Health-related quality of life of patients treated with primary chemoradiotherapy for oral cavity squamous cell carcinoma: a comparison with surgery

Crombie, A.; Farah, Camile S.; Batstone, Martin

doi:10.1016/j.bjoms.2013.09.014

Cited by 25 publications

(26 citation statements)

References 24 publications

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“…3,8 Head and neck cancer is among the diseases that can affect health-related QOL profoundly. 4,5,9,10,11,12 Most tools available for evaluation of QOL in head and neck cancer patients were developed originally in English, 13 and must be translated and validated for use in populations that speak other languages.…”

Section: Introductionmentioning

confidence: 99%

“…5,8 Each item is scored on a 0-100 scale. 3,14 Given the small number of QOL studies in patients with head and neck cancer, an expansion of knowledge about QOL assessment in patients undergoing cancer treatment is needed. 15 Therefore, the aim of this study was to evaluate the health-related QOL of patients with squamous cell carcinoma (SCC) according to tumor location.…”

Section: Introductionmentioning

confidence: 99%

“…2, 3,4,5,6,7 Generic questionnaires do not evaluate a specific disease; specific questionnaires are used to evaluate groups of patients with a certain type of disease in common. 3,8 Head and neck cancer is among the diseases that can affect health-related QOL profoundly.…”

Section: Introductionmentioning

confidence: 99%

“…The instruments used most commonly to assess health-related QOL in head and neck cancer are the 30-item Cancer-Quality of Life Questionnaire (QLQ-C30) and the 35-item Head and Neck Cancer-Quality of Life Questionnaire module (QLQ-HN35), developed by the European Organisation for Research and Treatment of Cancer (EORTC), and the University of Washington Quality of Life Questionnaire (UW-QOL). 2,3,4,6,8 The QLQ-C30 and QLQ-HN35 are instruments composed of questions that assess the patient's QOL in the last week with total score ranges of 0-100L. 3,14 The QLQ-C30, which is the EORTC's core QOL instrument, includes a single general health/QOL scale, five functional scales, eight physical symptom scales, and a single item related to financial difficulty (see Table 1 for scales).…”

Section: Introductionmentioning

confidence: 99%

“…2,3,4,6,8 The QLQ-C30 and QLQ-HN35 are instruments composed of questions that assess the patient's QOL in the last week with total score ranges of 0-100L. 3,14 The QLQ-C30, which is the EORTC's core QOL instrument, includes a single general health/QOL scale, five functional scales, eight physical symptom scales, and a single item related to financial difficulty (see Table 1 for scales). The QLQ-HN35 is the EORTC's head and neck cancer-specific module questionnaire (EORTC modules are each administered with the core QLQ-C30 assessment).…”

Section: Introductionmentioning

confidence: 99%

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Health-related quality of life of patients with squamous cell carcinoma: a comparison according to tumor location

Iriya

Romaniszen²,

Fernandes

et al. 2017

Braz. oral res.

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Health-related quality of life of patients with squamous cell carcinoma: a comparison according to tumor location Abstract: The aim of this study was to evaluate the health-related quality of life (QOL) of patients with squamous cell carcinoma (SCC) according to tumor location. The sample consisted of 27 patients with primary SCC in the oral cavity (n = 15), pharynx (n = 7), and larynx (n = 5) who were undergoing cancer treatment at the Cancer Hospital of Londrina, regardless of age, sex, clinical stage, and type of antineoplastic treatment. Health-related QOL was evaluated using the 30-item CancerQuality of Life Questionnaire (QLQ-C30), the 35-item Head and Neck Cancer-Quality of Life Questionnaire (QLQ-HN35), and the University of Washington Quality of Life Questionnaire (UW-QOL). These questionnaires were administered individually to each patient before ambulatory care. Sociodemographic data (age and sex) and clinical data (T stage, tumor location, and type of antineoplastic treatment) were collected from the patients' medical records. Scores were compared according to tumor location using the chi-squared test and one-way analysis of variance (p < 0.05). No score differed significantly according to tumor location. It can be concluded that the health-related QOL of patients with SCC was not influenced by tumor location.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Health-related quality of life of patients with squamous cell carcinoma: a comparison according to tumor location

Iriya

Romaniszen²,

Fernandes

et al. 2017

Braz. oral res.

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Quality of life following surgery for head and neck cancer: Evidence from ACRIN 6685

Hollenbeak,

Duan,

Subramaniam

et al. 2024

Head & Neck

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BackgroundThis study examined the trajectory of health‐related quality of life (HRQoL) for patients with clinical stage N0 HNSCC enrolled in ACRIN 6685 who underwent elective neck dissection(s).MethodsHRQoL of 230 patients in the ACRIN 6685 trial was measured prospectively up to 2 years following surgery using the University of Washington Quality of Life instrument.ResultsGeneral Health Within the Last 7 Days did not differ significantly from baseline at any follow‐up. General Health Relative to Before Cancer fell significantly by 5.8 points following surgery (p = 0.048), and then returned to 3.0 points above baseline at 1 year (p = 0.65). For Overall Quality of Life, HRQoL fell significantly by 4.3 points following surgery (p = 0.031) and then returned to levels not significantly different from baseline.ConclusionsPatients with stage N0 HNSCC experience significant declines in HRQoL immediately following surgery, including neck dissection, which recovers to near or better than baseline within 1–2 years.

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Quality of life after tongue cancer treatment and its influencing factors: A cross‐sectional study of Japanese patients

Sasahara

Kurawaki

Uchida

et al. 2023

Oral Science International

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AimThe post‐treatment quality of life (QOL) of patients with cancer has become an important issue owing to significant improvements in the outcomes of cancer treatment. The oral cavity has not only life‐sustaining functions but also important social functions, including talking. Thus, many reports have assessed the post‐treatment QOL of patients with oral cancer. However, the sample sizes in most studies were insufficient to control for potential confounding variables. Additionally, previous studies have indicated that racial/ethnic differences may be associated with health‐related QOL. Thus, this study aimed to clarify factors influencing post‐treatment QOL using multiple regression analysis in a large number of Japanese patients with tongue cancer.MethodsIn total, 106 patients with tongue cancer were recruited from the oral surgery departments of three university hospitals sharing a common treatment plan for tongue cancer. QOL was evaluated using the University of Washington Quality of Life Questionnaire, and depressive tendencies were assessed using the Self‐rating Depression Scale (SDS).ResultsNeck dissection was most widely associated with physical and socio‐emotional QOL. Reconstruction, radiotherapy, and higher T‐stage and SDS scores were the second most widely associated factors with QOL. Interestingly, a higher SDS score was negatively related only to socio‐emotional factors. Furthermore, only SDS scores were associated with the general QOL.ConclusionThis study suggested that the physical and socio‐emotional QOL was widely affected by neck dissection, reconstruction, radiotherapy, T‐stage, and SDS scores, whereas the general QOL was affected only by SDS scores. These findings should be considered when treating patients with oral cancer.

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Health-related quality of life of patients treated with primary chemoradiotherapy for oral cavity squamous cell carcinoma: a comparison with surgery

Cited by 25 publications

References 24 publications

Health-related quality of life of patients with squamous cell carcinoma: a comparison according to tumor location

Health-related quality of life of patients with squamous cell carcinoma: a comparison according to tumor location

Quality of life following surgery for head and neck cancer: Evidence from ACRIN 6685

Quality of life after tongue cancer treatment and its influencing factors: A cross‐sectional study of Japanese patients

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