Health-related quality of life as a predictor of mortality and hospitalization: The Dialysis Outcomes and Practice Patterns Study (DOPPS)

Mapes, Donna; Lopes, Antônio Alberto; Satayathum, Sudtida; McCullough, Keith; Goodkin, David A.; Locatelli, Francesco; Fukuhara, Shunichi; Young, Eric W.; Kurokawa, Kiyoshi; Saitō, Akira; Bommer, Jürgen; Wolfe, Robert A.; Held, Philip J.; Port, Friedrich K.

doi:10.1046/j.1523-1755.2003.00072.x

Cited by 706 publications

(687 citation statements)

References 26 publications

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“…Studies that have investigated both diabetic and non-diabetic patients found similar results for the 11 subscales and the KDCS scores, with a trend towards higher scores in our study [25][26][27][28]. A Spanish study [47] compared quality of life of diabetic dialysis patients and unmatched non-diabetic patients using the SF-36 questionnaire and found significantly lower scores in seven out of eight subscales, but did not correct for the fact that the Spanish diabetic patients were significantly older than the non-diabetic patients (61.9± 13.5 vs 56.6±17 years).…”

Section: Diabetic Complications and Cardiovascular Diseasessupporting

confidence: 86%

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Diabetic patients treated with dialysis: complications and quality of life

et al. 2007

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Aims/hypothesis The aim of this study was to describe the prevalence of complications, health-related quality of life (HRQOL) and the influence of beliefs about control over health in diabetic dialysis patients. Methods Of 53 eligible diabetic patients on chronic dialysis during January 2004 in our clinic, 38 (76%) completed a kidney-specific (Kidney Disease Quality of Life) and a generic (SF-36) questionnaire and were characterised in terms of cardiovascular diseases and diabetic complications. Matched groups of non-diabetic dialysis patients (n= 40) and diabetic patients with a long duration of diabetes and normal kidney function (n=38) served as controls. Generic HRQOL was compared with matched data from a survey on the Danish general population (n=2248).

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Section: Diabetic Complications and Cardiovascular Diseasessupporting

confidence: 86%

“…The KDQOL-SF has been used in several studies of dialysis patients [26][27][28][29]. The English version has previously been translated into Danish and validated in Danish dialysis patients [30][31][32][33].…”

Section: Clinical Datamentioning

confidence: 99%

Diabetic patients treated with dialysis: complications and quality of life

et al. 2007

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“…4 Serum albumin concentration is a very powerful predictive variable of the risk of hospitalization and death. 4,8 However, it is influenced not only by nutrition but also by other parameters such as inflammation, comorbid conditions including depression, and dialysis practices such as the type of vascular access. The variations in serum albumin concentrations are predictive of death as well, which means that serial determinations of this parameter may be useful in day-today clinical practice, as suggested by the guidelines.…”

Section: Discussionmentioning

confidence: 99%

“…5,6 There is no doubt, as well, that quality of life or depression are other issues related to nutrition. 7,8 The results of the DOPPS related to nutrition are summarized in this article and discussed in relationship with the Clinical Practice Guidelines for Nutrition in Chronic Renal Failure. 1 …”

Section: T He Latest Version Of the Clinical Practice Guidelines For mentioning

confidence: 99%

“…7 In another report, US patients who had a 0.5 g/dL (5 g/L) lower serum albumin concentration had 28% greater odds of using a tunneled catheter (P Ͻ 0.001), with a similar nonsignificant trend in Europe. 6 Despite its limitations, mainly because it is strongly influenced not only by nutrition, but also by inflammation and other comorbidities, 8,11 albumin is a potent and robust indicator of both nutritional status and mortality risk.…”

Section: Serum Albuminmentioning

confidence: 99%

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Kidney Disease Outcomes Quality Initiative (K/DOQI) and the Dialysis Outcomes and Practice Patterns Study (DOPPS): Nutrition guidelines, indicators, and practices

Combe

McCullough

Asano³

et al. 2004

American Journal of Kidney Diseases

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• Background: Nutritional markers are important predictors of morbidity and mortality in dialysis patients. The Clinical Practice Guidelines for Nutrition in Chronic Renal Failure provides guidelines for assessing nutritional status that were evaluated using data from the Dialysis Outcomes and Practice Patterns Study (DOPPS). Methods: The level of various nutritional markers (serum albumin, modified subjective global assessment, serum creatinine, normalized protein catabolic rate [nPCR], and body mass index) were described for representative samples of patients and facilities from 7 countries (France, Germany, Italy, Spain, Japan, United Kingdom, and United States) participating in the DOPPS. Results: A strong inverse association was observed between mortality and serum albumin, with a mortality risk 1.38 times higher for patients with serum albumin concentration less than 3.5 g/dL (35 g/L). There were significant differences by country in the proportion of moderately and severely malnourished patients as determined by the modified subjective global assessment score. In the US sample, severely and moderately malnourished patients had a higher mortality risk compared with those not malnourished, 33% and 5% higher, respectively. An inverse relationship exists between serum creatinine concentration and mortality, with a mortality risk 60% to 70% higher in the lowest quartile group compared with the highest quartile group in Europe and the United States. Levels of nPCR varied significantly between European countries, and there was no association between mortality and nPCR in US data. After adjustment for demographic and comorbidity factors, the mortality risk decreased as body mass index increased in both US and European samples. Conclusion: DOPPS data highlight the importance of routine assessment of nutritional status, using multiple parameters, in clinical practice to improve patient care. Am J Kidney Dis 44(S2):S39-S46.

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