Hearing loss in autoimmune disorders: Prevalence and therapeutic options

Mancini, Patrizia; Atturo, Francesca; Mario, Alessia Di; Portanova, Ginevra; Ralli, Massimo; Virgilio, Armando De; Vincentiis, Marco de; Greco, Antonio

doi:10.1016/j.autrev.2018.01.014

Cited by 46 publications

(35 citation statements)

References 129 publications

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“…Other associated treatments include antioxidant compounds to avoid progression of SNHL [142], hearing aids to support the residual hearing function, or cochlear implants in case of severe and profound SNHL [143, 144]. …”

Section: Inner Ear Involvement In Autoimmune Diseasesmentioning

confidence: 99%

Audiovestibular Symptoms in Systemic Autoimmune Diseases

Ralli

D’Aguanno

Stadio

et al. 2018

Journal of Immunology Research

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Immune-mediated inner ear disease can be primary, when the autoimmune response is against the inner ear, or secondary. The latter is characterized by the involvement of the ear in the presence of systemic autoimmune conditions. Sensorineural hearing loss is the most common audiovestibular symptom associated with systemic autoimmune diseases, although conductive hearing impairment may also be present. Hearing loss may present in a sudden, slowly, rapidly progressive or fluctuating form, and is mostly bilateral and asymmetric. Hearing loss shows a good response to corticosteroid therapy that may lead to near-complete hearing restoration. Vestibular symptoms, tinnitus, and aural fullness can be found in patients with systemic autoimmune diseases; they often mimic primary inner ear disorders such as Menière's disease and mainly affect both ears simultaneously. Awareness of inner ear involvement in systemic autoimmune diseases is essential for the good response shown to appropriate treatment. However, it is often misdiagnosed due to variable clinical presentation, limited knowledge, sparse evidence, and lack of specific diagnostic tests. The aim of this review is to analyse available evidence, often only reported in the form of case reports due to the rarity of some of these conditions, of the different clinical presentations of audiological and vestibular symptoms in systemic autoimmune diseases.

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Section: Inner Ear Involvement In Autoimmune Diseasesmentioning

confidence: 99%

Audiovestibular Symptoms in Systemic Autoimmune Diseases

Ralli

D’Aguanno

Stadio

et al. 2018

Journal of Immunology Research

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“…Tinnitus has been described in many autoimmune conditions 39 ; in patients with MS it may follow SNHL may identify damages in specific areas of the cochlea sustained by a peripheral microglia aggression; however, so far their use has been always associated with ABR in clinical studies 45 because the evidence on the cochlea involvement in MS is still unclear.…”

Section: Hearing Loss and Tinnitusmentioning

confidence: 99%

Otolaryngologic Symptoms in Multiple Sclerosis: A Review

Ralli¹,

Stadio²,

Visconti³

et al. 2018

The International Tinnitus Journal

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Many symptoms of multiple sclerosis may affect the ear, nose and throat. The most common otolaryngologic symptoms of multiple sclerosis are speech disorders, followed by sleep disorders, vertigo and disequilibrium, dysphagia, smell alterations, and hearing loss. Less common symptoms include sialorrhea, facial palsy, taste alterations, trigeminal neuralgia and tinnitus. The origin of otolaryngologic symptoms in multiple sclerosis is mainly central, although increasing evidence also suggests a peripheral involvement.

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“…aging [24][25][26] , noise exposure 27 , the use of ototoxic drugs (28), autoimmune diseases [29,30] and other conditions [31][32][33][34][35] . According to WHO data, around 466 million people worldwide have disabling hearing loss, and 34 millions of these are children 36 .…”

Section: Benefits Of Hearing Dogsmentioning

confidence: 99%

Assistance Dogs for Persons with Hearing Impairment: A Review

Ralli¹,

Martellucci²,

Musacchio³

et al. 2019

The International Tinnitus Journal

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The use of dogs to help people with disabilities has been known for a long time. Assistance dogs carry out a variety of practical tasks for disabled people with appropriate and targeted training, including assisting deaf persons or people with profound hearing loss. The benefits of assistance dogs for persons with hearing impairment (hearing dogs) include a) improved ability to carry out daily tasks through the codified reporting of sounds proper of everyday life and/or of dangerous situations and b) psychosocial aspects such as companionship and sense of protection. The benefits derived from the use of assistance dogs for persons with hearing impairment are less studied compared to those of assistance dogs employed for other disabilities. Moreover, the role of hearing dogs may appear rather controversial considering technological advances in the field of surgical or prosthetic rehabilitation for people with hearing impairment. This article aims to review features and training of hearing dogs, the effects of their employment and legislative aspects for their owners.

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Hearing loss in autoimmune disorders: Prevalence and therapeutic options

Cited by 46 publications

References 129 publications

Audiovestibular Symptoms in Systemic Autoimmune Diseases

Audiovestibular Symptoms in Systemic Autoimmune Diseases

Otolaryngologic Symptoms in Multiple Sclerosis: A Review

Assistance Dogs for Persons with Hearing Impairment: A Review

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