Health-related quality of life of stroke patientsʼ families during the patientsʼ hospitalization: a pilot study in Japan

Watanabe, Yuriko; Araki, Shiho; Kurihara, Masaki

doi:10.1097/00004356-200303000-00005

Cited by 2 publications

(1 citation statement)

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“…Stroke has considerable adverse physical and psychological impacts on patients over time. Stroke patients need help, understanding and care from their families [ 32 ]. Indeed, a growing body of research demonstrates the importance of family relationships for the recovery of functional capacity after stroke [ 33 , 34 ].…”

Section: Discussionmentioning

confidence: 99%

Development and validation of a patient-reported outcome measure for stroke patients

Luo

Yang

Zhang

2015

Health Qual Life Outcomes

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BackgroundFamily support and patient satisfaction with treatment are crucial for aiding in the recovery from stroke. However, current validated stroke-specific questionnaires may not adequately capture the impact of these two variables on patients undergoing clinical trials of new drugs. Therefore, the aim of this study was to develop and evaluate a new stroke patient-reported outcome measure (Stroke-PROM) instrument for capturing more comprehensive effects of stroke on patients participating in clinical trials of new drugs.MethodsA conceptual framework and a pool of items for the preliminary Stroke-PROM were generated by consulting the relevant literature and other questionnaires created in China and other countries, and interviewing 20 patients and 4 experts to ensure that all germane parameters were included. During the first item-selection phase, classical test theory and item response theory were applied to an initial scale completed by 133 patients with stroke. During the item-revaluation phase, classical test theory and item response theory were used again, this time with 475 patients with stroke and 104 healthy participants. During the scale assessment phase, confirmatory factor analysis was applied to the final scale of the Stroke-PROM using the same study population as in the second item-selection phase. Reliability, validity, responsiveness and feasibility of the final scale were tested.ResultsThe final scale of Stroke-PROM contained 46 items describing four domains (physiology, psychology, society and treatment). These four domains were subdivided into 10 subdomains. Cronbach’s α coefficients for the four domains ranged from 0.861 to 0.908. Confirmatory factor analysis supported the validity of the final scale, and the model fit index satisfied the criterion. Differences in the Stroke-PROM mean scores were significant between patients with stroke and healthy participants in nine subdomains (P < 0.001), indicating that the scale showed good responsiveness.ConclusionsThe Stroke-PROM is a patient-reported outcome multidimensional questionnaire developed especially for clinical trials of new drugs and is focused on issues of family support and patient satisfaction with treatment. Extensive data analyses supported the validity, reliability and responsiveness of the Stroke-PROM.Electronic supplementary materialThe online version of this article (doi:10.1186/s12955-015-0246-0) contains supplementary material, which is available to authorized users.

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Section: Discussionmentioning

confidence: 99%