Health-related quality of life in patients with Achilles tendinopathy: Comparison to the general population of the United Kingdom

Lewis, Thomas; Yip, Grace; Robertson, Kenneth; Groom, William D.; Francis, Richard; Singh, Swaastick Kumar; Walker, Ruth; Abbasian, Ali; Latif, Ahmed

doi:10.1016/j.fas.2022.02.018

Cited by 6 publications

(5 citation statements)

References 16 publications

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“…Compared with the control population, QoL was reported to be worse, especially in the physical function, role-physical, bodily pain, and social functioning domains [ 19 , 25 , 30 , 35 , 36 ] and all EQ-5D domains except self-care. Lewis et al [ 35 ] found that patients with AT aged < 55 had a significantly reduced QoL compared with the general UK population (EQ-5D mean 0.79 AT v. 0.906 no AT).…”

Section: Resultsmentioning

confidence: 99%

“…Table 3 shows the mean score from the different QoL instruments (PROMs) used in the articles included in this review. In the studies included in this review that compare QoL among AT and no AT patients, AT patients generally reported poor QoL compared with no AT population [ 19 , 35 , 36 ]. The results for the healthy population was 1.0 using the EQ-5D [ 19 ], 0.856 ± 0.175 using the EQ-5D-5L [ 35 ] and 50 (mean 10) for the Physical Component Summary (PCS) and 50 (mean10) for the Mental Component Summary (MCS) of the SF-36 [ 36 ].…”

Section: Resultsmentioning

confidence: 99%

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Psychosocial and individual factors affecting Quality of Life (QoL) in patients suffering from Achilles tendinopathy: a systematic review

Vergés¹,

Martínez²,

Pascual³

et al. 2022

BMC Musculoskelet Disord

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Background Achilles tendinopathy (AT) is a joint condition that causes functional restrictions and pain. This condition negatively impacts patients' social connectedness and psychological well-being, reducing their quality of life (QoL). This review aims to summarise the current information on QoL in patients suffering from AT from different angles: compared to a healthy population, reported individual factors that influence it and the effects of some AT interventions on QoL. Methods A systematic review was conducted at PubMed, Cochrane, Google Scholar, and PsycINFO using tendinopathy and QoL-related keywords up to November 2021. Articles were included if they compared QoL to demographic factors such as age or gender, lifestyle factors (physical activity levels), comorbidity factors (diabetes, obesity), and/or a control group. Results Three hundred twenty-nine articles were reviewed; 23 met the inclusion criteria. SF-36, EQ-5D, and VISA-A were the most common instrument used. Patients with AT reported low QoL when compared to no AT population. When women were compared to men, women reported worse QoL. The patients who participated in different exercise programs (strengthening and stretching) showed improvements in QoL. Surgical AT intervention improved QoL, although results varied by age. Conclusion AT has a substantial impact on QoL. In AT patients, QoL is also influenced by specific individual factors, including gender and physical activity. Exercise, education, and surgical treatment improve QoL. We suggest more research on AT patients to better understand the aspects leading to poor QoL.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Psychosocial and individual factors affecting Quality of Life (QoL) in patients suffering from Achilles tendinopathy: a systematic review

Vergés¹,

Martínez²,

Pascual³

et al. 2022

BMC Musculoskelet Disord

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“…The paratenon is a densely vascularised and innervated elastic sheath that plays a vital role in developing painful midportion Achilles (para)tendinopathy ( 5 ). A dysfunction or pathology in the Achilles tendon area significantly decreases the patients’ health-related quality of life ( 6 , 7 ). Achilles tendinopathy also greatly impacts the patient’s socioeconomic status; over one-third (38%) report reduced work productivity ( 6 ).…”

Section: Introductionmentioning

confidence: 99%

Efficacy of shock wave therapy and ultrasound therapy in non-insertional Achilles tendinopathy: a randomised clinical trial

Stania,

Słomka,

Juras

et al. 2024

Front. Neurol.

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ObjectivePhysiotherapists and physicians continue to seek effective conservative treatments for Achilles tendinopathy. This study aimed to subjectively and objectively determine the therapeutic efficacy of radial shock wave therapy (RSWT) and ultrasound therapy in non-insertional Achilles tendinopathy.Materials and methodsThirty-nine patients with non-insertional Achilles tendinopathy were randomly assigned to three experimental groups, i.e., RSWT (group A), ultrasound therapy (group B), and placebo ultrasound (group C) groups. Before the intervention and at weeks 1 and 6 after the treatment, the patients were assessed using the Victorian Institute of Sport Assessment–Achilles (VISA-A) questionnaire and posturographic measurements of step initiation performed on the force platforms under two different conditions (non-perturbed transit and perturbed transit).ResultsSix weeks after therapy, all groups exhibited significantly increased VISA-A scores against the measurement at week 1 after therapy. The post-therapy percentage changes in VISA-A scores were significantly greater in group A compared to group B. The three-way ANOVA demonstrated that treatment type affected sway range in the frontal plane and mean velocity of the centre of foot pressure displacements in the sagittal and frontal planes during quiet standing before step initiation. The Bonferroni post-hoc test showed that the means of all those variables were significantly smaller for group A than for group B patients. The three-way ANOVA revealed an effect of the platform arrangement on transit time and double-support period. The Bonferroni post-hoc test revealed statistically longer transit time for the perturbed vs. non-perturbed trials; a reverse relationship was observed for the double-support period.ConclusionThe VISA-A showed that RSWT was significantly more effective than sonotherapy for alleviation of pain intensity as well as function and activity improvement in patients with non-insertional Achilles tendinopathy. Therefore, RSWT therapy can be used in clinical practice by physiotherapists to alleviate the symptoms of non-insertional Achilles tendinopathy. Objective data registered by force platforms during quiet standing before and after step initiation did not prove useful for monitoring the progress of treatment applied to patients with non-insertional Achilles tendinopathy between consecutive therapy interventions.Clinical trial registration:https://anzctr.org.au/Trial/Registration/TrialReview.aspx?ACTRN=12617000860369, identifier (ACTRN12617000860369).

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“…However, pathological tendon conditions such as tendinopathies are prevalent in the entire population with incidences of up to 10.52 per 1,000 persons per year [2]. Tendinopathies are Schmid et al Journal of Experimental Orthopaedics (2023) 10:81 characterized by persistent tendon pain and loss of function associated with mechanical loading [3] and could cause a reduced life quality [4], impairments of work and sportive performances [5], and underestimated high socio-economic costs [6]. The pathogenesis is understood as a continuum model with the end stage of degenerative tendinopathy [7], where symptoms may persist for decades [8].…”

Section: Introductionmentioning

confidence: 99%

Moderate evidence exists for four microRNAs as potential biomarkers for tendinopathies and degenerative tendon ruptures at the upper extremity in elderly patients: conclusion of a systematic review with best‐evidence synthesis

Schmid

Wegener

Hotfiel³

et al. 2023

J. exp. orthop.

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Purpose The aim of this systematic review was to investigate tendon-specific microRNAs (miRNAs) as biomarkers for the detection of tendinopathies or degenerative tendon ruptures. Also, their regulatory mechanisms within the tendon pathophysiology were summarized. Methods A systematic literature research was performed using the PRISMA guidelines. The search was conducted in the Pubmed database. The SIGN checklist was used to assess the study quality of the included original studies. To determine the evidence and direction of the miRNA expression rates, a best-evidence synthesis was carried out, whereby only studies with at least a borderline methodological quality were considered for validity purposes. Results Three thousand three hundred seventy studies were reviewed from which 22 fulfilled the inclusion criteria. Moderate evidence was found for miR-140-3p and miR-425-5p as potential biomarkers for tendinopathies as well as for miR-25-3p, miR-29a-3p, miR-140-3p, and miR-425-5p for the detection of degenerative tendon ruptures. This evidence applies to tendons at the upper extremity in elderly patients. All miRNAs were associated with inflammatory cytokines as interleukin-6 or interleukin-1ß and tumor necrosis factor alpha. Conclusions Moderate evidence exists for four miRNAs as potential biomarkers for tendinopathies and degenerative tendon ruptures at the upper extremity in elderly patients. The identified miRNAs are associated with inflammatory processes.

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Health-related quality of life in patients with Achilles tendinopathy: Comparison to the general population of the United Kingdom

Cited by 6 publications

References 16 publications

Psychosocial and individual factors affecting Quality of Life (QoL) in patients suffering from Achilles tendinopathy: a systematic review

Psychosocial and individual factors affecting Quality of Life (QoL) in patients suffering from Achilles tendinopathy: a systematic review

Efficacy of shock wave therapy and ultrasound therapy in non-insertional Achilles tendinopathy: a randomised clinical trial

Moderate evidence exists for four microRNAs as potential biomarkers for tendinopathies and degenerative tendon ruptures at the upper extremity in elderly patients: conclusion of a systematic review with best‐evidence synthesis

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