Heart Rate and Blood Pressure Changes During Autonomic Nervous System Challenge in Panic Disorder Patients

Abstract

These findings demonstrate a consistently higher or deregulated autonomic arousal in PD patients at rest and during orthostatic challenge compared with HC. These data also reveal a possible association between the level of anxiety illness severity and sympathovagal balance, which may imply greater cardiac risk.

Cardiorespiratory response to physical exercise and psychological variables in panic disorder

“…This suggests that the poor fitness condition of patients with PD might be related to an actual malfunction of their cardiorespiratory system, causing patients to be less able to cope with physical perturbations; this may be partly due to the pathophysiology of PD and contribute to the cardiovascular morbidity of PD patients. 13 However, other possible explanations may account for our results. First, the sample size was very small, limiting the study´s power to show significant associations and, although patients and controls were matched for sport activities, it is possible that the poorer fitness conditioning seen in patients with PD might be related to avoidance behaviours and reduced outdoors activities.…”

“…Considering the small size of our sample, our results have confirmed previous findings on the poor fitness condition of Table 1 Heart rate, anxiety, and subjective exertion during the procedure; psychological variables Values are expressed as mean (SD); HR: Heart rate (beats/minute); HR 3%-21%: Heart rate at the different increasing slopes; M HR: Heart rate at half maintenance phase (between 65% and 75% of rest HR); HS HR: Heart rate at half of the maximum slope; HR recovery 0%: Heart rate at 0% slope; patients with PD 1-3 and, in parallel, previous results of their abnormal cardiorespiratory function, including sensation of "respiratory effort", 12 decreased heart-rate variability, 13 and malfunction of autonomic system. 13 Moreover, we found that their poor cardiorespiratory response and low exercise tolerance did not appear to be related to anxiety levels before or during exercise, trait anxiety, fear of physical sensations, or fear of autonomic arousal.…”

“…13 Moreover, we found that their poor cardiorespiratory response and low exercise tolerance did not appear to be related to anxiety levels before or during exercise, trait anxiety, fear of physical sensations, or fear of autonomic arousal. This suggests that the poor fitness condition of patients with PD might be related to an actual malfunction of their cardiorespiratory system, causing patients to be less able to cope with physical perturbations; this may be partly due to the pathophysiology of PD and contribute to the cardiovascular morbidity of PD patients.…”

1120 Effects of Post-Exposure Naps on Change in Autonomic Arousal to A social Challenge Across Exposure Therapy for Social Anxiety

“…Previous studies (Garakani et al, 2009;Martinez, Garakani, Kaufmann, Aaronson, & Gorman, 2010) found a significantly lowered pNN50% in panic disorders relative to controls, suggesting that more anxiety caused a decrease in pNN50%. This study also found a significant increase of the pNN50 from the post-compared to the pretreatment mpTSST, showing that participants had lower levels of anxiety during the posttreatment mpTSST.…”

Postural Orthostatic Tachycardia Syndrome (POTS): Assess, Diagnose, and Evaluate for POTS Treatment (ADEPT)

“…When studying the ANS with respect to stress, it is the SNS that is associated with an increased heart rate [21]. The function of the parasympathetic nervous system (PSNS) for recovery is recognized by looking at the sensitive beat-to-beat parameters of heart rate variability (HRV), particularly the high-frequency (HF) measures [21].…”