Abstract:Yellow fever vaccine (YFV) can have rare but severe adverse events, including YFV-associated neurologic disease (YEL-AND), YFV-associated viscerotropic disease (YEL-AVD), and anaphylaxis. Risks of YEL-AND and YEL-AVD increase with age. YEL-AND is characterized by encephalitis, meningitis, Guillain-Barré syndrome, or acute disseminated encephalomyelitis within 28 days after vaccination. Meningoencephalitis is the most common manifestation. Diagnosis can be aided by polymerase chain reaction testing of cerebrosp… Show more
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