Heart rate changes during partial seizures: A study amongst Singaporean patients

Abstract

Introduction: Studies in Europe and America showed that tachycardia, less often bradycardia, frequently accompanied partial seizures in Caucasian patients. We determine frequency, magnitude and type of ictal heart rate changes during partial seizures in non-Caucasian patients in Singapore.

Pre-ictal heart rate changes: A systematic review and meta-analysis

“…Thirty studies, enrolling 1110 people living with epilepsy (39.0% female; 38.2% male; 22.8% not reported) and a total of 2957 seizures, assessed the occurrence of pre-ictal HRI. Eighteen included adults [12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29], four children only [29][30][31][32][33], and seven both adults and children [34][35][36][37][38][39][40]. The age group was not reported in one study [41].…”

Ictal asystole with convulsive syncope mimicking secondary generalisation: a depth electrode study

“…[5][6][7] Furthermore, the localising value of bradycardia and asystole is still debated, 1 since some small series or case reports 6 8-11 postulated an association with left temporal seizures, whereas other authors did not confirm this. [12][13][14][15] Pathophysiologically, cerebral hypoperfusion induces loss of consciousness, at times with myoclonic jerks (convulsive syncope). Differentiation of the latter from a generalised convulsive seizure may prove to be difficult even for experienced clinicians.…”

A new algorithm for detection of epileptic seizures based on HRV signal

“…Different mechanisms are implicated in the generation of ictal HR changes in epileptic patients. Increased adrenergic activities during seizures have been observed in animals (Wilder-Smith & Lim, 2001) and may account for ictal tachy-arrhythmias being much more common than bradyarrhythmias. Studies on the incidence of ictal HR changes report tachycardia in over 90% of partial seizures depending on the criteria used for tachycardia (Wilder-Smith & Wilder-Smith, 1995).…”

“…Previous research showed different behaviours in epileptic seizures and the symptoms of tachycardia, bradycardia, fluctuation and the arrhythmia might be occurring in different types of seizures (Goldberger, 1999;Mohanraj et al, 2006;Nobili et al, 2010;Schanabel, Beblo, May, & Burmester, 2002;Stöllberger & Finsterer, 2004;Surges, Scott, & Walker, 2010;Tinuper et al, 2001;Walczak et al, 2001;Wilder-Smith & Lim, 2001). Therefore, to better evaluate the classifiers, the classifications were performed separately for each type of the seizures (SG and CP seizures).…”