Hearing loss: An unknown complication of pre‐eclampsia?

Terzi, Hasan; Kale, Ahmet; Hasdemir, Pınar Solmaz; Selçuk, Adın; Yavuz, Arzu; Genç, Selahattin

doi:10.1111/jog.12505

Cited by 5 publications

(2 citation statements)

References 23 publications

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“…Se ha descrito el efecto de enfermedades propias del embarazo sobre la audición. Terzi et al (15) realizaron un estudio caso-control prospectivo en el que compararon a pacientes embarazadas con diagnóstico de preeclampsia versus pacientes embarazadas normotensivas. Durante el tercer trimestre de embarazo todas fueron evaluadas con audiometría tonal pura y emisiones otoacústicas transcientes y concluyeron que la preeclampsia es un factor de riesgo para daño coclear e hipoacusia sensorio-neural.…”

Section: Cambios Auditivos Patológicos Durante El Embarazounclassified

Cambios auditivos durante el embarazo: revisión de la literatura

et al. 2016

Rev. Hosp. Clín. Univ. Chile (En línea)

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It is believed that the greater production of sex hormones during pregnancy cause changes that affect the hearing system, although their specific mechanisms are still under investigation. Physiological changes occur during pregnancy such as the non-pathologic drop of hearing thresholds for low frequencies and diminished hearing tolerance to intense sounds, both of which return to their basal range in the post-partum. Certain diseases, like sudden hearing loss, Ménière´s Disease and otosclerosis can appear for the first time or alter their course during pregnancy. A brief bibliographic revision is made regarding the physiological and pathological hearing changes that occur during pregnancy.

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Section: Cambios Auditivos Patológicos Durante El Embarazounclassified

Cambios auditivos durante el embarazo: revisión de la literatura

et al. 2016

Rev. Hosp. Clín. Univ. Chile (En línea)

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“…The findings indicate that PE has an adverse effect on the cochlear function by inducing the dysfunction of outer hair cells [ 8 ]. In addition, it was reported that patients with PE have a significantly higher hearing threshold than normal subjects [ 9 ]. Considering these studies’ findings, it can be suggested that PE has significant pathological outcomes in otology and nephrology, ophthalmology, cardiology, and neurology.…”

Section: Introductionmentioning

confidence: 99%

Cochlear pathology in preeclamptic rats: protective effects of vitamin D and magnesium sulfate

ALTINTAŞ,

HİDİŞOĞLU,

CERNOMORCENO

et al. 2023

Turkish Journal of Medical Sciences

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Background/aim This study investigated the possible degeneration in cochlear morphology induced by preeclampsia (PE) and the therapeutic/preventive effect of vitamin D (Vit D) and magnesium sulfate (MgSO 4 ) used separately and together on feto-maternal outcomes. Materials and methods We created PE in rats using a reduced uterine perfusion pressure (RUPP) animal model and recorded blood pressure (BP), embryonic survival (ES), and embryonic weight (EW) and evaluated cochlear morphology by electron microscopy. Results The PE group had elevated BP, a decreased number and weight of live pups, and significant degeneration in the cochlea compared to the sham group. In the PEV group, we observed significant beneficial effects of Vit D supplementation at 14.5 and 19.5 dpc in terms of BP (p < 0.05), EW (p < 0.001), and cochlear degeneration compared to the PE group. In the PEM group, BP (p < 0.05) and cochlear degeneration nearly reached the level found in the sham group. However, although the EW was statistically different in the PE group, it did not reach sham group levels. We also observed that BP returned to sham level (p < 0.01) and noticed significant increases in the EW (p < 0.0001) and ES (p = 0.017) in the PEMV group compared to the PE group. According to the scanning electron microscope results, combined administration of VitD and MgSO 4 is more effective than separate administration in improving cochlear degeneration induced by PE. Conclusion The administration of Vit D and MgSO 4 during pregnancy has beneficial effects on PE pathology and may play a significant role in preventing PE-related complications, including cochlear degeneration.

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