Health‐related quality of life measures and psychiatric comorbidity in patients with migraine

Mula, Marco; Viana, Michele; Jauch, Regina; Schmitz, Bettina; Bettucci, D.; Cavanna, Andrea E.; Strigaro, Gionata; Tota, MG; Israel, Heike; Reuter, Uwe; Monaco, Francesco

doi:10.1111/j.1468-1331.2009.02636.x

Cited by 12 publications

(12 citation statements)

References 16 publications

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“…In the European trial, the Migraine Disability Assessment score, which indicates functional impairment by migraine [24], was significantly improved in the European trial but not in the US trial. In contrast, subdomains of the MSQ [25] showed significant differences in favor of topiramate [21] in the US trial.…”

Section: Topiramatecontrasting

confidence: 50%

Treatment of Chronic Migraine

Diener

Holle

Dodick

2010

Curr Pain Headache Rep

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Chronic migraine is defined in different ways. The most commonly used definition is headache on more than 15 days per month in patients with migraine. Chronic migraine is difficult to treat and requires a multidisciplinary approach. Only two pharmacological treatments have been shown to be effective in placebo-controlled randomized trials: topiramate and local injection of botulinum toxin. Both therapies are effective in patients with chronic migraine with and without medication overuse. Many other substances have been investigated in chronic daily headache. All trials were underpowered and, therefore, recommendations concerning possible efficacy are not possible.

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Section: Topiramatecontrasting

confidence: 50%

Treatment of Chronic Migraine

Diener

Holle

Dodick

2010

Curr Pain Headache Rep

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“…The impact of migraine on patients’ daily life has been assessed using measures of disability, activity limitation or HRQoL, often as secondary measures of treatment outcome [4–7, 9, 10]. Disability associated with migraine is strictly related to its severity: areas of functioning such as communication, mobility, self-care, participation in society, relationships with others [11] and with family members [12] are particularly affected.…”

Section: Introductionmentioning

confidence: 99%

A systematic review of the psychosocial difficulties relevant to patients with migraine

Raggi¹,

Giovannetti²,

Quintas³

et al. 2012

J Headache Pain

106

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Migraine is a common disease which causes significant burden to individuals, in terms of personal suffering and activity reduction, and to societies, in terms of disease cost. The purpose of this study is to identify the most relevant psychosocial difficulties related to migraine, the variables associated with them and the most relevant determinants of their evolution over time. MEDLINE and PsychINFO were searched for studies published in English between 2000 and 2010 that examined psychosocial difficulties in persons with migraine with and without aura, from clinical trials and observational studies. Information on the description of each difficulty, its determinants of onset and change over time and associated variables were extracted and categorized at a higher level. In total, 34 difficulties have been collected from 51 papers: the most frequent were reduced vitality and fatigue, emotional problems, pain, difficulties at work, general physical and mental health, social functioning and global disability. Evidence exists that pharmacological treatments have an impact toward improvement in patients’ difficulties, in particular emotional problems, physical and mental health, difficulties with employment and global disability. Migraine treatments and decreased headaches frequency are the major determinants of improvements in psychosocial difficulties, while no information is available for determinants of worsening; understanding the role of such factors is of primary public health relevance, given the high prevalence and the relevant personal and societal costs of migraine.Electronic supplementary materialThe online version of this article (doi:10.1007/s10194-012-0482-1) contains supplementary material, which is available to authorized users.

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“…The evaluation of the reduction of the impact of migraine after treatment interventions has been performed in several studies, which employed disability and HRQoL instruments as secondary measure of treatments' effectiveness, or in educational programs for migraine management . The results of these studies show that patients taking triptans report a decrease in disability in general and in missed workdays in working and productivity loss in particular.…”

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confidence: 99%

A 3‐Month Analysis of Disability, Quality of Life, and Disease Course in Patients With Migraine

et al. 2012

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In this study, migraine frequency and intensity were almost stable over 3 months, and an evident trend toward improvement was found in disability and in some health-related quality of life aspects, particularly in the social activity domain. Our results clearly indicate that continuity of care has a positive impact on patients' health status and functioning, also in stable patients already on anti-migraine therapy, and that the use of patient-oriented outcome measures is a viable way to capture such improvements.

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Health‐related quality of life measures and psychiatric comorbidity in patients with migraine

Cited by 12 publications

References 16 publications

Treatment of Chronic Migraine

Treatment of Chronic Migraine

A systematic review of the psychosocial difficulties relevant to patients with migraine

A 3‐Month Analysis of Disability, Quality of Life, and Disease Course in Patients With Migraine

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