Health-related quality of life in the Dialysis Outcomes and Practice Patterns Study (DOPPS)

Mapes, Donna; Bragg‐Gresham, Jennifer L.; Bommer, Jürgen; Fukuhara, Shunichi; McKevitt, Patricia M.; Wíkström, Björn; Lopes, Antônio Alberto

doi:10.1016/s0272-6386(04)01106-0

Cited by 134 publications

(72 citation statements)

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“…The Kidney Disease Quality of Life Questionnaire-Short Form TM (KDQOL-SF TM ) questionnaire, which includes the MOS-SF-36 instrument and several multi-item scales targeted at QoL concerns with special relevance for patients with CKD, has become the most widely used disease-specific questionnaire for patients with CKD [26]. This tool has initially been developed for dialysis patients and was used in the Dialysis Outcomes and Practice Patterns Study (DOPPS) [27], but also has been used in renal transplant recipients. We have recently provided evidence that most of the sub-scales of the KDQOL-SF TM are reliable both in dialyzed and kidneytransplanted populations [28].…”

Section: Quality Of Life Assessment In Kidney-transplanted Patientsmentioning

confidence: 99%

Sleep disorders and quality of life in renal transplant recipients

2009

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Kidney transplantation provides the best outcome for patients with end-stage renal failure both in terms of morbidity and mortality and health-related quality of life (QoL). Health-related QoL has become recognized as an important outcome measure in patients with different chronic medical conditions, including chronic kidney disease (CKD). There are several factors in kidney-transplanted patients which have a negative impact on QoL in these patients. Sleep disorders, such as insomnia, sleep apnea syndrome (SAS), and restless legs syndrome (RLS), are common in kidney-transplanted patients and clearly belong to this group of factors, although there is only limited published data available about the association between sleep problems and QoL in this patient population. The prevalence of both insomnia and RLS is reduced in kidney-transplanted patients compared to dialysis patients, and it is similar to the prevalence observed in the general population. The prevalence of sleep apnea, however, is very high, around 30%. The association between the presence of these sleep disorders and impaired QoL has been relatively well documented in dialysis patients, but there is only scarce published information about this association in the kidney transplant population. In this paper, we will summarize data from the literature describing the impact of sleep problems, which are potentially treatable, on QoL in kidney-transplanted patients. We suggest that the appropriate diagnosis and management of sleep disorders may improve QoL in kidney-transplanted patients.

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Section: Quality Of Life Assessment In Kidney-transplanted Patientsmentioning

confidence: 99%

Sleep disorders and quality of life in renal transplant recipients

2009

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“…In addition, the abrupt cessation of smoking 14 days prior to admission to our hospital had caused mental irritability. Because chronic hemodialysis patients are subject to various stresses caused by their health status, financial status, employment status, and/or family responsibilities (6), it is difficult to quantify the degree of mental stress suffered by a hemodialysis patient. However, our patient did not complain of any particular emotional stress other than that caused by the cessation of smoking just 14 days prior to the onset of Takotsubo cardiomyopathy.…”

Section: Discussionmentioning

confidence: 99%

“…Although the exact mechanism of the left ventricular dysfunction has not been clarified, catecholamine cardiotoxicity induced by physical and/or emotional stress is a suspected trigger of this syndrome (5). Most hemodialysis patients complain of physical and mental stresses (6,7). However, there have been few reports of Takotsubo cardiomyopathy associated with hemodialysis.…”

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confidence: 99%

‘Takotsubo’ Cardiomyopathy in a Maintenance Hemodialysis Patient

et al. 2006

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An 84-year-old woman undergoing maintenance hemodialysis presented with chest discomfort lasting several days and electrocardiographic abnormalities. She had stopped smoking 2 weeks earlier and was experiencing irritability. Upon admission, electrocardiography showed ST-segment elevation in leads I, II, aVF, and V2-6 and an abnormal Q wave in leads II, III, and aVF. Ultrasound cardiography showed left ventricular anteroapical akinesia and basal hyperkinesia. The chest discomfort disappeared without specific therapy. During hospital days 1-5, the ST-segment elevation gradually improved. Giant negative T waves then developed. The left ventricular asynergy resolved by day 8. Radionuclide imaging with iodine-123-beta-methyl-p-iodophenyl pentadecanoic acid, but not with technetium-99 m-sestamibi, showed an apical defect. Elective coronary angiography showed no stenosis. 'Takotsubo' cardiomyopathy was diagnosed. After discharge, the patient continued regular dialysis without cardiac symptoms. We concluded that endogenously activated sympathetic nerve action in hemodialysis patients, especially those under emotional or physical stress, might be a causative factor for Takotsubo cardiomyopathy.

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“…Mental illness is associated with all-cause mortality, cardiovascular hospitalizations and death in people receiving hemodialysis [11]. In people treated by dialysis, mental illness has been repeatedly shown to be associated with higher mortality [12,13,14,15,16]. Depression or experiencing a major depressive episode contributes considerably towards hospitalization, acute kidney injury, incident end-stage renal disease (ESRD), declining kidney function and death in people with CKD not receiving dialysis [17,18,19,20,21].…”

Section: Introductionmentioning

confidence: 99%

Association of Co-Occurring Serious Mental Illness with Emergency Hospitalization in People with Chronic Kidney Disease

McPherson¹,

Barbosa‐Leiker²,

Daratha

et al. 2014

Am J Nephrol

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Background/Aims: Chronic kidney disease (CKD) and serious mental illness (SMI) are both associated with an increased risk for repeated hospitalization. The objective of this study was to determine if co-occurring SMI exacerbates the risk for subsequent hospitalization, particularly through the emergency department (ED), among people with CKD. Methods: People hospitalized in Washington State from April 2006 to December 2008 were separated into cohorts with diagnoses of CKD (n = 31,166), SMI (defined by schizophrenia and/or mood disorder; n = 20,167) or CKD with co-occurring SMI (n = 717), and a reference cohort without either diagnosis (n = 548,532). Main outcomes were rehospitalization for condition(s) other than mental illness: (1) through the ED; (2) any admission, and (3) admission resulting in death. Cox regression was used to analyze time to main outcomes controlling for prespecified covariates associated with rehospitalization. Results: The risk of rehospitalization via the ED was increased for people with CKD (hazard ratio, HR = 1.24, 95% confidence interval, CI = 1.21-1.28, p < 0.001) and co-occurring SMI (HR = 1.33, 95% CI = 1.29-1.38, p < 0.001) cohorts, but was significantly greater in the combined cohort (HR = 1.55, 95% CI = 1.40-1.73, p < 0.001). Similarly, the risk of any rehospitalization was increased for CKD (HR = 1.21, 95% CI = 1.17-1.25, p < 0.001) and co-occurring SMI (HR = 1.14, 95% CI = 1.11-1.17, p < 0.001) cohorts, while a significantly greater risk was observed for the combined cohort (HR = 1.36, 95% CI = 1.24-1.48, p < 0.001). The risk of rehospitalization resulting in death was not significantly increased in the combined cohort. Conclusion: In people with CKD, co-occurring SMI increased the risk of experiencing rehospitalization, particularly through the ED. Studies of strategies to address SMI in the CKD population are needed to mitigate the risk of repeat hospital admissions.

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Health-related quality of life in the Dialysis Outcomes and Practice Patterns Study (DOPPS)

Cited by 134 publications

References 0 publications

Sleep disorders and quality of life in renal transplant recipients

Sleep disorders and quality of life in renal transplant recipients

‘Takotsubo’ Cardiomyopathy in a Maintenance Hemodialysis Patient

Association of Co-Occurring Serious Mental Illness with Emergency Hospitalization in People with Chronic Kidney Disease

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