Health-related quality of life measured with the EQ-5D-5L in critical care survivors: A cross-sectional study

Kang, Jiyeon; Yun, Seonyoung; Hong, Jiwon

doi:10.1016/j.iccn.2022.103252

Cited by 9 publications

(6 citation statements)

References 37 publications

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“…However, we found that it is difficult to evaluate the effect of QoL on patients' attitudes regarding the use of deferred consent when the vast majority of the patients were content with the procedure. Furthermore, in our study, the median EQ-value and median EQ-VAS score were higher after 6 months compared with previous studies evaluating functional status and QoL after ICU stay (20,21). Therefore, we cannot rule out that results will differ in patients with a severely impaired QoL.…”

Section: Discussioncontrasting

confidence: 86%

Perspectives of ICU Patients on Deferred Consent in the Context of Post-ICU Quality of Life: A Substudy of a Randomized Clinical Trial*

van der Wal,

Grim,

del Prado

et al. 2024

Critical Care Medicine

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Objectives: Deferred consent enables research to be conducted in the ICU when patients are unable to provide consent themselves, and there is insufficient time to obtain consent from surrogates before commencing (trial) treatment. The aim of this study was to evaluate how former ICU patients reflect on their participation in a study with deferred consent and examine whether their opinions are influenced by the quality of life (QoL) following hospital discharge. Design: Survey study by questionnaire. Setting: Eight ICUs in The Netherlands. Patients: Former ICU patients who participated in the ICONIC trial, a multicenter randomized clinical trial that evaluated oxygenation targets in mechanically ventilated ICU patients. Interventions: Participants enrolled in the ICONIC trial in one of the eight participating centers in The Netherlands received a questionnaire 6 months after randomization. The questionnaire included 12 close-ended questions on their opinion about the deferred consent procedure. QoL was measured using the EQ-5D-5L questionnaire. By calculating the EQ-5D index, patients were divided into four QoL quartiles, where Q1 reflects the lowest and Q4 is the highest. Measurements and Main Results: Of 362 participants who were contacted, 197 responded (54%). More than half of the respondents (59%) were unaware of their participation in the ICONIC study. In total 61% were content with the deferred consent procedure, 1% were not content, 25% neutral, 9% did not know, and 9% answered “other.” Those with a higher QoL were more likely to be content (p = 0.02). In all QoL groups, the legal representative was the most often preferred individual to provide consent. Conclusions: Former ICU patients who participated in the ICONIC study often did not remember their participation but were predominantly positive regarding the use of deferred consent. Those with a higher QoL were most likely to be content.

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Section: Discussioncontrasting

confidence: 86%

Perspectives of ICU Patients on Deferred Consent in the Context of Post-ICU Quality of Life: A Substudy of a Randomized Clinical Trial*

van der Wal,

Grim,

del Prado

et al. 2024

Critical Care Medicine

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“…Besides pain relief and function improvement, patients with KOA had a higher quality of life after m-PRP injections at 6 month (WMD = 2.58; 95%CI, −0.37 to 5.52, p = 0.09) follow-ups. The EQ-VAS questionnaire shows patients’ self-rated health state by using a visual analog scale [ 65 ]. The result presented that both m-PRP and m-HA injections could increase patients’ EQ-VAS scores, while the patients in the m-PRP group had higher scores than m-HA group.…”

Section: Discussionmentioning

confidence: 99%

Multiple Injections of Platelet-Rich Plasma Versus Hyaluronic Acid for Knee Osteoarthritis: A Systematic Review and Meta-Analysis of Current Evidence in Randomized Controlled Trials

Xing

Yan

et al. 2023

JPM

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In recent years, various clinical trials have focused on treating knee osteoarthritis (KOA) with multiple injections of platelet-rich plasma (PRP). However, compared with the multiple hyaluronic acid (m-HA) injections, the clinical efficacy of multiple PRP (m-PRP) injections for KOA still remains controversial among these studies. Therefore,we aimed to compare the clinical effectiveness of m-PRP injections with m-HA injections in the treatment of KOA in this systematic review. Relevant clinical trials were searched via bibliographic databases, including Medline, PubMed, Embase, Web of Science, and Cochrane Central Register of Controlled Trials, to compare the m-PRP and m-HA injections in the treatment of KOA. Finally, fourteen randomized controlled trials, including 1512 patients, showed the postoperative VAS, WOMAC, IKDC, or EQ-VAS scores and were enrolled in this systematic review. Compared with the group of intra-articular m-HA injections, the group of intra-articular m-PRP injections was lower in the VAS scores at 3-month (WMD = −0.25; 95%CI, −0.40 to −0.10, P = 0.0009) and 12-month (WMD = −0.64; 95%CI, −0.79 to −0.49, p < 0.00001) follow-ups. In addition, the group of intra-articular m-PRP injections was also lower in the WOMAC scores at 1-month (WMD = −1.23; 95%CI, −2.17 to −0.29, p = 0.01), 3-month (WMD = −5.34; 95%CI, −10.41 to −0.27, p = 0.04), 6-month (WMD = −11.02; 95%CI, −18.09 to −3.95, p = 0.002), and 12-month (WMD = −7.69; 95%CI, −12.86 to −2.52, p = 0.004) follow-ups. Furthermore, compared with the group of intra-articular m-HA injections, the group of intra-articular m-PRP injections was higher in the IKDC scores at 3-month (WMD = 7.45; 95%CI, 2.50 to 12.40, p = 0.003) and 6-month (WMD = 5.06; 95%CI, 1.94 to 8.18, p = 0.001) follow-ups. However, the long-term adverse side of m-PRP injections for KOA still needs more large-scale trials and long-term follow-ups.

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“…Die Anzahl und Komplexität der behandelten Patient*innen sind nicht zuletzt pandemiebedingt stetig gestiegen [1,2,3,4]. Kritische Erkrankungen und deren Behandlungen sind jedoch für die meisten Patient*innen und ihre Angehörigen mit einer Vielzahl von psychischen und physischen Belastungen und daraus resultierenden Beeinträchtigungen der Lebensqualität verbunden [5,6,7,8,9,10,11].…”

Section: Hintergrundunclassified

Psychosoziale Betreuung auf der Intensivstation

Denke,

Voigt,

Krampe

et al. 2023

Anästhesiol Intensivmed Notfallmed Schmerzther

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Health-related quality of life measured with the EQ-5D-5L in critical care survivors: A cross-sectional study

Cited by 9 publications

References 37 publications

Perspectives of ICU Patients on Deferred Consent in the Context of Post-ICU Quality of Life: A Substudy of a Randomized Clinical Trial*

Perspectives of ICU Patients on Deferred Consent in the Context of Post-ICU Quality of Life: A Substudy of a Randomized Clinical Trial*

Multiple Injections of Platelet-Rich Plasma Versus Hyaluronic Acid for Knee Osteoarthritis: A Systematic Review and Meta-Analysis of Current Evidence in Randomized Controlled Trials

Psychosoziale Betreuung auf der Intensivstation

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