Health values of patients with systemic sclerosis

Abstract

Objective. To assess health values in subjects with systemic sclerosis (SSc) and determine variability explained by demographics, clinical factors, health status, and disease severity.

Reliability, validity, and minimally important differences of the SF-6D in systemic sclerosis

“…Although some studies have assessed health status in patients with SSc [21,30], the literature on preference measures in SSc is sparse [13].…”

“…Study 1 was a cross-sectional study assessing direct preference-based measures from patients with SSc [13]. The study recruited 110 participants 18 years and older with SSc, as defined by the American College of Rheumatology classification criteria [17], from the 2005 national Scleroderma Foundation annual meeting in Boston (n = 60) and from three local Scleroderma Foundation meetings in Cincinnati and Columbus, Ohio, and Los Angeles (n = 50); 107 participants completed the preference assessment and form the analytic group for study 1.…”

“…The SG score, also expressed on a scale from 0.0 to 1.0, was calculated by the following formula: 1 -the maximum acceptable probability of death. More details on the preference elicitation techniques are reported elsewhere [13].…”

“…To date, 1 study has assessed direct preference measures in patients with SSc have been published [13] but none have assessed indirect preference measures. We used data from two clinical studies to derive SF-6D scores in patients with SSc.…”

Valuation of quality of life in rheumatoid arthritis

“…The SG also demonstrated reliability (77,134). The results regarding construct validity of the TTO and SG were generally poor, with both instruments showing poor to moderate correlations with disease-or healthrelated outcome measures (78)(79)(80)132,(134)(135)(136)(137)(138)(139). Poor results were also found regarding their responsiveness (77,(138)(139)(140)(141)(142).…”