“…Also, studying the factors related to HRQL at 6 months, the same authors observed that depression, assessed by the 28-item General Health Questionnaire, a previous history of Coronary Heart Disease (CHD), or the associated comorbidity had a negative effect on quality of life, with a worse clinical course in these patients when compared with those without these conditions. This results are in agreement with Ormel et al (Ormel et al, 2007) and Höfer et al (Höfer et al, 2005) who found that depression and anxiety are the most significant factors influencing HRQL in patients with heart disease, and with McBurney et al (McBurney et al, 2002), who observed that the presence of other illnesses had a negative effect on the PCS-12 seven months after an AMI, and that having more comorbidity tends to lower HRQL in all dimensions.…”