Health-related quality of life among cancer survivors in rural China

Su, Mingzhu; Hua, Xingxing; Wang, Jialin; Yao, Nengliang; Zhao, Di; Liu, Weidong; Zou, Yuewei; Anderson, Roger T.; Sun, Xiaojie

doi:10.1007/s11136-018-2038-6

Cited by 38 publications

(30 citation statements)

References 34 publications

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“…All EQ-5D studies and the AQoL study used the TTO method for valuation, whereas the SF-6D studies used the SG method. Only three studies collected data through a personal interview [32,46,55]. Most of the studies reported mean HSUVs (one reported median HSUVs [40]).…”

Section: Study Characteristicsmentioning

confidence: 99%

Systematic Review and Meta-Analysis of Community- and Choice-Based Health State Utility Values for Lung Cancer

2020

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Background Using appropriate health state utility values (HSUVs) is critical for economic evaluation of new lung cancer interventions, such as low-dose computed tomography screening and immunotherapy. Therefore, we provide a systematic review and meta-analysis of community-and choice-based HSUVs for lung cancer. Methods On 6 March 2017, we conducted a systematic search of the following databases: Embase, Ovid MEDLINE, Web of Science, Cochrane CENTRAL, Google Scholar, and the School of Health and Related Research Health Utility Database. The search was updated on 17 April 2019. Studies reporting mean or median lung cancer-specific HSUVs including a measure of variance were included and assessed for relevance and validity. Studies with high relevance (i.e. community-and choicebased) were further analysed. Mean HSUVs were pooled using random-effects models for all stages, stages I-II, and stages III-IV. For studies with a control group, we calculated the disutility due to lung cancer. A sensitivity analysis included only the methodologically most comparable studies (i.e. using the EQ-5D instrument and matching tariff). Subgroup analyses were conducted by time to death, histology, sex, age, treatment modality, treatment line, and progression status. Results We identified and analysed 27 studies of high relevance. The pooled HSUV was 0.68 (95% confidence interval [CI] 0.61-0.75) for all stages, 0.78 (95% CI 0.70-0.86) for stages I-II, and 0.69 (95% CI 0.65-0.73) for stages III-IV (p = 0.02 vs. stage I-II). Heterogeneity was present in each pooled analysis (p < 0.01; I 2 = 92-99%). Disutility due to lung cancer ranged from 0.11 (95% CI 0.05-0.17) to 0.27 (95% CI 0.18-0.36). In the sensitivity analysis with the methodologically most comparable studies, stage-specific HSUVs varied by country. Such studies were only identified for Canada, China, Spain, the UK, the USA, Denmark, Germany, and Thailand. In the subgroup analysis by time to death, HSUVs for metastatic non-small-cell lung cancer ranged from 0.83 (95% CI 0.82-0.85) at ≥ 360 days from death to 0.56 (95% CI 0.46-0.66) at < 30 days from death. Among patients with metastatic non-small-cell lung cancer, HSUVs were lower for those receiving third-or fourth-line treatment and for those with progressed disease. Results of subgroup analyses by histology, sex, age, and treatment modality were ambiguous. Conclusions The presented evidence supports the use of stage-and country-specific HSUVs. However, such HSUVs are unavailable for most countries. Therefore, our pooled HSUVs may provide the best available stage-specific HSUVs for most countries. For metastatic non-small-cell lung cancer, adjusting for the decreased HSUVs in the last year of life may be considered, as may further stratification of HSUVs by treatment line or progression status. If required, HSUVs for other health states may be identified using our comprehensive breakdown of study characteristics.

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Section: Study Characteristicsmentioning

confidence: 99%

Systematic Review and Meta-Analysis of Community- and Choice-Based Health State Utility Values for Lung Cancer

2020

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“…Asimismo, se encontró similar afectación en las dimensiones de dolor/malestar (33%) y ansiedad/depresión (28%) en otro estudio con migrantes en Inglaterra (30) . Sin embargo, en un estudio realizado en migrantes rurales mayores (edad promedio de 63 años) en China (31) , así como en estudios poblacionales en Perú (25) , Brasil (32) , Colombia (33) , y Chile (34) , si bien estas dos dimensiones suelen ser las más afectadas, la dimensión de dolor/malestar es más afectada que ansiedad/depresión.…”

Section: Discussionunclassified

Calidad de vida de migrantes venezolanos en dos ciudades del norte del Perú

Figueroa-Quiñones

Cjuno

Ipanaqué-Neyra

et al. 2019

Rev Peru Med Exp Salud Publica

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Citar como: Figueroa-Quiñones J, Cjuno J, Ipanaqué-Neyra J, Ipanaqué-Zapata M, Taype-Rondan A. Calidad de vida de migrantes venezolanos en dos ciudades del norte del Perú. Rev Peru Med Exp Salud Publica. 2019;36(3):383-91. doi: http://dx. RESUMENObjetivos. Describir la calidad de vida relacionada con la salud (CdV) de migrantes venezolanos que residen en las ciudades de Chimbote y Nuevo Chimbote en Perú y evaluar sus factores asociados. Materiales y métodos. Estudio transversal en 212 migrantes venezolanos reclutados por muestreo tipo bola de nieve. La CdV fue evaluada con el European Quality of Life-5 Dimensions en tres niveles (EQ-5D-3L). Los resultados fueron presentados descriptivamente. Para evaluar los factores asociados a CdV se emplearon regresiones lineales y regresiones ajustadas de Poisson. Resultados. El porcentaje de participantes afectados en cada dimensión de CdV fue: movilidad (1,4%), autocuidado (0,5%), actividades cotidianas (2,4%), dolor/malestar (18,4%) y ansiedad/depresión (68,9%). En cuanto a la Escala Visual Análoga (EVA) de CdV, la mediana del puntaje fue 85 (RIC: 70 a 90). Al evaluar los factores asociados, se encontró que ninguno de los factores evaluados se asoció al puntaje en la EVA o a presentar dolor/malestar. Sin embargo, la frecuencia de presentar ansiedad/depresión fue mayor en aquellos con grado de instrucción superior universitario en comparación con aquellos con estudios de secundaria (Razón de prevalencias ajustada 1,28; IC 95%: 1,03 a 1,60). Conclusiones. Los migrantes venezolanos que participaron del estudio reportaron problemas en su CdV, más de dos terceras partes reportaron ansiedad/depresión, y uno de cada seis presentó dolor/malestar. La frecuencia de presentar ansiedad/depresión fue mayor en aquellos con instrucción universitaria. ABSTRACT Objectives.To describe the health-related quality of life (HRQoL) of Venezuelan migrants residing in the cities of Chimbote and Nuevo Chimbote, in Peru, and assess its associated factors. Materials and Methods. Cross-sectional study of 212 Venezuelan migrants recruited by snowball sampling. The QoL was evaluated with the European Quality of Life-5 Dimensions at three levels (EQ-5D-3L). The results were presented descriptively. Linear regressions and Poisson adjusted regressions were used to evaluate the factors associated with QoL. Results. The percentage of participants affected in each QoL dimension was: mobility (1.4%), self-care (0.5%), usual activities (2.4%), pain/discomfort (18.4%), and anxiety/depression (68.9%). As for the QoL Visual Analog Scale (VAS), the median score was 85 (RIC: 70-90). In evaluating the associated factors, it was found that none of the factors was associated with the VAS score or pain/ discomfort. However, the frequency of anxiety/depression was higher in those with higher education (university) level compared to those with secondary education (RR 1.28; 95% CI: 1.03 to 1.60). Conclusions. Venezuelan migrants who participated in the study reported problems in their QoL; more than two-thirds reported anx...

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“…Because of these psychological stresses, those with breast cancer tend not to actively participate in many activities, which leads to the deterioration of cardiovascular health, muscle strength, and bone health, thus increasing the risk of osteoporosis and cardiovascular disease [7]. These diseases eventually cause activity restrictions for breast cancer survivors, including discomfort in daily life and absenteeism due to concurrent diseases [8]. In fact, 48.4% of breast cancer survivors in Korea are obese, which increases the risk of breast cancer recurrence and mortality to 35-40%, and may cause insulin resistance, metabolic syndrome, and type 2 diabetes [9].…”

Section: Introductionmentioning

confidence: 99%

Relationships between Exercise Modality and Activity Restriction, Quality of Life, and Hematopoietic Profile in Korean Breast Cancer Survivors

Kim

2020

IJERPH

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This study aimed to examine the relationships between activity restriction, quality of life (QoL), and hematopoietic profile in breast cancer survivors according to exercise modality. The subjects in this study were 187 female breast cancer survivors among a total of 32,631 participants in the Korea National Health and Nutrition Examination Survey, which was conducted from 2016 to 2018. The selected subjects participated in a questionnaire survey and blood analysis. A cross-analysis was conducted to determine the relationship between participation in various modality of exercise (e.g., aerobic exercise, resistance exercise, walking exercise). The phi coefficients or Cramer’s V value for activity restriction and QoL were calculated; an independent t-test was conducted to evaluate the differences between hematopoietic profiles based on the modality of exercise. Statistically significant correlations were seen between obesity and aerobic exercise and walking frequency, as well as between diabetes and aerobic exercise and activity restriction. With respect to QoL, there was a statistically significant correlation between participation in aerobic exercise and exercise ability, participation in aerobic exercise and anxiety/depression, participation in resistance exercise and subjective health status, participation in resistance exercise and exercise ability, and participation in weekly walking exercise and self-care ability. Regarding hemodynamic changes, red blood cells increased significantly in breast cancer survivors who participated in weekly resistance exercise compared to in those who did not. In conclusion, exercise participation had a positive effect on activity restriction, QoL, and hematopoietic profile in breast cancer survivors; in particular, some modalities of aerobic exercise were more effective.

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Health-related quality of life among cancer survivors in rural China

Cited by 38 publications

References 34 publications

Systematic Review and Meta-Analysis of Community- and Choice-Based Health State Utility Values for Lung Cancer

Systematic Review and Meta-Analysis of Community- and Choice-Based Health State Utility Values for Lung Cancer

Calidad de vida de migrantes venezolanos en dos ciudades del norte del Perú

Relationships between Exercise Modality and Activity Restriction, Quality of Life, and Hematopoietic Profile in Korean Breast Cancer Survivors

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