Health-related quality of life in patients with non-communicable disease: study protocol of a cross-sectional survey

Wilder, Lisa Van; Clays, Els; Devleesschauwer, Brecht; Pype, Peter; Boeckxstaens, Pauline; Schrans, Diego; Smedt, Delphine De

doi:10.1136/bmjopen-2020-037131

Cited by 14 publications

(13 citation statements)

References 76 publications

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“… a Data were from a cross-sectional study (the QAPICHE study, an acronym for “quality of life in patients with chronic disease”) conducted in Flanders, Belgium ( 18 ). Values are percentage (number/total) unless otherwise indicated.…”

Section: Resultsmentioning

confidence: 99%

“…We used data from a cross-sectional study (the QAPICHE study, an acronym for “quality of life in patients with chronic disease”) conducted in Flanders, Belgium. Detailed information on the study aims and methodology can be found elsewhere ( 18 ). In brief, the QAPICHE study provides insight into the HRQOL of chronically ill patients by comparing patient groups and investigating determinants.…”

Section: Methodsmentioning

confidence: 99%

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Polypharmacy and Health-Related Quality of Life/Psychological Distress Among Patients With Chronic Disease

et al. 2022

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Introduction To date, no study has investigated the impact of polypharmacy (use of ≥5 medications concurrently) on health-related quality of life (HRQOL) and psychological distress in a combined sample of chronic disease patients and patients with multimorbidity, using diverse HRQOL measures. This study aimed to explore the association between polypharmacy and HRQOL/psychological distress by using data from a cross-sectional study in Flanders (Belgium). Methods We analyzed cross-sectional survey data on 544 chronically ill patients recruited from June 2019 through June 2021. HRQOL was measured with the EuroQol-5 Dimension-5 Level questionnaire (EQ-5D-5L) and the 12-Item Short Form Health Survey (SF-12); psychological distress was measured with the Hospital Anxiety and Depression Scale (HADS). Multiple linear regression models were built to assess the association between polypharmacy and HRQOL/psychological distress. Results Overall, compared with patients without polypharmacy, patients with polypharmacy reported worse EQ-5D-5L index values, EuroQol visual analogue scale (EQ-VAS) scores, SF-12 physical component scores (PCS), SF-12 mental component scores (MCS), and HADS anxiety and depression subscales. In the final regression model adjusting for age, sex, educational attainment, and multimorbidity, polypharmacy remained significantly associated with lower HRQOL in terms of the EQ-5D-5L index (β = −0.12; P = .008), EQ-VAS (β = −0.11; P = .01), and SF-12 PCS (β = −0.15; P = .002) but not with psychological distress (HADS) and SF-12 MCS. Conclusion This study found that polypharmacy was negatively associated with the physical domain of HRQOL, but not with the mental domain, among patients with chronic diseases. These results may be especially important for patients with multimorbidity, given their greater risk of polypharmacy.

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Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Polypharmacy and Health-Related Quality of Life/Psychological Distress Among Patients With Chronic Disease

et al. 2022

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“…Meeting the ambitious SDGs target 3.4 would have substantial effects on life expectancy globally [9] . However, neglected disability attributed to the four major NCDs may lead to unhealthy longevity [11,12] . Since 1990, there has been a marked shift towards a greater proportion of burden due to years lived with disability (YLDs) from NCDs [13] .…”

Section: Introductionmentioning

confidence: 99%

Potential gains in health-adjusted life expectancy by reducing burden of non-communicable diseases: a population-based study

Zhang

Chen

et al. 2022

Preprint

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BackgroundThe United Nations Sustainable Development Goals (SDGs) target 3.4 aims to reduce premature mortality attributable to non-communicable diseases (NCDs) by one-third of their 2015 levels by 2030. Although meeting this target leads to longevity, survivors may suffer from long-term disability caused by NCDs. This paper quantifies the potential gains in health-adjusted life expectancy for people aged 30-70 years (HALE[30-70)) by examining the reductions in disability in addition to premature mortality. Additionally, we also assessed the feasibility of meeting the SDGs target 3.4.MethodsWe extracted data from the Global Burden of Disease Study 2019 for all NCDs and four major NCDs (cancers, cardiovascular diseases, chronic respiratory diseases, and diabetes mellitus) in 188 countries from 1990 to 2019. Bayesian age-period-cohort models were used to predict possible premature mortality in 2030. The life table was used to estimate the unconditional probability of death and HALE[30-70). Estimates of the potential gains in HALE[30-70) were based on three alternative future scenarios: a) eliminating all premature deaths and disability from a specific cause, b) meeting SDGs target 3.4, and survivors' disability is eliminated, and c) meeting SDGs target 3.4, but survivors remain disabled for the rest of their lives.ResultsIn 2030, the unconditional probability of premature mortality for four major NCDs in most countries remained at more than two-thirds of the 2015 baseline. In all scenarios, the high-income group has the greatest potential gains in HALE[30-70), above the global average of HALE[30-70). In scenario A, the potential gains in HALE[30-70) of reducing premature mortality for four major NCDs are significantly lower than those for all NCDs (range of difference for all income groups: 2.88 - 3.27 years). In scenarios B and C, the potential gains of HALE[30-70) in reducing premature mortality for all NCDs and the four major NCDs are similar (scenario B: 0.14 - 0.22, scenario C: 0.05 - 0.19). In scenarios A and B, countries from the high-income group have the greatest potential gains in HALE[30-70) from cancer intervention, whilst countries from the other income groups result in a greater possible HALE[30-70) gains from cardiovascular diseases control. In scenario C, countries from each income group have the largest potential gains in HALE[30-70) from diabetes reduction and chronic respiratory diseases prevention.ConclusionsAchieving SDGs target 3.4 remains challenging for most countries. The elimination of disability among the population who benefit from the target could lead to a sizable improvement in HALE[30-70). Reducing premature death and disability at once and attaching equal importance to each to in line with the WHO goal of "leaving no one behind".

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“…Non-communicable diseases have also been documented as a global challenge leading to diminished quality of life (QoL) [2], [7], [8]. Once considered as diseases of developed nations and ISSN: 2252-8806  affluent societies, statistics show that the non-communicable diseases are now posing a disproportionately large burden on low-and middle-income countries [9].…”

Section: Introductionmentioning

confidence: 99%

Assessment of health-related quality of life among patients with non-communicable diseases

Joshi

Jain

Joshi

et al. 2021

IJPHS

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Non-communicable diseases (NCDs) are a global challenge towards diminishing quality of life. Health related quality of life (HRQoL) is a widely accepted measure of burden of disease for individuals with chronic conditions. Due to paucity of data in Western Rajasthan, India, this study was planned to assess the HRQoL due to NCDs in Jodhpur, India. A descriptive cross-sectional study was planned in government NCD center of Jodhpur. Convenience sampling was used to select 398 respondents and socio demographic data was collected. Short Form–36 (SF-36) questionnaire was used to measure perceived effects due to NCDs across eight domains of analyzed using descriptive and inferential statistics. High combined mean scores were obtained in domains of Social Functioning (77.87) and Mental Health (75.36%) and lowest scores for General Health (54.70%), Bodily Pain (60.06%) and Role Emotional (60.33%). Males recorded higher mean scores than females across all domains with high statistical significance for Bodily Pain, Vitality, Role Physical and Mental Health. Findings suggested worst and least affected domains of regular life functions due to NCDs. Greater focus on emotional distress, active inclusion of females in national health programmes and integration of NCD control program with Mental Health Program would aid to improve overall HRQoL in affected individuals.

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Health-related quality of life in patients with non-communicable disease: study protocol of a cross-sectional survey

Cited by 14 publications

References 76 publications

Polypharmacy and Health-Related Quality of Life/Psychological Distress Among Patients With Chronic Disease

Polypharmacy and Health-Related Quality of Life/Psychological Distress Among Patients With Chronic Disease

Potential gains in health-adjusted life expectancy by reducing burden of non-communicable diseases: a population-based study

Assessment of health-related quality of life among patients with non-communicable diseases

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