Health-Related Quality of Life for Patients With Progressive Multiple Sclerosis: Influence of Rehabilitation

Barriers and Facilitators Related to Rehabilitation Stays in Multiple Sclerosis

“…2,3 Motor and cognitive impairment, fatigue, depression, pain, incontinence, sexual dysfunction, and the unpredictability of the disease reduce health-related quality of life [4][5][6][7][8][9][10][11] and participation in work and life. 2,12,13 Although it has been difficult to show the effect of multidisciplinary rehabilitation stays in clinical trials, 14,15 several studies have suggested a positive effect of multidisciplinary rehabilitation on disability [15][16][17][18][19][20][21] and aspects of health-related quality of life. 15,17,18,20,21 A review by Khan et al 15 concluded that there was strong evidence that inpatient or outpatient rehabilitation can increase activity and participation in society, despite a lack of reduction in actual impairment.…”

“…2,12,13 Although it has been difficult to show the effect of multidisciplinary rehabilitation stays in clinical trials, 14,15 several studies have suggested a positive effect of multidisciplinary rehabilitation on disability [15][16][17][18][19][20][21] and aspects of health-related quality of life. 15,17,18,20,21 A review by Khan et al 15 concluded that there was strong evidence that inpatient or outpatient rehabilitation can increase activity and participation in society, despite a lack of reduction in actual impairment. Multidisciplinary rehabilitation has been shown to have a positive effect on measures of functional independence including locomotion, sphincter control, and self-care.…”

“…Multidisciplinary rehabilitation has been shown to have a positive effect on measures of functional independence including locomotion, sphincter control, and self-care. 16 In studies of health-related quality of life, improvement has been shown in fatigue, 17,18 pain, 17 general health, 17 physical health, 17,20,21 social function, 17,21 social support, 17 cognitive ability, 17 and emotional well-being. 20,21 with a neurologist, patients may contact one of four dedicated MS nurses at the outpatient clinic.…”

Rehabilitation in Multiple Sclerosis: Outcome Selection in Clinical Trials

“…In looking at trials designed to measure the package of multidisciplinary rehabilitation that have been undertaken in the past decade, it is evident that earlier research focused almost entirely on physical disability (Table 1). [2][3][4][5][6][7][8][9][10][11][12][13][14] In recent years, however, there has been increasing recognition that disability is only one of the many aspects of health affected by rehabilitation, and there has consequently been a broadening of the domains measured to include other aspects, such as handicaps and quality of life. This extension of the outcomes measured is important, because it is known from clinical experience that MS has a widespread impact on an individual.…”

Physical Rehabilitation in Multiple Sclerosis: General Principles and High-Tech Approaches

“…На протяже-нии последних двух десятилетий в исследованиях проде-монстрировали не только уменьшение степени выражен-ности некоторых нарушений (парезов, ходьбы, баланса), но и улучшение качества жизни пациентов при использо-вании различных методов и технологий, как, например, физические упражнения [40][41][42] и роботизированный локомоторный тренинг [43].…”