“…We appreciate the opportunity to respond to this letter and thank Drs. Luiz Vancini, Santos Andrade, Knechtle, Theodoros Nikolaidis, and de Lira for their comments regarding our systematic review [1,2]. We reported that many articles (76.5%) did not describe any limitations concerning temporality when discussing the causality between psychological stress and seizure worsening in patients with epilepsy during the COVID-19 pandemic.…”