Hearing Rehabilitative Treatment for Older Adults With Comorbid Hearing Loss and Depression: Effects on Depressive Symptoms and Executive Function

Brewster, Katharine K.; Choi, C. Jean; He, Xiaofu; Kim, Ana H.; Golub, Justin S.; Brown, Patrick J.; Liu, Ying; Roose, Steven P.; Rutherford, Bret R.

doi:10.1016/j.jagp.2021.08.006

Cited by 10 publications

(28 citation statements)

References 45 publications

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“…In a subsequent trial of N = 25 participants, we found that hearing aids were associated with improvements in executive and episodic memory functioning 17 . While hearing aid treatment was effective in improving hearing functioning in this study, no significant effect of treatment on the primary depression outcome was observed 17 …”

Section: Introductionmentioning

confidence: 49%

“…In the first study of N = 13 participants with MDD and HL, we found that treatment with hearing aids (vs. sham) was associated with greater improvement in depressive symptoms and immediate recall on a measure of episodic memory functioning 16 . In a subsequent trial of N = 25 participants, we found that hearing aids were associated with improvements in executive and episodic memory functioning 17 . While hearing aid treatment was effective in improving hearing functioning in this study, no significant effect of treatment on the primary depression outcome was observed 17 …”

Section: Introductionmentioning

confidence: 86%

“…Effects of hearing aid treatment on depressive and cognitive outcomes in both studies were previously published. 16,17 For the combined sample of N = 37 participants, hearing aid treatment as opposed to sham was associated with a 3.98-point improvement on HRSD (active −9.72 vs. sham −5.74, t = 1.92, df = 205, p = 0.0562).…”

Section: Hearing Aid Treatment Effects On Depressionmentioning

confidence: 98%

See 2 more Smart Citations

A precision medicine tool to understand who responds best to hearing aids in late‐life depression

Brewster

Zilcha‐Mano

Wallace

et al. 2022

Int J Geriat Psychiatry

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Objectives Accumulating evidence suggests that hearing loss (HL) treatment may benefit depressive symptoms among older adults with Major Depressive Disorder (MDD), but the specific individual characteristics of those who stand to improve most are unknown. Methods N = 37 patients ≥60 years with HL and MDD received either active or sham hearing aids in this 12‐week double‐blind randomized controlled trial. A combined moderator approach was utilized in the analysis in order to examine multiple different pretreatment individual characteristics to determine the specific qualities that predicted the best depressive symptom response to hearing aids. Pretreatment characteristics included: Hearing Handicap Inventory for the Elderly (HHIE‐S), pure tone average (PTA), speech reception threshold (SRT), Short Physical Performance Battery (SPPB), cognition (Repeatable Battery for the Assessment of Neuropsychological Status). Results The analysis revealed a combined moderator, predicting greater improvement with active versus sham hearing aids, that had a larger effect size than any individual moderator (combined effect size [ES] = 0.49 [95% CI: 0.36, 0.76]). Individuals with worse hearing‐related disability (HHIE‐S: individual ES = −0.16), speech recognition (SRT: individual ES = −0.14), physical performance (SPPB: individual ES = 0.41), and language functioning (individual ES = 0.19) but with relatively less severe audiometric thresholds (PTA: individual ES = 0.17) experienced greater depressive symptom improvement with active hearing aids. Conclusions Older adults with relatively worse HL‐related, physical, and cognitive functioning may stand to benefit most from hearing aids. Given the large number of older adults experiencing HL and MDD, a non‐invasive and scalable means of targeting those most likely to respond to interventions would be valuable.

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Section: Introductionmentioning

confidence: 49%

Section: Introductionmentioning

confidence: 86%

Section: Hearing Aid Treatment Effects On Depressionmentioning

confidence: 98%

See 1 more Smart Citation

A precision medicine tool to understand who responds best to hearing aids in late‐life depression

Brewster

Zilcha‐Mano

Wallace

et al. 2022

Int J Geriat Psychiatry

Self Cite

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“…The results on the effects of hearing aids on broader health outcomes such as mental health, physical health, cognitive function, and social engagement are also inconsistent to some degree. On the one hand, studies found that those using hearing aids had no significant improvement in mental health, cognitive function, social participation, or quality of life compared with the non-users [ 21 – 23 ]. On the other hand, some believed that hearing aid users had a significant decline in perceptions of loneliness, improved social skills, better self-care and daily activities, and better general health [ 24 , 25 ].…”

Section: Introductionmentioning

confidence: 99%

“…One epidemiological study using data from the National Health and Nutrition Examination Survey (NHANES) found that hearing aid use is independently associated with reduced odds of major depressive disorder and depressive symptoms [ 11 ]. In addition, improvements in social engagement, mental health, and cognitive processing has been reported in those using hearing aids [ 16 , 21 ].…”

Section: Introductionmentioning

confidence: 99%

Effects of providing free hearing aids on multiple health outcomes among middle-aged and older adults with hearing loss in rural China: a randomized controlled trial

Zhu

Chen

et al. 2022

BMC Med

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Background Hearing loss has been associated with serious health problems around the globe. Previous studies have found the positive effects of fitting hearing aids on health, but few studies were conducted in developing countries. The aim of this study is to examine the effects of hearing aids on multiple health outcomes among middle-aged and older adults with hearing loss in rural China. Methods In this randomized controlled trial (RCT), participants aged 45 and above were randomly assigned to the treatment group prescribing with hearing aids or to the control group with no intervention. Trial outcomes for 385 participants were collected during the 20-month follow-up study. Using the difference-in-difference approach, our primary outcomes were hearing-related quality of life (QoL) and generic QoL. Results The intervention led to improvements in hearing-related QoL, presenting as the reduction in Hearing Handicap Inventory for the Elderly Screening Version (HHIE-S) scores (interaction coefficient = − 2.86, p = 0.005), HHIE-S-Emotional scores (interaction coefficient = − 1.42, p = 0.029), and HHIE-S-Situational scores (interaction coefficient = − 1.43, p = 0.007). The intervention was also effective in alleviating the increase in depressive symptoms (interaction coefficient = − 0.14, p = 0.042). Subgroup analysis revealed that the effects were only shown among people with social activities or active social networks. Conclusions Our study is the first RCT in China to measure the health effects and heterogeneity of hearing aid interventions. Wearing hearing aids can help improve hearing-related QoL and alleviate the increase in depressive symptoms. The intervention is expected to be applicable to similar settings in other developing countries to combat hearing-related health problems. Trial registration Chinese Clinical Trial Registry, ChiCTR1900024739. Registered on 26 July 2019.

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Hearing Management as a Therapeutic Agent for Depression: A New Consideration

Powell

2022

The American Journal of Geriatric Psychiatry

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Hearing Rehabilitative Treatment for Older Adults With Comorbid Hearing Loss and Depression: Effects on Depressive Symptoms and Executive Function

Cited by 10 publications

References 45 publications

A precision medicine tool to understand who responds best to hearing aids in late‐life depression

A precision medicine tool to understand who responds best to hearing aids in late‐life depression

Effects of providing free hearing aids on multiple health outcomes among middle-aged and older adults with hearing loss in rural China: a randomized controlled trial

Hearing Management as a Therapeutic Agent for Depression: A New Consideration

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