolaos; Alchanatis, Manos

doi:10.1007/s00392-014-0721-3

Cited by 14 publications

(11 citation statements)

References 39 publications

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“…In this context, it is known that the severity of COPD, as well as the severity of OSAS, is closely associated with impairments in functional capacity. 21 In the present study, only SDNN and SD2 (both representative of total HRV) were sensitive to HRV reduction during exercise. As for the other indexes, we did not observe any differences during walking.…”

Section: Discussionmentioning

confidence: 45%

Chronic obstructive pulmonary disease severity and its association with obstructive sleep apnea syndrome: impact on cardiac autonomic modulation and functional capacity

Zangrando¹,

Trimer²,

Carvalho³

et al. 2018

COPD

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BackgroundThe study was conducted to determine the impact of chronic obstructive pulmonary disease (COPD) in association with obstructive sleep apnea syndrome (OSAS) on cardiac autonomic control and functional capacity.Subjects and methodsThe study was a cross-sectional prospective controlled clinical study. Heart rate variability indices of 24 COPD (n = 12) and COPD+OSAS (n = 12) patients were evaluated and compared by electrocardiographic recordings acquired during rest, active postural maneuver (APM), respiratory sinus arrhythmia maneuver (RSA-m), and the 6-minute walk test (6MWT).ResultsThe COPD group presented higher parasympathetic modulation during APM when compared to the COPD+OSAS group (P = 0.02). The COPD+OSAS group presented higher sympathetic modulation during RSA-m when compared to the COPD group (P = 0.00). The performance during 6MWT was similarly impaired in both groups, despite the greater severity of the COPD group.ConclusionSubjects with COPD+OSAS present marked sympathetic modulation, and the presence of OSAS in COPD subjects has a negative impact on functional capacity regardless of the severity of lung disease.

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Section: Discussionmentioning

confidence: 45%

Chronic obstructive pulmonary disease severity and its association with obstructive sleep apnea syndrome: impact on cardiac autonomic modulation and functional capacity

Zangrando¹,

Trimer²,

Carvalho³

et al. 2018

COPD

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“…For instance, in a series of patients with pulmonary arterial hypertension, impaired HRR, defined as a <16 beatdecrease at 1 min following the 6MWT, was found to be prognostic of clinical worsening (hazard ratio, 5.2; 95% CI, 1.8 to 14.8) [34]. Impaired HRR has also been shown to be predictive of the severity of apnea in patients with obstructive sleep apnea [35,36] and functional capacity in long-term survivors of pulmonary embolism [37]. The ANS, therefore, plays an important role in both cardiovascular and respiratory disorders.…”

Section: Hrr In Respiratory Diseasementioning

confidence: 96%

Heart Rate Recovery as a Preoperative Test of Perioperative Complication Risk

Fuster

Ries

et al. 2015

The Annals of Thoracic Surgery

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The autonomic nervous system plays important physiologic roles in a variety of organ systems. Autonomic dysfunction has been shown to be predictive of increased mortality in patients with cardiovascular disease. Its importance in patients with chronic respiratory disorders has been described in recent years. Here, we summarize the prognostic value of autonomic dysfunction, as reflected by impaired heart rate recovery (HRR), in patients with chronic respiratory disorders, including chronic obstructive pulmonary disease, interstitial lung disease, and lung cancer. We suggest that HRR may be clinically useful in the preoperative physiologic evaluation, specifically in lung cancer patients being considered for surgery.

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“…Such dynamics have been previously reported in regard to comparison of healthy vs clinical, and specifically in regard to people with OSA. [50][51][52][53][54][55] Sixteen weeks of exercise improved heart at rest and responses during exercise in the subjects with OSA. Such improvement to heart rate were previously noted in the literature.…”

Section: Heart Ratementioning

confidence: 99%