Health-Related Quality of Life of COVID-19 Survivors Treated in Intensive Care Unit—Prospective Observational Study

Bugarin, Josipa Domazet; Šarić, Lenko; Delić, Nikola; Došenović, Svjetlana; Ilić, Darko; Saric, Ivana; Stipić, Sanda Stojanović; Duplančić, Božidar

doi:10.1177/08850666231158547

Cited by 2 publications

(4 citation statements)

References 24 publications

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“…However, in the second survey, the percentage of participants who experienced anxiety did not decrease significantly. Some studies have yielded similar results [30,[34][35][36]. Hoque et al [35] reported that symptoms of COVID-19 could affect the quality of life and emotional well-being of patients who have recovered from COVID-19.…”

Section: Discussionmentioning

confidence: 83%

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Quality of Life and Emotional Problems of COVID-19 Patients after Discharge: A One-Month Longitudinal Study

Wu,

Lin,

Chiu

et al. 2024

Healthcare

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Aim: The first coronavirus disease 2019 (COVID-19) outbreak in Taiwan occurred in May 2021 and many individuals were infected. All COVID-19 patients were quarantined in designated facilities until they fully recovered to prevent the spread of the disease. Prolonged quarantine could adversely affect these patients. In this study, we focused on investigating changes in the quality of life and mental health of individuals discharged from hospital after recovering from COVID-19. Methods: This study employed a longitudinal design and surveyed individuals discharged from a teaching hospital in northern Taiwan in 2021 within one week of their discharge and again after one month. An online questionnaire comprising the participants’ background, respiratory function (COPD Assessment Test), quality of life (WHOQoL-BREF), and emotional problems (DASS-21) was administered to the participants. Results: A total of 56 participants actively took part in both surveys. We observed that participants with abnormal respiratory function had a lower physical and psychological quality of life, especially those with severe symptoms requiring endotracheal intubation during the treatment period of COVID-19. Additionally, approximately 30% of participants experienced anxiety problems throughout this study period. Finally, patients with COVID-19 symptoms exhibited a lower quality of life and higher levels of severe emotional problems. Conclusions: According to our findings, it is necessary to monitor and provide appropriate interventions for individuals who have recovered from COVID-19, especially those who experienced severe symptoms that required endotracheal intubation during COVID-19 treatment. These interventions, such as symptom management and psychological support, can help improve their quality of life and reduce emotional problems. Therefore, after the participants are discharged, hospitals should regularly track the patients’ status and provide appropriate support or referrals to help these individuals. Otherwise, future research could include more participants and follow up with them for longer to investigate the longitudinal impact of COVID-19.

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Section: Discussionmentioning

confidence: 83%

“…However, some studies have reported contradictory results [34][35][36][37]. These studies conducted a cross-sectional survey on discharged patients who had severe COVID-19 symptoms and required hospitalization in the intensive care unit.…”

Section: Discussionmentioning

confidence: 99%

Quality of Life and Emotional Problems of COVID-19 Patients after Discharge: A One-Month Longitudinal Study

Wu,

Lin,

Chiu

et al. 2024

Healthcare

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“…There is a positive correlation between disease severity and the risk of development of PASC [19]. Persistence of symptoms of PASC subsequently impairs the QoL of COVID-19 survivors [5][6][7][8][9][10]. If PASC develops, the mental component of QoL is affected to the same or even to a greater extent than the physical component [10,11].…”

Section: Pathophysiological Backgroundmentioning

confidence: 99%

“…COVID-19 survivors also have a higher risk of developing severe cardiovascular, pulmonary, neurological, and psychiatric diseases, which may further impair their physical and mental health [4]. Persistence of symptoms affects the quality of life (QoL) of COVID-19 survivors, and the extent of the impact of COVID-19 sequelae on QoL correlates with the number and severity of persistent symptoms [5][6][7][8][9][10]. This affects both the physical and mental health of COVID-19 survivors.…”

Section: Introductionmentioning

confidence: 99%

Delayed Antibody Response in the Acute Phase of Infection Is Associated with a Lower Mental Component of Quality of Life in Survivors of Severe and Critical COVID-19

Dababseh,

Sabaka,

Duraníková

et al. 2024

JCM

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Background: The long-term sequelae of coronavirus disease 2019 (COVID-19) significantly affects quality of life (QoL) in disease survivors. Delayed development of the adaptive immune response is associated with more severe disease and a worse prognosis in COVID-19. The effects of delayed immune response on COVID-19 sequelae and QoL are unknown. Methods: We conducted a prospective study to assess the relationship between the delayed antibody response in the acute phase of infection in naïve unvaccinated patients suffering from severe or critical COVID-19 and their QoL 12 months after hospital discharge. The 12-item Short Form Survey (SF-12) questionnaire was used for assessment of QoL. The SF-12 evaluates both mental and physical components of QoL, incorporating a mental component score (MCS-12) and a physical component score (PCS-12). A delayed antibody response was defined as testing negative for anti-spike SARS-CoV-2 antibodies at the time of hospital admission. Results: The study included 274 patients (154 men and 120 women). Of the enrolled patients, 144 had a delayed immune response. These patients had a significantly lower MCS-12 (p = 0.002), but PCS-12 (p = 0.397) was not significantly different at the 12-month follow-up compared to patients with positive anti-spike SARS-CoV-2 antibodies. The MCS-12 at the time of follow-up was negatively associated with delayed antibody response irrespective of possible confounders (p = 0.006; B = 3.609; ηp2 = 0.035; 95% CI = 1.069–6.150). An MSC-12 below 50 points at the time of follow-up was positively associated with delayed antibody response (p = 0.001; B = 1.092; OR = 2.979; 95% CI = 1.554–5.711). Conclusions: This study confirmed that, in patients with severe and critical COVID-19, a negative result for anti-spike SARS-CoV-2 antibodies at the time of hospital admission is associated with a lower mental component of QoL in unvaccinated patients naïve to COVID-19 one year after hospital discharge.

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Health-Related Quality of Life of COVID-19 Survivors Treated in Intensive Care Unit—Prospective Observational Study

Cited by 2 publications

References 24 publications

Quality of Life and Emotional Problems of COVID-19 Patients after Discharge: A One-Month Longitudinal Study

Quality of Life and Emotional Problems of COVID-19 Patients after Discharge: A One-Month Longitudinal Study

Delayed Antibody Response in the Acute Phase of Infection Is Associated with a Lower Mental Component of Quality of Life in Survivors of Severe and Critical COVID-19

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