Health-Related Quality of Life in EORTC clinical trials — 30 years of progress from methodological developments to making a real impact on oncology practice

Quality of Life in Patients With Advanced Cancer: Differential Association With Performance Status and Systemic Inflammatory Response

“…However, over the past three decades, there has been an evolution toward the inclusion of quality-of-life parameters, and these are now recognized as a key component in clinical trial evaluations. 1,2 Indeed, the vast majority of clinical trials now report quality-of-life parameters as either primary or secondary end points, and trials that improve quality of life in patients with cancer are of increasing interest, particularly in patients with advanced cancer in whom the scope for improving survival has proved to be limited.…”

“…2 The EORTC QLQ-C30 assesses various patient-reported outcomes, including level of functioning, overall or global quality of life, and symptoms such as pain and depression.…”

Psychometric Validation of the Malaysian Chinese Version of the EORTC QLQ-C30 in Colorectal Cancer Patients

“…Numerous researchers indicate that patients with colorectal cancer disease experience impairment in their Health-related Quality of Life (HRQOL) (Gujral et al, 2008;Kilic et al, 2012;Abu-Helalah et al, 2014). The HRQOL research in patients with cancer underwent several developments over the last three decades with European Organization for Research and Treatment of Cancer (EORTC) playing a major role (Velikova et al, 2012). For example, the development and subsequent update of the EORTC cancer core Quality of Life questionnaire (QLQ-C30) contributes significantly in this regard (King, 1996).…”

Oral-health-related quality of life in patients with cancer: cultural adaptation and the psychometric testing of the Persian version of EORTC QLQ-OH17

“…The QoL Group and QoL Department of EORTC are international leaders in the development of patientreported outcome measures in oncology [13,14]. More recently, health care professionals from various disciplines at Oslo University in Norway have developed a supplementary module "EORCTC QLQ-OH17" to the EORCTC QLQ-C30 for oral and QoL assessment in cancer patients.…”