Hearing Problems Subsequent to Neonatal Hemolytic Disease or Hyperbilirubinemia

Keaster, Jacqueline

doi:10.1001/archpedi.1969.02100030408003

Cited by 7 publications

(6 citation statements)

References 4 publications

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“…Similar to other aminoglycosides, KM is ototoxic and may cause irreversible damage to the hair cells of the cochlea. However, when treating neonatal infections with KM in a dose of [10][11][12][13][14][15] mg/kg/24 h for 5-10 days, no ototoxic effect was observed according to follow-up investigations of 4-to 6-year-old children by Eichenwald (7), Fujii (9) and Sanders et al (12).…”

mentioning

confidence: 99%

Possible Effects of Kanamycin and Incubation in Newborn Children With Low Birth Weight

et al. 1978

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In an acoustico-vestibular follow-up investigation of 91 four- to six-year-old children with birth weight below 2000 g, the same incidence of sensorineural hearing loss (19%) was found in 54 children treated with kanamycin in the neonatal period as in a group of 37 infants not treated with kanamycin. When comparing a group of children treated with both kanamycin and incubator (54 children) with a group treated with incubator only (16 children), no definite signs of synergism between incubator noise and kanamycin were found. However, the 5 cases of moderate or severe hearing loss all belonged to the group treated with both incubator and kanamycin. These 5 children had more severe neonatal complications, especially apnea, cyanotic spells and hyperbilirubinemia, which may increase the severity of the hearing loss. Among 56 incubator treated children with normal hearing (ISO standards) 52% had an audiogram pattern suggesting minor noise-provoked cochlear lesions. Among 18 non-incubator treated children with normal hearing only one child (6%) had a similar pattern. It should be stressed, however, that these children had no clinical symptoms of hearing loss.

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mentioning

confidence: 99%

Possible Effects of Kanamycin and Incubation in Newborn Children With Low Birth Weight

et al. 1978

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“…The sensorineural hearing loss associated with haemolytic disease of the newborn can occur without simultaneous athetosis or other neurological damage (15). On the other hand, hearing loss associated with neonatal hyperbilirubinaemia in otherwise healthy, fullterm infants without iso-immunization has not, to our knowledge, been described previously with certainty (3,8,12,15,16,17,23).…”

Section: Sensorineural Hearing Defectsmentioning

confidence: 78%

“…In Sweden a similar figure has been reported by Barr & Klockhoff (2); among a series of children with athetosis they found that 70 % had neurogenic hearing damage. The development of sensorineural hearing loss has also been described in infants with haemolytic disease of the newborn due to A or B immunization (8,15), and in pLemature infants with hyperbilirubinaemia without iso-immunization (8,16). The sensorineural hearing loss associated with haemolytic disease of the newborn can occur without simultaneous athetosis or other neurological damage (15).…”

Section: Sensorineural Hearing Defectsmentioning

confidence: 99%

“…The development of sensorineural hearing loss has also been described in infants with haemolytic disease of the newborn due to A or B immunization (8,15), and in pLemature infants with hyperbilirubinaemia without iso-immunization (8,16). The sensorineural hearing loss associated with haemolytic disease of the newborn can occur without simultaneous athetosis or other neurological damage (15). On the other hand, hearing loss associated with neonatal hyperbilirubinaemia in otherwise healthy, fullterm infants without iso-immunization has not, to our knowledge, been described previously with certainty (3,8,12,15,16,17,23).…”

Section: Sensorineural Hearing Defectsmentioning

confidence: 99%

“…The hearing loss mainly affects the higher frequencies, with a maximum degree of impairment in the range of 2 000 to 4 000 c/s (8,16). As a rule the hearing loss is approximately equal on both sides (16), but unilateral deafness has also been described (15).…”

Section: Sensorineural Hearing Defectsmentioning

confidence: 99%

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A Follow‐up Study of Hyperbilirubinaemia in Healthy, Full‐term Infants Without Iso‐immunization

Bengtsson

Verneholt

1974

Acta Paediatrica

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Summary With the aim of shedding light on the indications for exchange transfusion in healthy, full term infants without iso‐immunization, a detailed follow‐up investigation was made of 226 children, of whom 111 had had neonatal hyperbilirubinaemia with maxima) bilirubin values of 20–51 mg/100 ml and the other 115 (controls) had had no visible jaundice neonatally. The children underwent physical and neurological examinations as well as audiometric and psychological tests. Among the 111 children with neonatal hyperbilirubinaemia 2 had coordination disturbances of the athetotic type and 4 had sensorineural hearing impairment, while none of the 115 control children had such disorders. The differences in the frequencies of the e conditions were not statistically significant, however. Neither did the frequencies of subnormal intelligence and psychological disturbances in the two groups differ significantly. Exchange transfusion is recommended in healthy, full‐term infants without iso‐immunization as'a measure to prevent the serum bilirubin level from exceeding 25 mg 100 ml.

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CNS Abnormalities After Neonatal Hemolytic Disease or Hyperbilirubinemia

Hyman¹

1969

Am J Dis Child

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Hearing Problems Subsequent to Neonatal Hemolytic Disease or Hyperbilirubinemia

Cited by 7 publications

References 4 publications

Possible Effects of Kanamycin and Incubation in Newborn Children With Low Birth Weight

Possible Effects of Kanamycin and Incubation in Newborn Children With Low Birth Weight

A Follow‐up Study of Hyperbilirubinaemia in Healthy, Full‐term Infants Without Iso‐immunization

CNS Abnormalities After Neonatal Hemolytic Disease or Hyperbilirubinemia

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