Health-related quality of life in inflammatory bowel disease

Drossman, Douglas A.; Patrick, Donald L.; Mitchell, C. Madeline; Zagami, E A; Appelbaum, Mark I.

doi:10.1007/bf01538073

Cited by 354 publications

(92 citation statements)

References 12 publications

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“…This questionnaire is a global measure of a subject’s perceptions, illness experience and functional status incorporating social, cultural, psychological and disease-related factors [16]. It is a generic questionnaire, based on 36 items with closed answers, evaluating 8 domains in order to estimate the health status and wellbeing.…”

Section: Methodsmentioning

confidence: 99%

Impact of Gluten Withdrawal on Health-Related Quality of Life in Celiac Subjects: An Observational Case-Control Study

Tontini¹,

Rondonotti²,

Saladino³

et al. 2010

Digestion

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Aims: To evaluate health-related quality of life (HRQoL) in celiac disease (CD) patients at the time of diagnosis and during a gluten-free diet (GFD). Patients and Methods: We enrolled 43 adult CD patients (18 with a typical and 15 with an atypical clinical presentation, and 10 with dermatitis herpetiformis, DH) and 86 age- and sex-matched healthy controls. We administered the Short Form 36 Health Survey (SF-36) questionnaire at diagnosis and after 1, 12 and 24 months of a GFD. Results: At the time of diagnosis CD patients showed significantly lower SF-36 scores than controls; this figure was observed in women but not in men. At baseline, both typical and atypical CD patients had lower SF-36 scores than controls, while DH patients showed a SF-36 profile comparable to that of controls. During a GFD the SF-36 scores improved continuously in CD patients and in the female subgroup, becoming similar to those of matched controls at 1-year follow-up. After gluten withdrawal typical and atypical CD patients improved their SF-36 scores and reached values comparable to those of controls. Conclusions: At diagnosis, CD patients perceived a poor HRQoL; this figure appears to be mostly associated with female gender. In all subgroups of CD patients with a low HRQoL at diagnosis, the GFD allowed progressive restoration of HRQoL perception.

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Section: Methodsmentioning

confidence: 99%

Impact of Gluten Withdrawal on Health-Related Quality of Life in Celiac Subjects: An Observational Case-Control Study

Tontini¹,

Rondonotti²,

Saladino³

et al. 2010

Digestion

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“…Several instruments have been validated. In particular, the IBDQ [21]sensitively detects differences in quality of life between groups and changes over time [22], while other instruments, particularly the Rating Form of IBD Patient Concerns (RFIPC) [23], provide rich qualitative data about the concerns of particular patient groups. The RFIPC has facilitated the determination of the normal worries or concerns of people with IBD in several different populations including a community sample of members of the Crohn’s and Colitis Foundation of America [24], gastro-intestinal out-patients [23], IBD patients in several different countries [25], IBD patients with a recent history of psychosocial counselling [26]and between genders [24, 26].…”

Section: Concerns and Stressors In Ibdmentioning

confidence: 99%

Facilitating Adjustment to Inflammatory Bowel Disease: A Model of Psychosocial Intervention in Non-Psychiatric Patients

Maunder

Esplen²

1999

Psychother Psychosom

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Background: There is no consensus about the most appropriate psychosocial interventions for people with inflammatory bowel disease (IBD) or the most appropriate criteria by which to select which patients might benefit from the available interventions. Nonetheless the perception that stress and other subjective factors contribute to suffering in IBD is persistent and professionals are often called upon to offer appropriate support. A model of normal psychosocial adjustment to IBD and the interventions which can improve difficulties with adjustment will facilitate rational therapeutic intervention and needed research in this area. Methods: A model of normal adjustment to IBD is developed from a synthesis of the empirical literature and clinical experience in a tertiary care medical/surgical IBD centre and is used to identify potential points of psychosocial intervention. Results: Normal adjustment to IBD can be understood as a process involving the interaction of a triad of adaptive challenges: illness uncertainty, loss and change, and suffering. Each of these challenges requires different criteria of psychosocial assessment and may lead to different interventions. Conclusions: Although the interventions available for improving adjustment to IBD have not been exhaustively investigated, the existing data support the value of further study. The model of psychosocial adjustment presented here provides a synthesis of the existing data and a starting point for further research.

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“…In the field of IBD, several instruments have been specifically designed to measure the HRQOL in patients with ulcerative colitis (UC) and Crohn’s disease (CD) [4, 5, 6, 7]. Mitchell et al [6]and Guyatt et al [7]designed and validated the Inflammatory Bowel Disease Questionnaire (IBDQ).…”

Section: Introductionmentioning

confidence: 99%

Validation of the Spanish Version of the Inflammatory Bowel Disease Questionnaire on Ulcerative Colitis and Crohn’s Disease

López-Vivancos

Casellas²,

Badı́a

et al. 1999

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The objective of this study is to validate the Spanish translation of the Inflammatory Bowel Disease Questionnaire (SIBDQ) on ulcerative colitis and Crohn’s disease by assessing its convergence validity, discriminatory power, reliability and sensitivity to change. For that purpose, 211 patients with inflammatory bowel disease (116 with ulcerative colitis and 95 with Crohn’s disease) completed the SIBDQ, the Psychological General Well-Being Index and the EuroQol. SIBDQ was repeated in those patients who remained in stable remission and in those with changes in clinical activity. Clinical activity was assessed by the Rachmilewitz and Harvey-Bradshaw indices. Correlations among scores of SIBDQ, EuroQol, Psychological General Well-Being Index and clinical indices of activity were all positive and comparable for both diseases (r = –0.50 to r = –0.70, p < 0.01). Analysis of variance showed that SIBDQ discriminates between different clinical degrees of activity. Cronbach’s α was 0.96 in ulcerative colitis and Crohn’s disease. SIBDQ was also highly reliable when it was repeated in clinically stable patients with ulcerative colitis (intraclass correlation coefficient = 0.82) and Crohn’s disease (intraclass correlation coefficient = 0.86). SIBDQ was sensitive to clinical changes in ulcerative colitis and in Crohn’s disease, whether patients entered remission (effect size –1.88 and –1.81, respectively) or relapsed (effect size 1.70 and 8.04, respectively). In conclusion, the Spanish version of the IBDQ has proven to be a valid, reliable and sensitive instrument to detect clinical changes in patients with ulcerative colitis and Crohn’s disease.

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Health-related quality of life in inflammatory bowel disease

Cited by 354 publications

References 12 publications

Impact of Gluten Withdrawal on Health-Related Quality of Life in Celiac Subjects: An Observational Case-Control Study

Impact of Gluten Withdrawal on Health-Related Quality of Life in Celiac Subjects: An Observational Case-Control Study

Facilitating Adjustment to Inflammatory Bowel Disease: A Model of Psychosocial Intervention in Non-Psychiatric Patients

Validation of the Spanish Version of the Inflammatory Bowel Disease Questionnaire on Ulcerative Colitis and Crohn’s Disease

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