Health-related quality-of-life among patients with premature ovarian insufficiency: a systematic review and meta-analysis

Li, X. T.; Li, P. Y.; Liu, Y.; Yang, Huisheng; He, Liyun; Fang, Yigong; Liu, J.; Liu, B. Y.; Chaplin, John

doi:10.1007/s11136-019-02326-2

Cited by 26 publications

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“…The negative predictive values of AMH (98.61%%) and FSH (87.5%%) are also not similar, but the positive predictive value is the same (17.39%). AMH has a notably higher diagnostic accuracy than FSH [ 13 , 14 ].…”

Section: Discussionmentioning

confidence: 99%

“…The negative predictive values of AMH (98.61%%) and FSH (87.5%%) are also not similar, but the positive pre-dictive value is the same (17.39%). AMH has a notably higher diagnostic accuracy than FSH [13,14]. At present, several AMH detection methods are available clinically, including Gen II (Beckman Coulter), PICOAMH (Ansh Labs), AMH ELISA (Ansh Labs), ELECSYS (Roche), and Access (Beckman Coulter).…”

Section: Discussionmentioning

confidence: 99%

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Study of Serum Anti-Mullerian Hormone in the Diagnosis of Ovarian Reserve Function in Patients with Premature Ovarian Insufficiency

Yan¹,

Zhang²,

Yu³

et al. 2022

BioMed Research International

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Objective. To explore the diagnostic value of serum anti-Mullerian hormone (AMH) for patients with premature ovarian insufficiency (POI) and premature ovarian failure (POF). Methods. Totally, 125 women with menstrual disorder treated in the Obstetrics and Gynecology Department of Ningbo Women & Children Hospital between January 2020 and December 2021 were enrolled. Among them, based on the follicle-stimulating hormone (FSH) level, 54 patients ( 25 IU / L < FSH ≤ 40 IU / L ) were assigned to the POI group, and 71 patients ( FSH > 40 IU / L ) were assigned to the POF group. In addition, 72 individuals who went physical examination in the hospital and showed normal menstrual cycle were selected as the control (CON) group. Serum AMH in each group was quantified via enzyme-linked immunosorbent assay (ELISA) and Beckman Coulter Access active immunoassay analyzer, and the levels of serum neutral hormones [luteinizing hormone (LH), FSH, as well as estradiol (E2)] in each group were detected through the electrochemiluminescence method. The difference between AMH level acquired by the latest automatic method and that acquired by the traditional manual ELISA was compared, and the correlation of serum AMH with sex hormones was analyzed. In addition, receiver-operating characteristic (ROC) curves were drawn for determining the diagnostic value of serum AHM for POI ad POF. Results. Beckman Coulter Access quantified AMH more accurately and fastly (Beckman Coulter Access: 35 minutes; manual quantification: 3-4 hours) and was more sensitive than ELISA, with a requirement to less serum. The levels of serum AMH and E2 in the POF group were 0.04 ± 0.10 ng/mL and 35.16 ± 53.06 ng/mL, respectively, which were notably lower than those in the POI group (( 0.69 ± 1.46 ) ng/mL and ( 3.96 ± 2.82 ) ng/mL) and CON group (( 76.31 ± 97.84 ) ng/mL and ( 113.19 ± 114.84 ) ng/mL). The LH and FSH levels in the POF group were 37.86 ± 19.44 IU/L and 75.05 ± 35.31 IU/L, which were higher than those in POI group (( 22.66 ± 26.15 ) IU/L and ( 11.30 ± 17.05 ) IU/L) and the CON group (( 29.81 ± 4.45 ) IU/L and ( 6.78 ± 3.45 ) IU/L) ( P < 0.05 ). The POI group showed a notably lower serum AMH level and notably higher LH and FSH levels than the CON group ( P < 0.05 ), and the POI group was similar to the CON group in the E2 level ( P > 0.05 ). Serum AMH showed a positive correlation with E2 ( r = 0.291 , P < 0.05 ) and a negative association with both FSH ( r = − 0.476 , P < 0.05 ) and LH ( r = − 0.143 , P < 0.1 ). The optimal cut-off value of serum AMH in predicting POI was 0.83 ng/mL, and the corresponding sensitivity and specificity were 95.8% and 85.2%. The optimal cut-off of serum AMH in predicting POF was 0.075 ng/mL, and the corresponding sensitivity and specificity were 81.7% and 94.4%. The area under ROC curve (AUC) of serum AMH + FSH in the diagnosis of POF was close to 1. Conclusion. Beckman Coulter Access AMH test is the latest automatic electrochemiluminescence sandwich immunoassay, with higher sensitivity and reproducibility than traditional manual ELISA and with ability to produce repeatable results. With the decline of ovarian function, the serum AMH of POI patients decreases gradually, and the serum AMH of POF patients decreases obviously, so serum AMH level has great value in predicting POI and POF and can be used as a sensitive index for early diagnosis of the two. Serum AMH combined with FSH can lift the diagnostic efficiency of POF.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Study of Serum Anti-Mullerian Hormone in the Diagnosis of Ovarian Reserve Function in Patients with Premature Ovarian Insufficiency

Yan¹,

Zhang²,

Yu³

et al. 2022

BioMed Research International

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“…Infertilitet og mulige senkomplikasjoner gjør at den psykiske belastningen ved diagnosen kan vaere stor. I tillegg erfarer noen endret selvidentitet og opplevelse av for tidlig aldring (21). Flere studier viser også at prematur ovarialinsuffisiens kan gi redusert seksuell funksjon og tilfredsstillelse (22).…”

Section: Oppfølging Og Senkomplikasjonerunclassified

Prematur ovarialinsuffisiens

Vogt¹,

Russell²,

Øksnes³

et al. 2022

Tidsskriftet

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Medisinsk klinikkHaukeland universitetssjukehus og Universitetet i Bergen Forfa erbidrag: hovedansvaret for utarbeiding av manuskriptet. Elinor Chelsom Vogt er spesialist i indremedisin og i endokrinologi, er overlege og ph.d.-stipendiat. Forfa eren har fylt ut ICMJE-skjemaet og oppgir ingen interessekonflikter.Livio IVF-klinikken Oslo Forfa erbidrag: idé, utforming av manuskriptet og kritisk revisjon av innhold. Hannah Ni Bhriain Russell er spesialist i fødselshjelp og kvinnesykdommer. Forfa eren har fylt ut ICMJE-skjemaet og oppgir ingen interessekonflikter. Medisinsk klinikkHaukeland universitetssjukehus og Universitetet i Bergen Forfa erbidrag: idé, utforming av manuskriptet og kritisk revisjon av innhold. Marianne Øksnes er spesialist i indremedisin og i endokrinologi, overlege og førsteamanuensis. Forfa eren har fylt ut ICMJE-skjemaet og oppgir ingen interessekonflikter. KvinneklinikkenHaukeland universitetssjukehus Forfa erbidrag: idé, utforming av manuskriptet og kritisk revisjon av innhold. Agnethe Lund er ph.d., spesialist i fødselshjelp og kvinnesykdommer og klinikkoverlege. Forfa eren har fylt ut ICMJE-skjemaet og oppgir ingen interessekonflikter.Prematur ovarialinsuffisiens defineres som tap av ovariefunksjon før 40 års alder og er en kompleks tilstand med heterogen etiologi. Tidlig diagnose og igangse ing av hormonersta ende behandling er viktig for å lindre symptomer og forebygge senkomplikasjoner som følge av

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“…폐경의 연령이 낮을수록 스트레스 정도가 높 았던 반면에 [10] 신체적으로 활동적인 여성이 신체 증상 정도를 더 적게 경험하였으며 [12], 흡연 여성이 비흡연 여성보다 조기폐경 발 생이 많았다고 보고되었다 [13]. 조기폐경 후 나타나는 신체적, 정 신적 증상들과 건강 행태는 삶의 질을 위협하는 부정적인 요인으로 작용할 수 있다 [14,15].…”

Section: 조기폐경은 자연적으로 발생하는 일차성 폐경과 항암치료 방사unclassified

Comparison of quality of life and related factors according to premature menopause using the Korea National Health and Nutrition Examination Survey (2014-2017)

Cho¹,

Hwang²

2020

Korean J Women Health Nurs

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The purpose of this study was to compare the health-related quality of life of premature menopausal women with that of normal postmenopausal women and to identify factors related to quality of life in these two groups. Methods: A secondary analysis was conducted of a sample of 5,910 postmenopausal women drawn from women aged 19-79 years, using raw data from the Korea National Health and Nutrition Survey between 2014 and 2017. Quality of life was compared between premature menopausal women and normal postmenopausal women using the t-test and chi-square test, and factors related to quality of life were analyzed by multivariate logistic regression using SAS version 9.4. Results: There was no significant difference in quality of life between premature menopausal women and normal postmenopausal women. Subjective health status and symptoms of depression were identified as factors related to quality of life in women with premature menopause, while engaging in aerobic physical activity, subjective health status, stress, and symptoms of depression were found to be related to quality of life among normal postmenopausal women. Conclusion: It is necessary to support self-care measures for both premature and normal menopausal women to adapt to changes caused by menopause, and multidimensional strategies should be developed considering postmenopausal women's subjective health status and symptoms of depression to improve their quality of life.

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Health-related quality-of-life among patients with premature ovarian insufficiency: a systematic review and meta-analysis

Cited by 26 publications

References 92 publications

Study of Serum Anti-Mullerian Hormone in the Diagnosis of Ovarian Reserve Function in Patients with Premature Ovarian Insufficiency

Study of Serum Anti-Mullerian Hormone in the Diagnosis of Ovarian Reserve Function in Patients with Premature Ovarian Insufficiency

Prematur ovarialinsuffisiens

Comparison of quality of life and related factors according to premature menopause using the Korea National Health and Nutrition Examination Survey (2014-2017)

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