Health-Related Quality of Life in Adolescents with Wheezing Attacks

The impact of preschool wheezing patterns on health-related quality of life at age 4 years

“…Similar to studies in adolescents [29], we also observed that wheezing has an impact on parental perceptions with regard to children's ''general health'' and ''bodily pain'' at preschool age. However, we did not observe any impact on ''self esteem'' or ''mental health'' [29], suggesting that perhaps the impact emerges after preschool age. The observation that a positive change in health was reported by parents for children with early and persistent wheezing compared to children who never wheezed is not unexpected.…”

“…Comparing the associations between preschool wheezing patterns and ''physical'' and ''psychosocial summary measures'' (tables 3 and 4), our findings support a previous finding in school-aged children: that a child's asthma particularly impairs the physical domains of HRQOL [2]. Similar to studies in adolescents [29], we also observed that wheezing has an impact on parental perceptions with regard to children's ''general health'' and ''bodily pain'' at preschool age. However, we did not observe any impact on ''self esteem'' or ''mental health'' [29], suggesting that perhaps the impact emerges after preschool age.…”

Asthma and Health Related Quality of Life in Childhood and Adolescence

“…Also, the presence of at least four wheezing attacks during the past year was associated with impaired adolescents' health related quality of life. Frequent wheezing attacks mostly affect adolescents' general health, bodily pain, self esteem and mental health (Mohangoo et al, 2007). Previous studies have also found that wheezing attacks more often have a physical impact than a psychosocial impact (Merikallio et al, 2005).…”

“…Most studies have focused on severity of symptoms to examine the impact of asthma symptoms on children's health related quality life; the results are conflicting (Everhart & Fiese, 2009). For example, disease severity is not consistently associated with children's health related quality of life in some studies (Erickson et al, 2002;Vila et al, 2003), whereas others report that children with moderate or severe asthma have a worse level of functioning in several domains of their health related quality of life compared to children with mild asthma (Annett et al, 2001;Merikallio et al, 2005;Mohangoo et al, 2007Mohangoo et al, , 2011Sawyer et al, 2000) suggesting there may be a 'dose-response' relationship between the frequency and intensity of children's asthma symptoms and their health related quality of life. Mohangoo et al (2007Mohangoo et al ( , 2011 evaluated health related quality of life in infants and adolescents with asthma-like symptoms, such as attacks of wheezing and shortness of breath (Mohangoo et al, 2007(Mohangoo et al, , 2011.…”

The Generation R study: a candidate gene study and genome-wide association study (GWAS) on health-related quality of life (HRQOL) of mothers and young children

“…At the general population level, the purpose of such studies is often to monitor the health status and wellbeing; for the purpose of public health policy, it is important to know the determinants of HRQOL in order to develop public health policies [5,6]. With regard to patients with a certain medical condition, clinicians assess the impact of the condition on HRQOL and the factors that determine quality of life in order to find ways for improving the patients' well-being [7][8][9][10]. In the case of intensive or new therapies, clinicians monitor the impact of therapy on HRQOL [11][12][13].…”