Health-related quality of life improves during one year of medical and surgical treatment in a European population-based inception cohort of patients with Inflammatory Bowel Disease — An ECCO-EpiCom study^☆

Abstract

Medical and surgical treatment improved HRQoL during the first year of disease. The majority of IBD patients in both Eastern and Western Europe reported a positive perception of disease-specific but not generic HRQoL. Biological therapy improved HRQoL in CD patients, while UC patients in need of surgery or biological therapy experienced lower perceptions of HRQoL than the rest.

Quality of life and patient preferences among Danish patients with ulcerative colitis – results from a survey study

“…The HRQoL as measured with SIBDQ compares to international studies [25][26][27] . Furthermore, a number of studies show that QoL is related to disease activity in patients with UC [28][29][30][31] .…”

Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE): Determining Therapeutic Goals for Treat-to-Target

“…As in CD, PROs are an important assessment outcome in UC and are likely to be required by regulatory agencies as primary or major secondary end points in registration drug trials in the future. Th e ultimate PRO in UC (as with CD above) is improvement in QoL ( 89 ). To achieve this, the primary PRO target for UC should be resolution of rectal bleeding and normalization of bowel habit; the patient's individual goals should also be addressed.…”

Effect of psychosocial stressors on patients with Crohn’s disease: threatening life experiences and family relations

“…Short Inflammatory Bowel Disease Questionnaire [27] This instrument, which measures disease-specific quality of life in IBD, has physical (systemic and bowel symptoms), social, and emotional dimensions. It consists of 10 items: each item refers to the last 2 weeks and is rated on a 7°s cale (1 = all the time, 7 = never).…”