Health-related quality of life predictors in people with chronic wounds

Dantas, Janislei Soares; Silva, Clarice César Marinho; Nogueira, Wynne Pereira; Silva, Ana Cristina de Oliveira e; Araüjo, Edna Marília Nóbrega Fonseca de; Araújo, Patrí­cia da Silva; Freire, Maria Eliane Moreira

doi:10.1016/j.jtv.2022.07.017

Cited by 3 publications

(2 citation statements)

References 32 publications

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“…3 Furthermore, it is estimated that the incidence and prevalence of chronic wounds will continue to rise, consistent with the overall increase of chronic degenerative diseases and life expectancy. 4 Due to factors such as wound pain, limited mobility, and psychological disorders, the health-related quality of life of patients with chronic wounds is quite low. 5 Additionally, few studies have counted the indirect csosts associated with wounds (such as absenteeism, nutrition, and transportation), but the direct cost of chronic wounds is quite expensive.…”

Section: Introductionmentioning

confidence: 99%

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The clinical value of intelligent wound measurement devices in patients with chronic wounds: A scoping review

Wu,

2024

International Wound Journal

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Chronic wounds are common in clinical practice, with long treatment cycle and high treatment cost. Changes in wound area can well predict the effectiveness of treatment and the possibility of healing. Therefore, continuous wound monitoring and evaluation are particularly important. Traditional manual wound measurement tends to overestimate wound area. Recently, various intelligent wound measurement devices have been introduced into clinical practice. This review aims to summarise the reliability, validity, types and measurement principles of different intelligent wound measurement devices, so as to analyse the clinical value and application prospect. Articles numbering 2610 were retrieved from the database, and 14 articles met the inclusion criteria. The results showed that the intelligent wound measurement devices included in the study reported good reliability and validity. Contact devices can lead to wound bed damage, wound deformation, patient pain, and is not convenient for electronic wound recording; partial contact devices can complete continuous monitoring and recording of wounds, but are not sensitive to wound depth measurement. Non‐contact devices are more accurate in capturing wound images. In addition to wound measurement, they also have the function of wound assessment. In general, handheld and portable non‐contact devices have great clinical value and promotion prospects.

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Section: Introductionmentioning

confidence: 99%

“…The global prevalence of PUs is 12.8%, and the incidence of hospital‐acquired PUs is 8.4% 3 . Furthermore, it is estimated that the incidence and prevalence of chronic wounds will continue to rise, consistent with the overall increase of chronic degenerative diseases and life expectancy 4 …”

Section: Introductionmentioning

confidence: 99%

The clinical value of intelligent wound measurement devices in patients with chronic wounds: A scoping review

Wu,

2024

International Wound Journal

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A domain specific health-related quality of life of omani patients living with chronic wounds

Natarajan,

Joseph,

Al Alawi

et al. 2024

Journal of Tissue Viability

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Investigating the Wound Healing Activity of Silymarin Nanoemulsion Loaded in Chitosan Gel

Albarqi,

Ahmad,

Albekairi

et al. 2024

sci adv mater

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Wound healing is a complex biological process involving a series of coordinated cellular and molecular events to restore tissue integrity and functionality. Challenges in achieving optimal wound healing have prompted the search for innovative therapeutic strategies. In recent years, nanotechnology-based approaches have gained attention for their potential in promoting wound healing outcomes. Silymarin, a natural polyphenolic compound, possesses diverse therapeutic properties including anti-inflammatory, antioxidant, and wound healing effects. Loading these compounds in a chitosan-based nanoemulgel formulation enhances their stability, bioavailability, and targeted delivery to the wound site. In this study, we evaluated the efficacy of silymarin nanoemulsion-loaded chitosan gel (SLY-CS-NEG) through in vitro and in vivo experiments. The evaluation encompassed wound closure percentage, inflammation reduction, and tissue regeneration assessments. The selected formulation No (F6) of SLY-CS-NEG, boasted remarkable characteristics, with a mean droplet size of 49.94±0.21 nm, a negative surface charge of −29.9±0.61, and sustained drug release over the 24 h. Animal experiments unveiled that SLY-CS-NEG significantly promoted wound healing compared to the control group. The results of this study demonstrated that the nanomedicine-based approach utilizing chitosan and nanoemulsion technology presents an innovative solution to overcome the limitations of silymarin and advance wound healing therapies.

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Health-related quality of life predictors in people with chronic wounds

Cited by 3 publications

References 32 publications

The clinical value of intelligent wound measurement devices in patients with chronic wounds: A scoping review

The clinical value of intelligent wound measurement devices in patients with chronic wounds: A scoping review

A domain specific health-related quality of life of omani patients living with chronic wounds

Investigating the Wound Healing Activity of Silymarin Nanoemulsion Loaded in Chitosan Gel

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